DAYA PROTEKSI EKSTRAK DAUN JAMBU BIJI MERAH (Psidium guajava Linn.) SEBAGAI REPELLENT TERHADAP NYAMUK Aedes aegypti

M Dwi Ario, 1118011070 (2015) DAYA PROTEKSI EKSTRAK DAUN JAMBU BIJI MERAH (Psidium guajava Linn.) SEBAGAI REPELLENT TERHADAP NYAMUK Aedes aegypti. Fakultas Kedokteran, Universitas Lampung.

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ABSTRAK.pdf

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COVER DALAM.pdf

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COVER LUAR.pdf

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DAFTAR ISI.pdf

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DAFTAR GAMBAR.pdf

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DAFTAR TABEL.pdf

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DAFTAR LAMPIRAN.pdf

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HALAMAN PENGESAHAN.pdf

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HALAMAN PERNYATAAN.pdf

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Abstrak (Berisi Bastraknya saja, Judul dan Nama Tidak Boleh di Masukan)

Abstrak Bahasa Indonesia ABSTRAK DAYA PROTEKSI EKSTRAK DAUN JAMBU BIJI MERAH SEBAGAI REPELLENT TERHADAP NYAMUK Aedes Aegypti Oleh M . DWI ARIO Demam Berdarah Dengue (DBD) merupakan penyakit infeksi yang berpotensi mematikan dan dapat ditularkan oleh nyamuk Aedes aegypti. Salah satu cara pencegahan penularan penyakit DBD adalah menghindari gigitan nyamuk Aedes aegypti dengan menggunakan repellent. Repellent yang banyak digunakan masyarakat sering terdiri dari bahan kimia yang bersifat korosif maka upaya pencarian senyawa alami yang dapat digunakan sebagai repellent lebih diutamakan. Daun Jambu Biji Merah memiliki kandungan zat aktif seperti alkaloid, flavonoid, saponin, tannin, dan minyak atsiri sebagai repellent di dalamnya. Tujuan penelitian ini adalah untuk mengetahui aktivitas ekstrak daun jambu biji merah sebagai repellent terhadap nyamuk Aedes aegypti. Penelitian ini merupakan penelitian eksperimental dengan metode rancangan acak lengkap mengikuti anjuran pedoman World Health Organization Pesticides Evaluation Scheme (WHOPES) yang dilakukan dari bulan Oktober hingga November 2014. Nyamuk Aedes aegypti dilakukan rearing di Laboratorium Zoologi Universitas Lampung. Pengujian repellent dilakukan dengan pengulangan 3 kali di hari yang berbeda. Lengan relawan dimasukkan ke dalam kurungan berisi 50 ekor nyamuk Aedes aegypti betina dewasa lalu diujikan sebagai repellent dengan dioleskan alkohol 70% sebagai kontrol negatif dan esktrak daun jambu biji merah konsentrasi 12,5%, 25% dan 50%. Daya proteksi masing-masing ekstrak daun jambu biji merah dianalisis menggunakan analisis One-way Anova dan estimasi dosis efektif (effective doses 50%; ED50 dan effective doses 99%; ED99) dianalisis menggunakan analisis Probit. Hasil penelitian menunjukkan ekstrak daun jambu biji merah konsentrasi 12,5%, 25% dan 50% memberikan daya proteksi sebesar 48%, 57,63% dan 82,96% serta nilai ED50 adalah 0,667% dan nilai ED99 adalah 282,747% terhadap nyamuk Aedes aegypti. Ekstrak daun jambu biji merah menunjukkan memiliki aktivitas repellent terhadap nyamuk Aedes aegypti. Kata kunci: Aedes aegypti, DBD, ekstrak daun jambu biji merah, repellent Abstract Bahasa Inggris ABSTRACT PROTECTION POWER OF Psidium guajava Linn. LEAF EXTRACTS AS REPELLENTS AGAINST Aedes aegypti By M . DWI ARIO Dengue Hemorrhagic Fever (DHF) is an infection disease, potentially causing death and can be transmitted by Aedes aegypti. One methode to prevent the transmission of DHF is to avoid mosquito bites by using repellent. Repellent, widely used in society, often formed by chemicals which are corrosive, then seeking natural compounds that can be used as repellent is preferred. Psidium guajava Linn. Leaf contains active substances such as alkaloid, flavonoid, saponin, tannin and essential oil as repellent in it. The aim of this study was to determine the activity of Psidium guajava Linn. leaf extract as repellent against Aedes aegypti. The study was an experimental design and follows the guidelines recommendation by the World Health Organization Pesticides Evaluation Scheme (WHOPES) from October to November 2014. Aedes aegypti was rearing in Zoology Laboratorium, University of Lampung. Repellent testing conducted in 3 times in different day. Volunter’s forearm inserted into the cage containing 50 adult female mosquitoes and apllied with diluent as repellent, alcohol 70% as negative control and Psidium guajava Linn. leaf extracts 12,5%, 25% and 50%. Protection power from mosquito bites calculated by One-way Anova test. Effective doses 50% and 99% (ED50 and ED99) value were calculated by Probit test. It showed Psidium guajava Linn. Leaf extract 12,5%, 25% and 50% give protection for 48%, 57,63% and 82,96% and then ED50 value were 0,667% and ED99 value were 282,747% for Aedes aegypti. Psidium guajava Linn. leaf extracts showed repellent activity against Aedes aegypti.Keyword: Aedes aegypti, DHF, Psidium guajava Linn. leaf extracts, repellen

Jenis Karya Akhir: Skripsi
Subyek:
Program Studi: Fakultas Kedokteran > Prodi Pendidikan Dokter
Pengguna Deposit: 4642637 . Digilib
Date Deposited: 29 Jan 2015 02:44
Terakhir diubah: 29 Jan 2015 02:44
URI: http://digilib.unila.ac.id/id/eprint/6604

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