?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PREDIKSI+METILASI+PADA+SEQUENCE+PROTEIN+ARGININE%0D%0A%0D%0AMENGGUNAKAN+RANDOM+FOREST&rft.creator=WIWIT+MUDYANINGSIH%2C+1517051225&rft.subject=000+Ilmu+komputer%2C+informasi+dan+pekerjaan+umum&rft.subject=003+Sistem-sistem&rft.description=One+of+the+popular+Post-Translational+Modification+(PTM)+is+methylation.%0D%0AMethylation+can+occur+in+the+amino+acid+arginine.+Arginine+methylation+carries%0D%0Aout+and+regulates+several+important+biological+functions%2C+including+gene%0D%0Aregulation+and+signal+transduction.+Experimental+identification+of+arginine%0D%0Amethylation+sites+is+a+daunting+task+because+it+is+expensive+and+requires+more+time%0D%0Aand+energy.+Therefore+reliable+predictions+play+an+important+task+in+predicting%0D%0Aquickly+and+identifying+possible+methylation+sites+in+proteomes.+In+the+study+using%0D%0Athe+Random+Forest+method+which+is+one+of+the+data+mining+techniques+for%0D%0Aclassification%2C+and+previously+performed+feature+extraction%2C+feature+extraction%0D%0Aused+is+CTD%2C+PseAAc%2C+AA+index+and+QSO+by+using+the+protr+and+bioseqclass%0D%0Apackages+in+the+r+programming+language.+and+obtained+138+variables.+This+study%0D%0Ahas+3+types+of+experiments%2C+training+set+in+1%3A1+ratio%2C+Testing+data+set+and%0D%0AIndependent+data+set.+The+prediction+perform+reasonably+well+with+the+highest%0D%0Aaccuracy+obtained+in+the+Independent+Data+experiment+that+is+equal+to+98.08%25%2C%0D%0Awhile+for+Training+Data+the+ratio+of+1%3A+1+gets+93.76%25+and+Testing+gets+the+lowest%0D%0Aaccuracy+that+is+equal+to+80.32%25.%0D%0A%0D%0AKeywords%3A+Methylation%2C+Random+Forest%2C+Prediction%2C+Arginine%2C+Feature%0D%0AExtraction%2C+Machine+Learning%0D%0ASalah+satu+Post-Translational+Modification+(PTM)+yang+populer+adalah+metilasi.+Metilasi+dapat+terjadi+dalam+asam+amino+arginine.+Metilasi+arginin+melakukan+dan%0D%0Amengatur+beberapa+fungsi+biologis+penting%2C+termasuk+regulasi+gen+dan+transduksi%0D%0Asinyal.+Identifikasi+eksperimental+situs+arginine+metilasi+adalah+tugas+yang+berat%0D%0Adikarenakan+mahal+serta+memerlukan+waktu+dan+tenaga+yang+lebih.+Oleh+karena%0D%0Aitu+prediksi+yang+handal+memainkan+tugas+penting+dalam+memprediksi+dengan%0D%0Acepat+dan+mengidentifikasi+kemungkinan+situs+metilasi+di+proteomes.+Pada%0D%0Apenelitian+menggunakan+metode+Random+forest+yang+merupakan+salah+satu+teknik%0D%0Adata+mining+untuk+melakukan+klasifikasi%2C+serta+sebelumnya+dilakukan+feature%0D%0Aextraction%2C+feature+extraction+yang+digunakan+yaitu+CTD%2C+PseAAc%2C+AA+index+dan%0D%0AQSO+dengan+menggunakan+package+protr+dan+bioseqclass+pada+bahasa%0D%0Apemrograman+R+Programming.%2C+dan+didapatkan+138+variabel.+Penelitian+ini%0D%0Amemiliki+3+jenis+eksperimen+yaitu+data+Rasio+1%3A1%2C+Testing+dan+Independent%0D%0Adataset.+Prediksi+ini+berkinerja+yang+cukup+baik+dengan+didapatkan+akurasi%0D%0Atertinggi+pada+percobaan+Data+Independent+yaitu+sebesar+98%2C08+%25%2C+sedangkan%0D%0Auntuk+data+Training+Rasio+1%3A1+mendapatkan+93%2C76+%25+dan+Testing+mendapat%0D%0Aakurasi+terendah+yaitu+sebesar+80%2C32+%25.%0D%0AKata+kunci%3A+Metilasi%2C+Random+Forest%2C+Prediksi%2C+Arginine%2C+Ekstraksi+Fitur%2C%0D%0A%0D%0AMachine+Learning&rft.publisher=FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM&rft.date=2019&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F57732%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F57732%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F57732%2F3%2FSKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++WIWIT+MUDYANINGSIH%2C+1517051225++(2019)+PREDIKSI+METILASI+PADA+SEQUENCE+PROTEIN+ARGININE+MENGGUNAKAN+RANDOM+FOREST.++FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F57732%2F