?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PERBEDAAN+DAYA+ANTIBAKTERI+EKSTRAK+BIJI+HIJAU+DAN%0D%0ASANGRAI+KOPI+ROBUSTA+(Coffea+canephora)+TERHADAP%0D%0APERTUMBUHAN+BAKTERI+METHICILIN-RESISTANT%0D%0AStaphylococcus+aureus+SECARA+IN+VITRO&rft.creator=Farhana+fitri+Amalia%2C+1518011054&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Latar+Belakang%3A+Methicilin-resistant+Staphylococcus+aureus+(MRSA)+merupakan%0D%0Asalah+satu+jenis+bakteri+resisten+yang+menjadi+masalah+kesehtan+dunia.+Prevalensi%0D%0AMRSA+terus+meningkat+baik+sebagai+penyakit+nosokomial+maupun+penyakit%0D%0Akomunitas%2C+sehingga+perlu+dikembangkannya+senyawa+antibakteri+baik+sintetis%0D%0Amaupun+alami.+Kopi+robusta+(Coffea+canephora)+memiliki+banyak+senyawa+aktif%0D%0Ayang+bersifat+antibakteri%2C+namun+proses+penyangraian+menyebabkan+berbagai%0D%0Aperubahan+pada+senyawa+aktif+tersebut.+Penelitian+bertujuan+untuk+mengetahui%0D%0Aperbedaan+daya+antibakteri+ekstrak+biji+hijau+dan+sangrai+kopi+robusta+terhadap%0D%0AMRSA.%0D%0AMetode%3A+Penelitian+ini+menggunakan+desain+penelitian+posttest+only+control+group%0D%0Adesign+dan+menguji+aktivitas+antibakteri+ekstrak+biji+hijau+dan+sangrai+kopi+robusta%0D%0Adengan+konsentrasi+masing-masing+50%25%2C+25%25%2C+12%2C5%25%2C+dan+6%2C25%25+terhadap+bakteri%0D%0AMRSA+dengan+mengukur+diameter+zona+hambat%2C+konsentrasi+hambat+minimal%0D%0A(KHM)%2C+dan+konsentrasi+bunuh+minimal+(KBM)+serta+perbedaan+antara+keduanya.%0D%0AHasil%3A+Hasil+penelitian+menunjukan+adanya+aktivitas+antibakteri+ekstrak+biji+hijau%2C%0D%0Adengan+rerata+diameter+zona+hambat+berkisar+antara+16%2C91+mm+hingga+6%2C47+mm%2C%0D%0AKHM+pada+konsentrasi+6%2C25%25+serta+KBM+pada+konsentrasi+12%2C5%25.+Pada+ekstrak%0D%0Abiji+sangrai+rerata+diameter+zona+hambat+berkisar+antara+14%2C89+mm+hingga+5%2C00%0D%0Amm%2C+KHM+pada+konsentrasi+6%2C25%25+serta+KBM+pada+konsentrasi+25%25.+Tidak%0D%0Aperbedaan+KHM+dan+diameter+zona+hambat+yang+bermakna+secara+statistik+namun%0D%0Aterdapat+perbedaan+pada+KBM.%0D%0ASimpulan%3A+Tidak+terdapat+perbedaan+daya+antibakteri+antara+ekstrak+biji+hijau+dan%0D%0Asangrai+kopi+robusta+terhadap+pertumbuhan+bakteri+MRSA%0D%0AKata+Kunci%3A+aktivitas+antibakteri%2C+methicilin-resistant+staphylococcus+aureus%2C%0D%0Akopi+robusta%0D%0A%0D%0ABackground%3A+Methicilin-resistant+Staphylococcus+aureus+(MRSA)+is+one+of+the%0D%0Aresistant+bacteria+that+is+a+global+health+problem.+The+prevalence+of+MRSA%0D%0Acontinues+to+increase+as+a+nosocomial+and+community+disease%2C+it+is+necessary+to%0D%0Adevelop+antibacterial+compounds+both+synthetic+and+natural.+Robusta+coffee%0D%0A(Coffea+canephora)+has+many+active+antibacterial+compounds%2C+but+the+roasting%0D%0Aprocess+causes+various+changes+in+these+compounds.+The+study+aims+to+determine%0D%0Athe+differences+between+the+antibacterial+power+of+robusta+coffee+green+and%0D%0Aroasted+bean+extract+on+MRSA.%0D%0AMethods%3A+This+study+used+a+posttest+only+control+group+design+and+tested+the%0D%0Aantibacterial+activity+of+green+and+roasted+bean+extract+of+robusta+coffee+with%0D%0Aconcentrations+of+50%25%2C+25%25%2C+12.5%25%2C+and+6.25%25+against+MRSA+bacteria+by%0D%0Ameasuring+the+diameter+of+inhibitory+zones%2C+minimum+inhibitory+concentration%0D%0A(MIC)%2C+and+minimum+bactericidal+concentration+(MBC)%2C+as+well+as+the+difference%0D%0Abetween+the+two.%0D%0AResults%3A+The+results+showed+that+there+was+antibacterial+activity+of+green+bean%0D%0Aextract%2C+with+the+average+diameter+of+inhibition+zone+ranging+from+16%2C91+mm+to%0D%0A6%2C47+mm.+The+MIC+obtained+at+concentration+of+6.25%25+and+MBC+at%0D%0Aconcentration+of+12.5%25.+The+average+diameter+of+inhibiton+zone+of+roasted+bean%0D%0Aextract+ranging+from+14%2C89+mm+to+5.00+mm%2C+MIC+obtained+at+concentration+of%0D%0A6.25%25+and+MBC+at+concentration+of+25%25.+No+differences+in+MIC+and+inhibition%0D%0Azone+diameter+are+statistically+significant+but+there+was+differences+in+MBC.%0D%0AConclusion%3A+There+was+no+difference+in+antibacterial+power+between+robusta%0D%0Acoffee+green+and+roasted+bean+extract+on+the+growth+of+MRSA+bacteria.%0D%0AKeywords%3A+antibacterial+activity%2C+methicillin-resistant+staphylococcus+aureus%2C%0D%0Arobusta+coffee.&rft.publisher=Fakultas+Kedokteran+&rft.date=2019-12-26&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F58899%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F58899%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F58899%2F3%2FSKRIPSI%2520TANPA%2520PEMBAHASAN.pdf&rft.identifier=++Farhana+fitri+Amalia%2C+1518011054++(2019)+PERBEDAAN+DAYA+ANTIBAKTERI+EKSTRAK+BIJI+HIJAU+DAN+SANGRAI+KOPI+ROBUSTA+(Coffea+canephora)+TERHADAP+PERTUMBUHAN+BAKTERI+METHICILIN-RESISTANT+Staphylococcus+aureus+SECARA+IN+VITRO.++Fakultas+Kedokteran+%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F58899%2F