%A 1418011167 Putu Arya Laksmi Amrita Kirana
%T HUBUNGAN NILAI MEAN PLATELET VOLUME (MPV) DAN PLATELET DISTRIBUTION WIDTH (PDW) TERHADAP JUMLAH TROMBOSIT PADA PASIEN DEMAM BERDARAH DENGUE DI RS URIP SUMOHARJO
%X Background: Dengue Hemorrhagic Fever (DHF) is one of the most common tropical infectious diseases in Indonesia caused by dengue virus, characterized by thrombocytopenia. The mechanism of thrombocytopenia is thought to be caused by depression of megakaryocyte function. There are several platelet indices known as platelet activation indicator, Mean Platelet Volume (MPV), and Platelet Distribution Width (PDW).
Methods: The design of this study was correlative cross sectional analysis of 38 dengue patients in Urip Sumoharjo Hospital with age range 15 - 60 years. Data taken in the form of primary data that is result of blood examination of DHF patient. The variables of this research are MPV value and PDW value and platelet count of DHF patients
Results: The mean platelet count of 82,750 + 27,710 cells / mm3 and MPV content has an average of 10.9 ?m3 and rete of PDW level of 15,6 fl. Pearson correlative test results of MPV to platelet count are 0.001 (p-value <0.05) and r value of -0.5. Spearman test result of PDW value to Number of Platelet is 0,021 (p-value <0,05) and r value equal to -0,375.
Conclusion: There is a negative correlation between MPV value and platelet count with moderate correlation strength, and there is weak correlation between PDW value and platelet count.
Keywords: Dengue hemorrhagic fever, mean platelet volume, platelet distribution width, thrombocytopenia
%D 2018
%C Universitas Lampung
%R 1418011167
%I Fakultas Kedokteran
%L eprints30179