?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PERBANDINGAN+KADAR+HORMON+ADIPONEKTIN+ANTARA%0D%0AKALANGAN+PEROKOK+AKTIF+DAN+PASIF%0D%0ADI+WILAYAH+LABUHAN+RATU%2C%0D%0ABANDARLAMPUNG&rft.creator=Pramastha+Candra+Sasmita%2C+1518011046&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Latar+Belakang+%3A+Nikotin+merupakan+senyawa+yang+memiliki+efek+inhibisi%0D%0Aterhadap+kadar+adiponektin+yang+dapat+dijumpai+dalam+plasma+perokok.%0D%0AAdiponektin+adalah+adipositokin+utama+yang+erat+kaitannya+dengan+proses+anti%0D%0Aaterogenik%2C+anti-inflamasi%2C+dan+sentisiasi+insulin.+Kadar+adiponektin+pada+perokok%0D%0Aaktif+memiliki+jumlah+yang+lebih+rendah+dibanding+yang+bukan+perokok.%0D%0APenelitian+ini+bertujuan+untuk+menganalisis+perbandingan+kadar+hormon%0D%0Aadiponektin+antara+perokok+aktif+dengan+pasif+di+wilayah+Labuhan+Ratu%2C+Bandar%0D%0ALampung.%0D%0AMetode+%3A+Penelitian+ini+menggunakan+metode+analitik+komparatif+dengan%0D%0Apendekatan+Cross+Sectional.+Terdapat+sampel+sebanyak+14+sampel%2C+dimana+terdiri%0D%0Aatas+7+sampel+perokok+aktif+dan+7+sampel+perokok+pasif.+Penelitian+dilakukan%0D%0Adengan+menggunakan+kuesioner+pengukuran+antropometri+dan+ELISA+kit+sebagai%0D%0Aalat.+Pada+penelitian+ini+menggunakan+%CE%B1+%3D+0.05.+Analisis+data+menggunakan+uji%0D%0AIndependent+T-test.%0D%0AHasil+%3A+Rerata+kadar+adiponektin+pada+sampel+perokok+aktif+sebesar+8%2C33+%CE%BCg+%2F+ml%2C%0D%0Asedangkan+pada+sampel+perokok+pasif+memiliki+rerata+kadar+adiponektin+sebesar%0D%0A4.77+%CE%BCg+%2F+ml+dan+nilai+rerata+kadar+adiponektin+seluruh+sampel+sebesar+6%2C55+%CE%BCg+%2F%0D%0Aml.+Nilai+p+0%2C097+(p+%3E+0%2C05).+Sebanyak+7+sampel+(50+%25)+dari+perokok+pasif%0D%0Aseluruhnya+memiliki+kadar+adiponektin+yang+lebih+rendah+dari+nilai+rujukan.%0D%0ASedangkan+dari+perokok+aktif+sebanyak+5+sampel+(35%2C7+%25)+memiliki+kadar%0D%0Aadiponektin+yang+lebih+rendah+dari+nilai+rujukan.+Dan+2+sampel+(14%2C3%25)+pada%0D%0Aperokok+pasif+memiliki+kadar+adiponektin+yang+lebih+tinggi+dari+nilai+rujukan.%0D%0AKesimpulan+%3A+Dengan+demikian+tidak+didapatkan+perbedaan+yang+signifikan%0D%0Aantara+kadar+adiponektin+perokok+aktif+dengan+perokok+pasif.+Baik+perokok+aktif%0D%0Amaupun+perokok+pasif+memiliki+kadar+adiponektin+yang+lebih+rendah+dari+nilai%0D%0Anormal+(%3C8.04+%CE%BCg%2FmL)+kecuali+2+(14%2C3+%25)+sampel+pada+perokok+aktif+yang%0D%0Amemiliki+kadar+adiponektin+lebih+tinggi+dari+nilai+rujukan.%0D%0AKata+kunci+%3A+Adiponetkin%2C+Nikotin%2C+Perokok+pasif%0D%0A%0D%0ABackground+%3A+Nicotine+is+a+compound+that+has+an+inhibitory+effect+on+adiponectin%0D%0Alevels+which+can+be+found+in+plasma+smokers.+Adiponectin+is+the+main%0D%0Aadipocytokine+that+is+closely+related+to+the+anti-atherogenic%2C+anti-inflammatory%2C%0D%0Aand+insulin-centric+processes.+Adiponectin+levels+in+active+smokers+have+a+lower%0D%0Anumber+than+non-smokers.+This+study+tried+to+analyze+the+levels+of+adiponectin%0D%0Ahormone+between+passive+active+smokers+in+the+Labuhan+Ratu+area%2C+Bandar%0D%0ALampung.%0D%0AMethods+%3A+This+study+uses+an+analytical+method+with+Cross+Sectional.+A+sample%0D%0Aof+14+samples+was+obtained%2C+which+consisted+of+7+samples+of+active+smokers+and+7%0D%0Asamples+of+passive+smokers.+The+study+was+conducted+using+an+anthropometric%0D%0Ameasurement+questionnaire+and+ELISA+kit+as+a+tool.+In+this+study+using+%CE%B1+%3D+0.05.%0D%0AData+analysis+using+the+Independent+T-test.%0D%0AResults+%3A+The+average+adiponectin+level+in+active+smoker+samples+was+8.33+%CE%BCg+%2F%0D%0Aml%2C+whereas+in+the+passive+smoker+sample+it+had+an+adiponectin+level+of+4.77+%CE%BCg+%2F%0D%0Aml+and+the+average+adiponectin+level+for+the+sample+was+6.55+%CE%BCg+%2F+ml.+P+value+of%0D%0A0.097+(p%3E+%CE%B1).+A+total+of+7+samples+(50%25)+of+passive+smokers+all+has+adiponectin%0D%0Alevels+which+were+lower+than+the+normal+values.+Whereas+5+active+smokers%0D%0A(35.7%25)+has+adiponectin+levels+which+were+lower+than+the+reference+values.+And+2%0D%0Asamples+(14.3%25)+in+passive+smokers+had+higher+adiponectin+levels+than+the%0D%0Areference+value.%0D%0AConclusion+%3A+Thus+there+was+no+significant+difference+between+the+levels+of%0D%0Aadiponectin+in+active+smokers+and+passive+smokers.+Both+active+smokers+and%0D%0Apassive+smokers+has+lower+adiponectin+levels+than+normal+values+(%3C8.04+%CE%BCg+%2F+mL)%0D%0Aexcept+for+2+(14.3%25)+samples+in+active+smokers+who+has+adiponectin+levels+higher%0D%0Athan+the+normal+value.%0D%0AKeywords%3A+Adiponectin%2C+Nicotine%2C+Passive+smoker&rft.publisher=Fakultas+Kedokteran+&rft.date=2019-04-04&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F59509%2F1%2FABSTRAK-ABSTRACT.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F59509%2F2%2FSKRIPSI%2520FULL%2520TEKS.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F59509%2F3%2FSKRIPSI%2520FULL%2520TANPA%2520BAB%2520PEMABHASAN.pdf&rft.identifier=++Pramastha+Candra+Sasmita%2C+15180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