BUNGA , ADGISTI (2024) DAYA PROTEKSI LOTION EKSTRAK ETANOL RUMPUT LAUT Sargassum polycystum SEBAGAI REPELLENT NYAMUK Aedes aegypti. FAKULTAS MATEMATIKA DAN ILMU PENGETAHUAN ALAM, UNIVERSITAS LAMPUNG .
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Abstrak (Berisi Bastraknya saja, Judul dan Nama Tidak Boleh di Masukan)
Repellent yang beredar di pasaran pada umumnya mengandung zat kimia sintetik yang cukup berbahaya seperti Diethyltoluamide (DEET). Salah satu jenis tanaman yang mengandung senyawa flavonoid, saponin dan tanin memiliki potensi sebagai repellent bagi serangga adalah rumput laut Sargassum polycystum. Penelitian ini bertujuan untuk mengetahui kandungan senyawa metabolit sekunder dengan metode Fourier-transform Infrared Spectroscopy (FTIR), mengetahui daya proteksi lotion sebagai repellent nyamuk Aedes aegypti, mengetahui stabilitas fisik (homogenitas) dan efek iritasi. Jenis penelitian ini adalah eksperimental dengan metode Rancangan Acak Lengkap (RAL) dengan 4 perlakuan dan 6 kali ulangan. Data berupa persentase daya proteksi dianalisis dengan one-way analysis of variance (ANOVA) menggunakan program SPSS dan dilanjutkan dengan uji Least Significant Difference (LSD). Hasil uji FTIR ekstrak etanol rumput laut Sargassum polycystum menghasilkan gugus fungsi O-H, N-H, C-H, C=O, C=C, C-O yang mengandung senyawa metabolit sekunder berupa senyawa flavonoid, tanin, saponin, alkaloid, steroid dan terpenoid. Hasil one-way ANOVA menunjukkan terdapat perbedaan daya proteksi yang signifikan antar konsentrasi dengan (p- value=0,00). Hasil uji lanjut (LSD) yaitu daya proteksi terbaik sebesar 83,88% pada konsentrasi 50%. Hasil uji stabilitas fisik menunjukkan lotion homogen pada konsentrasi 0%, 12,5%, 25% dan tidak homogen pada konsentrasi 50%. Hasil uji efek iritasi lotion ekstrak rumput laut Sargassum polycystum tidak memberikan efek iritasi pada kulit. Kesimpulan, ekstrak rumput laut Sargassum polycystum dalam sediaan lotion menunjukkan aktivitas sebagai repellent terhadap nyamuk Aedes aegypti. Kata Kunci : repellent, Sargassum polycystum, Aedes aegypti Repellents on the market generally contain quite dangerous synthetic chemicals such as Diethyltoluamide (DEET). One type of plant that contains flavonoids, saponins and tannins which have the potential to act as a repellent for insects is the seaweed Sargassum polycystum. This research aims to determine the content of secondary metabolite compounds using the Fourier-transform Infrared Spectroscopy (FTIR) method, determine the protective power of lotion as a repellent for the Aedes aegypti mosquito, determine physical stability (homogeneity) and irritation effects. This type of research is experimental with a Completely Randomized Design (CRD) method with 4 treatments and 6 replications. Data in the form of percentage of protective power were analyzed with one-way analysis of variance (ANOVA) using the SPSS program and continued with the Least Significant Difference (LSD) test. The FTIR test results of the ethanol extract of Sargassum polycystum seaweed produced the functional groups O-H, N- H, C-H, C=O, C=C, C-O which contain secondary metabolite compounds in the form of flavonoids, tannins, saponins, alkaloids, steroids and terpenoids. The results of one-way ANOVA show that there is a significant difference in protective power between concentrations (p-value=0.00). The results of further tests (LSD) were the best protective power of 83.88% at a concentration of 50%. The results of the physical stability test showed that the lotion was homogeneous at concentrations of 0%, 12.5%, 25% and not homogeneous at a concentration of 50%. The results of the test results for the irritating effect of the Sargassum polycystum seaweed extract lotion did not have an irritating effect on the skin. In conclusion, Sargassum polycystum seaweed extract in lotion preparation shows activity as a repellent against the Aedes aegypti mosquito. Keywords: repellent, Sargassum polycystum, Aedes aegypti
| Jenis Karya Akhir: | Skripsi |
|---|---|
| Subyek: | 500 ilmu pengetahuan alam dan matematika > 570 Biologi |
| Program Studi: | FAKULTAS MIPA > Prodi Biologi |
| Pengguna Deposit: | UPT . Siswanti |
| Date Deposited: | 08 Feb 2025 12:16 |
| Terakhir diubah: | 08 Feb 2025 12:16 |
| URI: | http://digilib.unila.ac.id/id/eprint/82696 |
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