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primary topic: http://digilib.unila.ac.id/id/eprint/115

http://digilib.unila.ac.id/id/eprint/115
type: Article
title: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210)
abstract: Pada penelitian ini telah dilakukan sintesis senyawa dibutiltimah(IV) di-3-nitrobenzoat, difeniltimah(IV) di-3-nitrobenzoat, dan trifeniltimah(IV) 3-nitrobenzoat dengan berat padatan putih masing-masing senyawa 87,10%, 84,06%, dan 83,64%, pada waktu refluks optimum empat jam. Hasil karakterisasi spektrofotometer IR menunjukkan adanya serapan C=O untuk senyawa tersebut berturut-turut adalah pada 1591,89 cm-1, 1705,36 cm-1, dan 1597,94 cm-1 yang menandakan terdapatnya gugus karbonil yang berasal dari asam 3-nitrobenzoat. Senyawa hasil sintesis berupa senyawa dibutiltimah(IV) di-3-nitrobenzoat, difeniltimah(IV) di-3-nitrobenzoat, dan trifeniltimah(IV) 3-nitrobenzoat juga dikarakterisasi dengan spektrofotometer UV-Vis untuk melihat pergeseran panjang gelombangnya. Data mikroanalisis menggunakan microelemental analyzer menunjukkan bahwa senyawa hasil sintesis telah murni dengan perbedaan hasil mikroanalisis dengan perhitungan secara teori berkisar 1-5%. Pengujian antikanker menunjukkan nilai IC50 masing-masing senyawa hasil yaitu 20,59; 9,29; dan 3,06, yang menunjukkan bahwa senyawa trifeniltimah(IV) 3-nitrobenzoat memiliki keakftifan terhadap antikanker yang lebih tinggi. (In this research, the synthesis of dibutyltin(IV) di-3-nitrobenzoate, diphenyltin(IV) di-3-nitrobenzoate, and triphenyltin(IV) 3-nitrobenzoate were performed which produced the white solid of 87.10%, 84.06%, and 83.64%, respectively in the optimum reflux time of 4 hours. The result of IR spectrophotometer characterization showed that there were absorption of C=O for those compounds at 1591.89 cm-1, 1705.36 cm-1, and 1597.94 cm-1 which indicated that there was carbonil group from 3-nitrobenzoate acid. The compounds synthesized as dibutyltin(IV) di-3-nitrobenzoate, diphenyltin(IV) di-3-nitrobenzoate, and triphenyltin(IV) 3-nitrobenzoate were also characterizated using UV-Vis spectrophotometer in order to see the shift of their wavelength. The microanalysis data using microelemental analyzer showed that …
date: 2013-12-23
status: published
author list: authors
type: EPrint
type: OtherEPrint
is part of: repository
has document: http://digilib.unila.ac.id/id/document/6779
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http://digilib.unila.ac.id/id/document/6789
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http://digilib.unila.ac.id/id/document/6790
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http://digilib.unila.ac.id/id/document/6791
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http://digilib.unila.ac.id/id/document/6798
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Fakultas MIPA
type: Organization

Siska Dwi Aryani Sardimin
type: Person
given name: Siska Dwi Aryani
family name: Sardimin

http://digilib.unila.ac.id/id/document/7013
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http://digilib.unila.ac.id/id/document/7014
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http://digilib.unila.ac.id/id/document/7021
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http://digilib.unila.ac.id/id/document/7025
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http://digilib.unila.ac.id/id/document/7026
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http://digilib.unila.ac.id/id/document/7029
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http://digilib.unila.ac.id/id/document/7030
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7031
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http://digilib.unila.ac.id/id/document/7032
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http://digilib.unila.ac.id/id/document/7033
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http://digilib.unila.ac.id/id/document/7034
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http://digilib.unila.ac.id/id/document/7035
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http://digilib.unila.ac.id/id/document/7036
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http://digilib.unila.ac.id/id/document/7037
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http://digilib.unila.ac.id/id/document/7038
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7039
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http://digilib.unila.ac.id/id/document/7040
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http://digilib.unila.ac.id/id/document/7046
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http://digilib.unila.ac.id/id/document/7047
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7049
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7050
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7052
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7054
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7055
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http://digilib.unila.ac.id/id/document/7056
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http://digilib.unila.ac.id/id/document/7059
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http://digilib.unila.ac.id/id/document/7061
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http://digilib.unila.ac.id/id/document/7062
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http://digilib.unila.ac.id/id/document/7063
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http://digilib.unila.ac.id/id/document/7064
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http://digilib.unila.ac.id/id/document/7065
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http://digilib.unila.ac.id/id/document/7066
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http://digilib.unila.ac.id/id/document/7067
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http://digilib.unila.ac.id/id/document/7068
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http://digilib.unila.ac.id/id/document/7069
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http://digilib.unila.ac.id/id/document/7070
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http://digilib.unila.ac.id/id/document/7071
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http://digilib.unila.ac.id/id/document/7072
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7073
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7074
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/id/document/7075
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http://digilib.unila.ac.id/id/document/7080
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http://digilib.unila.ac.id/id/document/7081
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http://digilib.unila.ac.id/id/document/7082
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http://digilib.unila.ac.id/id/document/7083
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http://digilib.unila.ac.id/id/document/7133
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http://digilib.unila.ac.id/id/document/7134
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http://digilib.unila.ac.id/id/document/7135
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http://digilib.unila.ac.id/id/document/7136
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label: SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210) (Other)
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http://digilib.unila.ac.id/115/
title: HTML Summary of #115 SINTESIS DAN KARAKTERISASI SERTA UJI PENDAHULUAN AKTIVITAS ANTIKANKER BEBERAPA SENYAWA ORGANOTIMAH(IV) 3-NITROBENZOAT TERHADAP SEL LEUKEMIA L-1210 (SYNTHESIS, CHARACTERIZATION, AND IN VITRO ANTICANCER ACTIVITY OF SOME ORGANOTIN(IV) 3-NITROBENZOAT COMPOUNDS AGAINST LEUKEMIA CELL L-1210)
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primary topic: http://digilib.unila.ac.id/id/eprint/115

Q Science (General)
type: Concept

QD Chemistry
type: Concept