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primary topic: http://digilib.unila.ac.id/id/eprint/20817

http://digilib.unila.ac.id/id/eprint/20817
type: Article
title: EFEK PEMBERIAN EKSTRAK ETANOL 96% BAWANG PUTIH (Allium sativum L.) TERHADAP KADAR HIGH DENSITY LIPOPROTEIN (HDL) PADA TIKUS PUTIH (Rattus novergicus) JANTAN GALUR Sprague dawley YANG DIBERI PAKAN TINGGI LEMAK
abstract: Dislipidemia adalah suatu kelainan metabolisme lemak dalam tubuh dimana tubuh tidak dapat menjalankan fungsi normalnya akibat kadar lemak yang berlebihan. Kelainan ini dapat memicu terjadinya berbagai penyakit kardiovaskular, seperti penyakit jantung dan stroke. Terdapat kandungan aktif dalam bawang putih yang menunjukkan efek antikolesterol yang dapat mengurangi resiko terjadinya dislipidemia. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak 96% etanol bawang putih terhadap peningkatan kadar kolesterol HDL pada tikus yang diberikan pakan tinggi lemak. Penelitian ini dilakukan selama 28 hari menggunakan 25 tikus putih (Rattus novergicus) jantan galur Sprague Dawley yang dibagi menjadi 5 kelompok dengan 5 ekor tikus pada tiap kelompok. Kelompok kontrol negatif (N) diberikan pakan standar. Kelompok kontrol positif (KT) diberikan diet tinggi lemak secara intermitten. Kelompok P1, P2 dan P3 diberikan diet tinggi lemak intermitten ditambah ekstrak bawang putih berturut-turut sebesar 0.5 ml, 0.025 ml, dan 0.1 ml. Uji One-Way ANOVA menunjukkan p<0.05 (p=0.041). Uji post hoc pada KT-P1 (p=0.182) dan KT-P3 (p=0.603) tidak menunjukkan perbedaan rerata yang bermakna. N-KT (p=0.034) dan KT-P2 (p=0.060) menunjukkan perbedaan rerata yang bermakna. Kesimpulan dari penelitian ini adalah pemberian ekstrak bawang putih secara statistik tidak menunjukkan hasil yang signifikan terhadap peningkatan kadar kolesterol HDL. Kata Kunci: Dislipidemia, bawang putih, kadar kolesterol HDL. Dyslipidemia is a condition in which the body suffer from abnormal fat metabolism, and cannot continue its normal functions which is caused by intolerable high amount of fat in the body. This anomaly may trigger the occurrence of cardiovascular disease, such as heart disease and stroke. There are active compounds found in garlic that shows anticholesterol effect that is able to decrease the risk of dyslipidemia. This research was conducted to study the effect of 96% ethanol garlic extract o…
date: 2015-06-22
status: published
author list: authors
type: EPrint
type: OtherEPrint
is part of: repository
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Fakultas Kedokteran
type: Organization

1118011135 Topaz Kautsar Tritama
type: Person
given name: 1118011135
family name: Topaz Kautsar Tritama

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http://digilib.unila.ac.id/id/document/1586403
type: Document
label: EFEK PEMBERIAN EKSTRAK ETANOL 96% BAWANG PUTIH (Allium sativum L.) TERHADAP KADAR HIGH DENSITY LIPOPROTEIN (HDL) PADA TIKUS PUTIH (Rattus novergicus) JANTAN GALUR Sprague dawley YANG DIBERI PAKAN TINGGI LEMAK (Other)
is version of: http://digilib.unila.ac.id/id/document/1586175
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issmall thumbnail version of: http://digilib.unila.ac.id/id/document/1586175
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http://digilib.unila.ac.id/20817/
title: HTML Summary of #20817 EFEK PEMBERIAN EKSTRAK ETANOL 96% BAWANG PUTIH (Allium sativum L.) TERHADAP KADAR HIGH DENSITY LIPOPROTEIN (HDL) PADA TIKUS PUTIH (Rattus novergicus) JANTAN GALUR Sprague dawley YANG DIBERI PAKAN TINGGI LEMAK
format: text/html
primary topic: http://digilib.unila.ac.id/id/eprint/20817

RS Pharmacy and materia medica
type: Concept