PENGARUH PEMBERIAN EKSTRAK METANOL KULIT PISANG KEPOK LAMPUNG (Musa acuminata balbisiana colla)TERHADAP KADAR KOLESTEROL TOTAL PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR Sprague dawley YANG DIINDUKSI DIET TINGGI LEMAK

RR Astri Nur Azizah Utama, 1918011030 (2022) PENGARUH PEMBERIAN EKSTRAK METANOL KULIT PISANG KEPOK LAMPUNG (Musa acuminata balbisiana colla)TERHADAP KADAR KOLESTEROL TOTAL PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR Sprague dawley YANG DIINDUKSI DIET TINGGI LEMAK. Fakultas Kedokteran, Universitas Lampung.

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Abstrak

ABSTRACT THE EFFECT OF GIVING METHANOL EXTRACT OF LAMPUNG KEPOK BANANA PEEL (Musa acuminata balbisiana colla) ON TOTAL CHOLESTEROL OF MALE WHITE RATS (Rattus norvegicus) Sparague Dawley INDUCED BY HIGH DIET FAT By Rr Astri Nur Azizah Utama Background: Dyslipidemia is a lipid metabolism disorder which is a high risk factor for coronary heart disease. Musa acuminata balbisiana colla contains secondary metabolites which are thought to prevention on increasing in cholesterol. Methods: This research is an experimental study with a post-test only control group design carried out for 30 days using 20 experimental animals, Rattus norvegicus Sparague dawley. There were 4 treatment groups, they are KN was only given standard feed, K+ was given quail egg yolk induction, K- was given quail egg yolk induction and simvastatin 10 mg/day, KP was given quail egg yolk induction, respectively, and peel extract of Musa paradisiaca L. Then the rats were terminated using ketamine-xylazine and blood drawn through the heart to be checked for cholesterol. Results: The results of the normality test of saphiro-wilk and levene homogeneity obtained p>0.05. In the one-way anova test, cholesterol levels was 0.007 (p<0.05), which indicated that there were significant differences between groups. The results of the post hoc LSD test on K+ cholesterol were significantly different from KP (p<0.05). Conclusion: The administration of Musa acuminata balbisiana colla peel extract had an effect on preventing the increase in cholesterol levels in rats fed a high-fat diet. Keywords: Dyslipidemia, Musa acuminata balbisiana colla, Saba Bananan Cholesterol.

Jenis Karya Akhir: Skripsi
Subyek: 600 Teknologi (ilmu terapan) > 610 Ilmu kedokteran, ilmu pengobatan dan ilmu kesehatan
Program Studi: Fakultas Kedokteran > Prodi Pendidikan Dokter
Pengguna Deposit: 2208785316 . Digilib
Date Deposited: 24 Nov 2022 00:56
Terakhir diubah: 24 Nov 2022 00:56
URI: http://digilib.unila.ac.id/id/eprint/67109

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