?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=EFEKTIVITAS+EKSTRAK+KULIT+KOPI+ROBUSTA+(Coffea+canephora)%0D%0A%0D%0ASEBAGAI+REPELAN+Aedes+aegypti&rft.creator=JUNDI+FATHAN+MUBINA%2C+1618011133&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Latar+Belakang+%3A+Demam+berdarah+dengue+(DBD)+merupakan+penyakit+infeksi+tropis%0D%0Ayang+disebabkan+oleh+virus+dengue+(DENV)+dengan+gigitan+nyamuk+Aedes+aegypti%0D%0Asebagai+vektor.+Salah+satu+cara+pencegahan+gigitan+nyamuk+adalah+dengan+menggunakan%0D%0Arepelan.+Repelan+yang+umum+digunakan+mengandung+senyawa+DEET.+Walaupun+dinilai%0D%0Acukup+aman%2C+terdapat+beberapa+laporan+yang+menunjukkan+efek+samping+DEET+terhadap%0D%0Amanusia.+Untuk+itu+diperlukan+alternatif+repelan+yang+lebih+aman+namun+tetap+efektif.%0D%0ARepelan+alami+adalah+salah+satu+alternatifnya.+Ekstrak+kulit+kopi+robusta+(Coffea%0D%0Acanephora)+memiliki+kandungan+berbagai+fitokimia+yang+berpotensi+menolak+nyamuk.%0D%0ATujuan+%3A+Mengetahui+efektivitas+ekstrak+kulit+kopi+robusta+(Coffea+canephora)+sebagai%0D%0Arepelan+terhadap+nyamuk+Aedes+aegypti.%0D%0AMetode+%3A+Ini+merupakan+penelitian+dengan+rancangan+acak+lengkap+yang+mengacu+pada%0D%0Auji+efikasi+WHOPES+2009.+Penelitian+dilaksanakan+pada+Januari+2020+hingga+Februari%0D%0A2020.+Lengan+uji+yang+diberikan+etanol+sebagai+kontrol+negatif+dan+repelan+ekstrak+kulit%0D%0A%0D%0Akopi+sebagai+perlakuan+dimasukkan+ke+dalam+5+kurungan+nyamuk+berbeda+yang+masing-%0D%0Amasing+berisi+50+ekor+nyamuk+Aedes+aegypti+lalu+diamati+jumlah+nyamuk+yang+hinggap%0D%0A%0D%0Aselama+30+detik+diulangi+sebanyak+5+kali+(seri+konsentrasi+10%3B+20%3B+30%3B+40%3B+dan+50%25+serta%0D%0Akontrol).+Daya+proteksi+masing-masing+kelompok+perlakuan+dianalisis.%0D%0AHasil+%3A+Analisis+daya+proteksi+menggunakan+uji+Kruskal-Wallis+menunjukkan+ekstrak%0D%0Akulit+kopi+robusta+efektif+sebagai+repelan+Aedes+aegypti+ditandai+dengan+perbedaan%0D%0Asignifikan+(p%3C0%2C05).+Regresi+probit+menunjukkan+dosis+efektif+median+(ED50)+dan+dosis%0D%0Aefektif+maksimum+(ED99)+masing-masing+pada+konsentrasi+12%2C76%25+dan+48%2C55%25.%0D%0ASimpulan+%3A+Ekstrak+kulit+kopi+robusta+(Coffea+canephora)+efektif+sebagai+repelan%0D%0Aterhadap+nyamuk+Aedes+aegypti.%0D%0A%0D%0AKata+kunci+%3A+Aedes+aegypti%2C+daya+proteksi%2C+ekstrak+kulit+kopi%2C+repelan%0D%0ABackground+%3A+Dengue+Hemorrhagic+Fever+(DHF)+is+a+tropical+infectios+disease+caused%0D%0Aby+dengue+virus+(DENV)+with+mosquitos+bite+primarily+by+Aedes+aegypti+as+a+vector.+One%0D%0Away+to+prevent+mosquito+bites+is+to+use+repellent.+DEET+is+one+of+the+most+common%0D%0Arepellent.+Even+though+DEET+is+considered+fairly+safe%2C+there+is+still+concern+about+the%0D%0ADEET+side+effects.+Therefore+a+safer+and+effective+alternative+repellent+is+needed.+Natural%0D%0Arepellent+are+one+of+the+alternative.+Robusta+coffee+(Coffea+canephora)+husk+extract%0D%0Acontains+various+phytochemicals+that+potentially+repel+mosquitos.%0D%0AObjective+%3A+To+assess+the+effectiveness+of+robusta+coffee+(Coffea+canephora)+husk+extract%0D%0Aas+Aedes+aegypti+repellent.%0D%0AMethods+%3A+This+research+is+an+experimental+laboratory+with+a+completely+randomized%0D%0Adesign+based+on+efficacy+test+guideline+of+WHOPES+2009+which+was+conducted+between%0D%0AJanuary+2020+to+February+2020.+The+test+arm+was+given+ethanol+and+repellent+of+robusta%0D%0Acoffee+husk+extract+and+then+put+into+5+differant+cages+that+contains+50+Aedes+aegypti+for%0D%0A30+seconds+to+count+the+number+of+mosquitoes+that+make+a+contact+with+the+test+arm.+The%0D%0Arepellency+effect+results+of+each+group+was+analyzed.%0D%0AResult+%3A+Kruskal-Wallis+test+on+repellency+percentage+shows+that+robusta+coffee+husk%0D%0Aextract+are+effective+as+Aedes+aegypti+repellent.+Probit+regression+show+that+the+median%0D%0Aeffective+dose+(ED50)+and+maximum+effective+dose+(ED99)+is+12.76%25+and+48.55%25%0D%0Arespectively.%0D%0AConclusion+%3A+Robusta+coffee+(Coffea+canephora)+husk+extract+is+effective+as+Aedes%0D%0Aaegypti+repellent.&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2021&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F60134%2F1%2FABSTRAK%2520-%2520Jundi%2520Fathan%2520Mubina.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F60134%2F2%2FFULL%2520SKRIPSI%2520-%2520Jundi%2520Fathan%2520Mubina.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F60134%2F3%2FFULL%2520SKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN%2520-%2520Jundi%2520Fathan%2520Mubina.pdf&rft.identifier=++JUNDI+FATHAN+MUBINA%2C+1618011133++(2021)+EFEKTIVITAS+EKSTRAK+KULIT+KOPI+ROBUSTA+(Coffea+canephora)+SEBAGAI+REPELAN+Aedes+aegypti.++FAKULTAS+KEDOKTERAN%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F60134%2F