?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PENGARUH+PEMBERIAN+TEMPE+TERHADAP+GAMBARAN+HISTOPATOLOGI+HATI+MENCIT+(Mus+musculus+L.)+OBES&rft.creator=Huzaimah%2C+(121801072)&rft.subject=RA0421+Public+health.+Hygiene.+Preventive+Medicine&rft.description=Latar+belakang%3A+Obesitas+masih+menjadi+masalah+kesehatan+di+dunia%2C+termasuk+di+Indonesia.+Obesitas+merupakan+salah+satu+faktor+risiko+penyakit+Nonalcoholic+Fatty+Liver+Disease+(NAFLD).+Salah+satu+upaya+untuk+mengatasi+obesitas+adalah+dengan+pemberian+tempe.%0D%0ATujuan%3A+Mengetahui+pengaruh+pemberian+tempe+terhadap+gambaran+histopatologi+hati+mencit+(Mus+musculus+L.)+obes.%0D%0AMetode%3A+Penelitian+ini+dilakukan+menggunakan+eksperimental+laboratorium.+Terdapat+4+kelompok+perlakuan%2C+yaitu+K%CB%97%2C+K%2B%2C+P1%2C+dan+P2+dengan+lama+percobaan+selama+28+hari.+Uji+statistik+yang+digunakan+adalah+uji+non+parametrik%2C+yaitu+uji+Kruskal%CB%97Wallis+untuk+menguji+pengaruh+pemberian+tempe+terhadap+gambaran+histopatologi+hati+mencit+(Mus+musculus+L.)+obes+dilanjutkan+dengan+uji+Mann%CB%97Whitney+untuk+mengetahui+perbedaan+gambaran+histopatologi+hati+mencit+(Mus+musculus+L.)+antar+kelompok+perlakuan.%0D%0AHasil%3A+Hasil+dari+uji+Kruskal%CB%97Wallis+didapatkan+p%3D0%2C000+sehingga+pada+K%CB%97+tidak+terlihat+perlemakan+hati%2C+sedangkan+pada+K%2B+terlihat+perlemakan+hati+(p%3D0%2C001)%2C+dan+pada+P1+serta+P2+terlihat+perbaikan+derajat+perlemakan+hati+(p%3D0%2C027+dan+p%3D0%2C004).%0D%0ASimpulan%3A+Terdapat+pengaruh+pemberian+tempe+terhadap+gambaran+histopatologi+hati+mencit+(Mus+musculus+L.)+obes.%0D%0AKata+kunci%3A+gambaran+histopatologi+hati%2C+obesitas%2C+tempe%0D%0A%0D%0A%0D%0AABSTRAK+BAHASA+INGGRIS%0D%0A%0D%0ABackground%3A+Obesity+still+becomes+health+problem+in+the+world%2C+including+Indonesia.+Obesity+is+one+of+the+risk+factor+of+Nonalcoholic+Fatty+Liver+Disease+(NAFLD).+One+of+the+efforts+to+solve+obesity+is+by+giving+tempe+because+it+contains%2C+Polyunsaturated+Fatty+Acid+(PUFA)+functioning+as+decreasing+blood+cholesterol.%0D%0AThe+objective%3A+Was+to+know+the+effect+of+tempe+against+liver+histopathological+appearance+of+obese+mice+(Mus+musculus+L.).%0D%0AMethods%3A+This+research+was+carried+out+using+laboratory+experiment.+There+were+4+groups+of+treatment%2C+they+were+K%CB%97%2C+K%2B%2C+P1%2C+and+P2+with+the+period+of+treatment+for+28+days.+Non+parametric+statistic+with+Kruskal%CB%97Wallis+test+was+applied+to+test+the+effect+of+tempe+against+liver+histopathological+appearance+of+obese+mice+(Mus+musculus+L.)+continued+with+Mann%CB%97Whitney+test+was+applied+to+know+the+difference+of+liver+histopathological+appearance+of+mice+(Mus+musculus+L.)+on+the+group%E2%80%99s+treatment.%0D%0AResults%3A+The+result+of+Kruskal%CB%97Wallis+test+gained+p%3D0%2C000+so+there+was+no+fatty+liver+on+K%CB%97+while+all+the+mice+had+fatty+liver+on+K%2B+(p%3D0%2C001)+and+there+were+improvement+of+fatty+liver+degree+on+P1+and+P2+(p%3D0%2C027+and+p%3D0%2C004).%0D%0AConclusion%3A+There+was+the+effect+of+tempe+against+liver+histopathological+appearance+of+obese+mice+(Mus+musculus+L.).%0D%0AKeywords%3A+liver+histopathological+appearance%2C+obesity%2C+tempe&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2016-02-19&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F21412%2F1%2FABSTRAK%2520BAHASA%2520INGGRIS%2520%2526%2520INDONESIA.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F21412%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F21412%2F3%2FSKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++Huzaimah%2C+(121801072)++(2016)+PENGARUH+PEMBERIAN+TEMPE+TERHADAP+GAMBARAN+HISTOPATOLOGI+HATI+MENCIT+(Mus+musculus+L.)+OBES.++FAKULTAS+KEDOKTERAN%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F21412%2F