?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PENGARUH+PEMBERIAN+EKSTRAK+JAHE+MERAH++(Zingiber+officinale+var+rubrum)+TERHADAP+PENURUNAN+KADAR+ASAM+URAT+DARAH+PADA+MENCIT+OBESITAS++&rft.creator=NADIYA+DEWI+KUSNADI+%2C+1418011142&rft.subject=RA+Public+aspects+of+medicine&rft.description=Latar+belakang%3A+Obesitas+merupakan+salah+satu+masalah+kesehatan+yang+terjadi%0D%0Adi+Indonesia.+Pada+penderita+obesitas+akan+mengalami+beberapa+keadaan+seperti%0D%0Apeningkatan+kadar+asam+urat+darah+(hiperurisemia).+Seseorang+dikatakan%0D%0Ahiperurisemia+jila+memiliki+kadar+asam+urat+darah+%3E7+mg%2FdL+pada+laki-laki+dan+%3E6%0D%0Amg%2FdL+pada+wanita.+Keadaan+hiperursemia+ini+akan+menimbulkan+gejala%2C+salah%0D%0Asatunya+nyeri+pada+persendian.+Jahe+merah+(Zingiber+officinale+var+rubrum)%0D%0Amerupakan+salah+satu+rempah+yang+banyak+digunakan+di+Indonesia.+Didalam+jahe%0D%0Amerah+terkandung+senyawa+aktif+yaitu+gingerol+dan+6-shogaol+yang+dapat%0D%0Amenurunkan+kadar+asam+urat+dalam+darah.%0D%0AMetode%3A+Jenis+penelitian+ini+menggunakan+metode+penelitian+eksperimental%0D%0Adengan+teknik+pengambilan+sampel+adalah+post-test+control+design+group.%0D%0APenelitian+dilaksanakan+pada+Oktober+sampai+November+2017%2C+bertempat+di%0D%0AFakultas+Kedokteran+Universitas+Lampung.+Sampel+yang+berhasil+didapatkan%0D%0Aadalah+20+ekor+mencit.+%0D%0AHasil+%3A+Hasil+penelitian+yang+dilakukan+terdapat+pengaruh+pemberian+ekstrak+jahe%0D%0Amerah+terhadap+penurunan+kadar+asam+urat+darah+pada+mencit+obesitas.+Uji%0D%0Anormalitas+didapatkan+p%3D0%2C490+untuk+kontrol+negatif%2C+p%3D0%2C705+untuk+kontrol%0D%0Apositif%2C+p%3D0%2C377+pada+kelompok+perlakuan+1+dan+p%3D0%2C928+pada+kelompok%0D%0Aperlakuan+2.+Dimana+artinya+data+terdistribusi+normal%2C+selanjutnya+data+di+uji%0D%0Ahomogenitas+dengan+Levene+hasilnya+p%3D0%2C039+dan+dilanjutkan+dengan+uji+Anova%0D%0Adan+didapatkan+p%3D0%2C000.%0D%0ASimpulan%3A+Terdapat+pengaruh+pemberian+ekstrak+jahe+merah+(Zingiber%0D%0Aofficinale+var+rubrum)+terhadap+penurunan+kadar+asam+urat+darah+pada+mencit%0D%0Aobesitas.+%0D%0A+%0D%0AKata+kunci+%3A+hiperurisemia%2C+obesitas%2C+jahe+merah+%0D%0A%0D%0A%0D%0AABSTRACT%0D%0A%0D%0A%0D%0A%0D%0A+%0D%0ABackground%3A+Obesity++is+the+one+of+the+health+problems+that+occur+in+Indonesia.%0D%0AObesity%E2%80%99s+patient+will+suffer+more+condition+like+increasing+blood+uric+acid+levels%0D%0A(hyperuricemia).+People+who+suffer+hyperuricemia+will+have+blood+uric+acid+level%0D%0Amore+than+7+mg%2Fdl+for+men+and+6+mg%2Fdl+for+women.+Hyperuricemia%E2%80%99s+condition%0D%0Awill+make+symptomps+like+paint+in+the+joints.+Red+ginger+(Zingiber+officinale+var%0D%0Arubrum)+is+the+one+of+most+used+herbs+in+Indonesia.+In+the+red+ginger+contain%0D%0Aactive+compounds+that+called+gingerol+and+6-shogaol+which+decrease+blood+uric%0D%0Aacid+levels+in+blood.%0D%0AMethod%3A+This+research+use+experimental+method+with+post-test+control+design%0D%0Agroup+as+a+technique+sampling.+The+study+hold+from+January+until+February+2018%2C%0D%0Alocated+in+Faculty+of+medicine%2C+Lampung+University.+The+sampling+used+20+mices.%0D%0AResult%3A+The+result+is+there+is+an+effect+of+red+ginger+extract+to+decrease+blood+uric%0D%0Aacid+levels+in+obesity+mice.+Normality+test+results+obtained+p+value+%3D+0.490+in%0D%0Anegative+control%2C+p+value+%3D+0.705+in+positive+control%2C+p+value+%3D+0.377+in+first%0D%0Atreatment+group+and+p+value+%3D+0.928+in+second+treatment+group.+Which+means+the%0D%0Adata+are+normally+distributed.+Homogenity+test+with+Leven's+got+significance+value%0D%0A0%2C039+and+continued+with+test+of+anova+then+got+result+of+significance+0.000.%0D%0AConclusion%3A+There+is+an+effect+of+red+ginger+extract+(Zingiber+officinale+var%0D%0Arubrum)+to+decrease+blood+uric+acid+levels+on+obesity+mice.%0D%0A%0D%0AKeyword%3A+hyperuricemia%2C+obesity%2C+red+ginger++&rft.publisher=UNIVERSITAS+LAMPUNG+&rft.date=2018-02-23&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F32473%2F1%2FABSTRAK%2520%2528INGGRIS%2520%2526%2520INDONESIA%2529.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F32473%2F17%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F32473%2F18%2FSKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++NADIYA+DEWI+KUSNADI+%2C+1418011142++(2018)+PENGARUH+PEMBERIAN+EKSTRAK+JAHE+MERAH+(Zingiber+officinale+var+rubrum)+TERHADAP+PENURUNAN+KADAR+ASAM+URAT+DARAH+PADA+MENCIT+OBESITAS.++UNIVERSITAS+LAMPUNG+%2C++FAKULTAS+KEDOKTERAN+.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F32473%2F