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PENGARUH PEMBERIAN EKSTRAK ETANOL KULIT PISANG AMBON DAN KULIT PISANG KEPOK TERHADAP KADAR KOLESTEROL TOTAL TIKUS PUTIH JANTAN GALUR SPRAGUE DAWLEY THE INFLUENCE OF GIVING ETHANOLIC EXTRACT OF AMBON FRUIT PEEL AND KEPOK FRUIT PEEL TO THE TOTAL CHOLESTEROL LEVEL IN THE MALE RATS FROM SPRAGUE DAWLEY STRAIN
Tingginya kolesterol plasma merupakan salah satu faktor resiko terbesar yang berkontribusi pada prevalensi dan beratnya penyakit kardiovaskuler. Bagian tanaman pisang yang berpotensi menurunkan kolesterol adalah kulit pisang, Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol kulit pisang ambon dan kulit pisang kepok terhadap kadar kolesterol total pada tikus putih jantan galur Sprague Dawley. Dalam penelitian ini digunakan metode eksperimental pre dan post-test design. Subjek penelitian berupa tikus galur Sprague Dawley sebanyak 27 ekor. Kelompok K1 (diet standar), kelompok K2 (diet standar ditambah ekstrak etanol kulit pisang ambon), kelompok K3 (diet standar ditambah ekstrak etanol kulit pisang kepok). Nyimas Annissa Mutiara Andini Sebelumnya, kelompok K1 Dan K2 diberikan diet tinggi lemak dan fruktosa 60% selama 14 hari. Dari hasil penelitian didapatkan kadar kolesterol kontrol (69,00 ± 9,26), penurunan kadar kolesterol total kelompok K2 (71,00 ± 4,12 menjadi 68,00 ± 5,07), dan penurunan kadar kolesterol total kelompok K3 (79,00 ± 3,80 menjadi 68,00 ±3,12.). Uji normalitas yang digunakan yaitu shapiro-wilk (p>0,05). Analisis data dilakukan dengan uji t berpasangan (p<0,05) pada kelompok K2 nilai p=0,003 dan pada kelompok K3 nilai p<0,001. Berdasarkan hasil tersebut dapat disimpulkan bahwa pemberian ekstrak etanol kulit pisang ambon dan kulit pisang kepok memiliki pengaruh terhadap kadar kolesterol total tikus putih jantan galur Sprague Dawley. Kata kunci : ekstrak etanol kulit pisang ambon, ekstrak etanol kulit pisang kepok, kadar kolesterol total High plasma cholesterol level is one of the major risk factor that contribute to the prevalence and heaviness of cardiovascular disease. This research is aimed to know the influence of giving ethanolic extract of ambon banana fruit peel and kepok banana fruit peel to the total cholesterol level in the male rats from Sprague Dawley strain. It uses pre and posttest experimental design. The subjects are 27 male Sprague Dawley strain rats. There are group K1 (standard diet), group K2 (standard diet plus ethanolic extract of ambon banana fruit peel), and group K3 (standard diet plus ethanolic extract of kepok banana fruit peel). Before, group K2 and K3 have given a high fat diet plus fructose liquid 60% for 14 days. From the results, we got the K1 control total cholesterol level (69,00 ± 9,26), decreased of total cholesterol level in group K2 (from 71,00 ± 4,12 to 68,00 ± 5,07), and decreased of total cholesterol level in group K3 (from 79,00 ± 3,80 to 68,00 ±3,12). Datas of total cholesterol level before and after treatment of ethanolic extract of ambon and kepok fruit peel are analyzed with paired t test (p<0,05), group K2 p=0,003 and for group K3 p<0,001. We can conclude that giving ethanolic extract of ambon banana fruit peel and kepok banana fruit peel influence the total cholesterol level in the male rats from Sprague Dawley strain. Keywords : ethanolic extract of ambon banana fruit peel, ethanolic extract of kepok banana fruit peel, total cholesterol level
PENGARUH PEMBERIAN EKSTRAK ETANOL KULIT PISANG AMBON DAN KULIT PISANG KEPOK TERHADAP KADAR KOLESTEROL TOTAL TIKUS PUTIH JANTAN GALUR SPRAGUE DAWLEY THE INFLUENCE OF GIVING ETHANOLIC EXTRACT OF AMBON FRUIT PEEL AND KEPOK FRUIT PEEL TO THE TOTAL CHOLESTEROL LEVEL IN THE MALE RATS FROM SPRAGUE DAWLEY STRAIN (File PDF)
PENGARUH PEMBERIAN EKSTRAK ETANOL KULIT PISANG AMBON DAN KULIT PISANG KEPOK TERHADAP KADAR KOLESTEROL TOTAL TIKUS PUTIH JANTAN GALUR SPRAGUE DAWLEY THE INFLUENCE OF GIVING ETHANOLIC EXTRACT OF AMBON FRUIT PEEL AND KEPOK FRUIT PEEL TO THE TOTAL CHOLESTEROL LEVEL IN THE MALE RATS FROM SPRAGUE DAWLEY STRAIN (Other)
HTML Summary of #2442 PENGARUH PEMBERIAN EKSTRAK ETANOL KULIT PISANG AMBON DAN KULIT PISANG KEPOK TERHADAP KADAR KOLESTEROL TOTAL TIKUS PUTIH JANTAN GALUR SPRAGUE DAWLEY THE INFLUENCE OF GIVING ETHANOLIC EXTRACT OF AMBON FRUIT PEEL AND KEPOK FRUIT PEEL TO THE TOTAL CHOLESTEROL LEVEL IN THE MALE RATS FROM SPRAGUE DAWLEY STRAIN
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