HUBUNGAN DERAJAT DIFERENSIASI HISTOPATOLOGIK DENGAN REKURENSI KANKER PAYUDARA DI RUMAH SAKIT UMUM ABDUL MOELOEK BANDAR LAMPUNG

RATNA AGUSTINA, 1218011123 (2016) HUBUNGAN DERAJAT DIFERENSIASI HISTOPATOLOGIK DENGAN REKURENSI KANKER PAYUDARA DI RUMAH SAKIT UMUM ABDUL MOELOEK BANDAR LAMPUNG. Fakultas Kedokteran, UNIVERSITAS LAMPUNG.

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ABSTRACT.pdf

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COVER DALAM.pdf

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COVER LUAR.pdf

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DAFTAR GAMBAR.pdf

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DAFTAR ISI.pdf

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DAFTAR LAMPIRAN.pdf

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DAFTAR TABEL.pdf

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HALAMAN PERSETUJUAN.pdf

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HALAMAN PENGESAHAN.pdf

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KATA PENGANTAR.pdf

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PERNYATAAN.pdf

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Abstrak

ABSTRAK Kanker payudara merupakan salah satu pembunuh utama wanita di dunia maupun di Indonesia. Terapi kanker payudara pun terus dilakukan seperti pembedahan, terapi hormonal, kemoterapi, maupun radiasi. Namun ternyata, banyak sekali kasus kanker payudara yang kembali kambuh atau rekuren setelah dilakukan pengobatan walaupun sudah dikatakan sembuh. Salah satu faktor risiko yang menyebabkan rekurensi kanker payudara yaitu derajat diferensiasi histopatologik. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara derajat diferensiasi histopatologik dengan rekurensi kanker payudara.Metode penelitian ini adalah observasional analitik retrospektif dengan pendekatan Case Control Design. Data didapat dari rekam medis penderita kanker payudara yang mengalami rekurensi maupun tidak mengalami rekurensi di Rumah Sakit Umum Abdul Moeloek Bandar Lampung pada tahun 2010-2015.Variabel yang dinilai meliputi derajat diferensiasi histopatologik dan rekurensi kanker payudara, selanjutnya dianalisis bivariat dengan Uji chi square. Dari hasil penelitian didapatkan 35 pasien yang mengalami rekurensi sebagai kasus dan 35 pasien tidak mengalami rekurensi sebagai kontrol. Dengan menggunakan analisis bivariat, derajat diferensiasi histopatologik antara kasus dan kontrol bermakna secara statistik (p=0,004) dan memiliki hubungan yang kuat sebagai faktor risiko rekurensi (OR=6,303). Kesimpulan dari penelitian ini adalah derajat diferensiasi histopatologik merupakan faktor risiko terjadinya rekurensi kanker payudara. Kata Kunci: derajat diferensiasi histopatologik, kanker payudara, rekurensi. ABSTRACT Breast cancer is one of the major killers of women in the world and in Indonesia. Treatments of breast cancer continues to be done such as surgery, hormonal therapy, chemotherapy, and radiation. However it turns out, there are many cases of breast cancer who relapsed or recurrent after treatment despite being said to be cured. One of the risk factors that lead to recurrence of breast cancer is the degree of histopathologic differentiation. The aim of this study was to determine the relationship between the degree of histopathologic differentiation with breast cancer recurrence. The Method of this study is a retrospective observational analytic with Case Control Design approach. Data obtained from the medical records of patients who experience a recurrence of breast cancer or did not experience recurrence in the General Hospital Abdul Moeloek Bandar Lampung in the years 2010-2015. In this research we use which degree of histopathologic differentiation and recurrence of breast cancer as variabels then analyzed bivariate with chi square test. The results of this study are 35 patients who experienced recurrence as cases and 35 patients who had not experienced recurrence as a control. By using bivariate analysis, the degree of histopathologic differentiation between cases and controls statistical significance (p = 0,004) and had a strong relationship as a risk factor for recurrence (OR = 6.303). The conclusion of this study is the degree of histopathologic differentiation a risk factor for breast cancer recurrence. Keywords: the degree of histopathologic differentiation ,breast cancer, recurrent.

Jenis Karya Akhir: Skripsi
Subyek: > RA Public aspects of medicine
> RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Program Studi: Fakultas Kedokteran > Prodi Pendidikan Dokter
Pengguna Deposit: 2883892 . Digilib
Date Deposited: 27 Jan 2016 07:19
Terakhir diubah: 27 Jan 2016 07:19
URI: http://digilib.unila.ac.id/id/eprint/20633

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