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primary topic: http://digilib.unila.ac.id/id/eprint/2345

http://digilib.unila.ac.id/id/eprint/2345
type: Article
title: PENGARUH PEMBERIAN EKSTRAK BUAH MAHKOTA DEWA (Phaleria macrocarpa) TERHADAP GAMBARAN HISTOPATOLOGIS HEPAR TIKUS PUTIH (Rattus Norvegicus) GALUR Sprague dawley YANG DIINDUKSI 7,12-DYMETHYLBENZ(α)ANTHRACENE (DMBA)
abstract: Mahkota dewa (Phaleria macrocarpa) merupakan salah satu tanaman yang berasal dari Pulau Papua namun dapat hidup dengan baik di tempat lainnya. Dia dilaporkan dilaporkan memiliki berbagai aktivitas biologi seperti hepatoprotektor. Phaleria macrocarpa (PM) mengandung flavonoid dan polifenol yang dapat menetralkan radikal bebas karena aktivitas antioksidan dan antiinflamasinyanya. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak etanol 70% buah mahkota dewa. Pada penelitian ini, 25 tikus dibagi dalam 5 kelompok dan diberi perlakuan selama 14 hari. K1 (hanya diberi aquades), K2 (hanya diberi DMBA 30 mg/kgBB), K3 (diberi DMBA 30 mg/kgBB ekstrak PM 24 mg), K4 (diberi DMBA 30 mg/kgBB dan ekstrak PM 48 mg), dan K5 (diberi DMBA 30 mg/kgBB dan ekstrak PM 96 mg). Hasil penelitian menunjukkan total rerata inflamasi pada K1 yaitu 1,08; K2: 3,32; K3: 2,92; K4: 2,28; K5: 1,84. Kesimpulan dari penelitian ini yaitu ekstrak mahkota dewa dapat bertindak melawan inflamasi hepar tikus yang diinduksi DMBA yang berkaitan dengan sifat antioksidan dan antiinflamasinya. Kata kunci : antioksidan, dmba, hepar, Phaleria macrocarpa
date: 2014-02-14
status: published
author list: authors
type: EPrint
type: OtherEPrint
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http://digilib.unila.ac.id/id/document/154521
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http://digilib.unila.ac.id/id/document/154522
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http://digilib.unila.ac.id/id/document/154523
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http://digilib.unila.ac.id/id/document/154524
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http://digilib.unila.ac.id/id/document/154526
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http://digilib.unila.ac.id/id/document/154527
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http://digilib.unila.ac.id/id/document/154528
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http://digilib.unila.ac.id/id/document/154530
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http://digilib.unila.ac.id/id/document/154531
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http://digilib.unila.ac.id/id/document/154532
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http://digilib.unila.ac.id/id/document/154534
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http://digilib.unila.ac.id/id/document/154535
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http://digilib.unila.ac.id/id/document/154537
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http://digilib.unila.ac.id/id/document/154540
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http://digilib.unila.ac.id/id/document/154723
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http://digilib.unila.ac.id/id/document/154724
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http://digilib.unila.ac.id/id/document/154725
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http://digilib.unila.ac.id/id/document/154755
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http://digilib.unila.ac.id/id/document/154759
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http://digilib.unila.ac.id/id/document/154772
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http://digilib.unila.ac.id/id/document/154773
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http://digilib.unila.ac.id/id/document/154774
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http://digilib.unila.ac.id/id/document/154775
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http://digilib.unila.ac.id/id/document/154776
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http://digilib.unila.ac.id/id/document/154777
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http://digilib.unila.ac.id/id/document/154778
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http://digilib.unila.ac.id/id/document/154779
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http://digilib.unila.ac.id/id/document/154780
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http://digilib.unila.ac.id/2345/
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R Medicine (General)
type: Concept