PERBEDAAN KADAR LIMFOSIT PRE DAN POST HEMODIALISIS PASIEN GAGAL GINJAL KRONIK DI RSUD Dr. H. ABDUL MOELOEK PROVINSI LAMPUNG TAHUN 2015

Rossadea Atziza, 1218011133 (2016) PERBEDAAN KADAR LIMFOSIT PRE DAN POST HEMODIALISIS PASIEN GAGAL GINJAL KRONIK DI RSUD Dr. H. ABDUL MOELOEK PROVINSI LAMPUNG TAHUN 2015. PROGRAM STUDI PENDIDIKAN DOKTER, UNIVERSITAS LAMPUNG.

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Abstrak

Gagal ginjal kronik adalah suatu kerusakan pada struktur atau fungsi ginjal yang berlangsung ≥ 3 bulan dengan atau tanpa disertai penurunan glomerular filtration rate (GFR). Terapi yang digunakan pada pasien gagal ginjal kronik salah satunya adalah hemodialisis. Pada pasien yang menjalani hemodialisis ditemukan adanya gangguan sistem imun yang dapat meningkatkan risiko infeksi sekunder. Gangguan ini ditandai dengan perubahan jumlah dan fungsi limfosit. Tujuan penelitian ini adalah untuk mengetahui perbedaan rerata kadar limfosit pre dan post hemodialisis pasien gagal ginjal kronik di RSUD Dr. H. Abdul Moeloek Provinsi Lampung Tahun 2015. Desain penelitian ini adalah deskriptif – analitik komparatif dengan pendekatan cross-sectional yang melibatkan 37 responden pasien gagal ginjal kronik yang menjalani hemodialisis. Hasil penelitian menunjukkan bahwa rerata kadar limfosit mengalami penurunan sebesar 298 ± 350,35413 setelah pasien menjalani hemodialisis. Berdasarkan hasil tersebut, disimpulkan bahwa terdapat perbedaan rerata kadar limfosit pre dan post hemodialisis yang bermakna dengan nilai p = 0,000 (p<0,05). Kata kunci: gagal ginjal kronik, hemodialisis, limfosit ABSTRAK BAHASA INGGRIS Chronic renal disease is a structural or functional kidney damage for ≥ 3 months, with or without decreased glomerular filtration rate (GFR). One of therapy used in patient with chronic renal disease is hemodialysis. Patient undergoing hemodialysis found to have immunity disorder that can increase the risk of secondary infection. This abnormality is characterized by changes in number and function of lymphocyte. The aim of this study is to find out the differences of pre and post hemodialysis lymphocyte levels in chronic renal failure patient at RSUD Dr. H. Abdul Moeloek Lampung Province 2015. Design of this study are descriptive – comparative analytic with crosssectional approach involving 37 patients of chronic renal disease undergoing hemodialysis. The result showed that the mean level of lymphocytes decreased by 298 ± 350,35413 after having a hemodialysis treatment. Based on these result, it was concluded that there is a significant differences of pre and post hemodialysis lymphocyte levels with p value = 0,000 (p<0,05). Keyword: chronic kidney disease, hemodialysis, lymphocytes

Tipe Karya Ilmiah: Skripsi
Subyek: Q Science (General)
Program Studi: Fakultas Kedokteran > Prodi Pendidikan Dokter
Depositing User: 1008319 . Digilib
Date Deposited: 28 Jan 2016 08:40
Last Modified: 28 Jan 2016 08:40
URI: http://digilib.unila.ac.id/id/eprint/20718

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