creators_name: Humairoh Abdul Kadir Zubaidi, 1718011096
creators_id: humairohzubaidi53@gmail.com
type: other
datestamp: 2022-04-25 01:29:04
lastmod: 2022-04-25 01:29:04
metadata_visibility: show
title: PERBEDAAN KADAR MALONDIALDEHID (MDA) PLASMA TIKUS
PUTIH (Rattus norvegicus) GALUR Sprague dawley YANG TERPAPAR
OBAT NYAMUK BAKAR DENGAN OBAT NYAMUK SPRAY
ispublished: pub
subjects: 610
full_text_status: restricted
abstract: Background: Coil and spray mosquito repellent are the most used type to avoid
mosquito bites. Coil repellent‟s fumes contain active substances and toxic residua
of coil burn, while spray mosquito repellent spread in aerosol form which easily
absorbed by human body. Mosquito repellent‟s active substances will cause free
radical increase in the body which is shown by the increase of malondialdehyde
level. This research objective is to know plasma malondialdehyde level difference
between coil repellent exposed rats and spray mosquito repellent exposed
Methods: This experimental research is done in 30 days to 30 Sprague dawley
strain albino rats in 3 groups : K without any exposure, P1 exposed to 1 coil
repellent 8 hours/day, and P2 exposed to 5ml spray mosquito repellent 8
hours/day. TBARS test is used as Malondialdehyde level measurement method.
Result data of this research is analyzed by One Way ANOVA test and Post Hoc
test
Results: K group mean malondialdehyde level is 0.087880 nmol/mg, P1 group is
0.162240 nmol/mg, and P2group is 0.120970 nmo/mg. One Way ANOVA test
result shows (p= 0.000) and Post Hoc test result shows P1 towards P2 (p=0.000).
Conclusion: There is difference in malondialdehyde level of albino rats which
exposed to coil mosquito repellent and that exposed to spray mosquito repellent
Keywords: malondialdehyde, coil repellent, spray mosquito repellent
Latar Belakang: Obat nyamuk bakar dan spray merupakan jenis yang paling
banyak digunakan untuk menghindari gigitan nyamuk. Asap obat nyamuk bakar
mengandung bahan aktif dan zat sisa pembakaran yang bersifat toksik, sementara
obat nyamuk spray tersebar dalam bentuk aerosol yang mudah diserap oleh tubuh.
Bahan aktif obat nyamuk akan menyebabkan peningkatan radikal bebas dalam
tubuh yang ditandai dengan peningkatan kadar malondialdehid. Tujuan penelitian
ini untuk mengetahui perbedaan kadar malondialdehid plasma tikus yang terpapar
obat nyamuk bakar dengan obat nyamuk spray.
Metode: Penelitian eksperimental ini dilakukan selama 30 hari dengan 30 ekor
tikus putih galur Sprague dawley dalam 3 kelompok: K tidak diberikan paparan,
P1 diberikan obat nyamuk bakar 1 kumparan 8 jam/hari dan P2 diberikan obat
nyamuk spray 5ml 8 jam/hari. Metode pengukuran kadar malondialdehid
dilakukan dengan uji TBARS. Data hasil penelitian dianalisis dengan uji One Way
ANOVA dan uji Post Hoc.
Hasil: Kadar malondialdehid rerata kelompok K adalah 0.087880 nmol/mg,
kelompok P10.162240 nmol/mg dan P2 0.120970 nmol/mg dengan hasil uji One
Way ANOVA (p= 0.000) dan uji Post Hoc P1 terhadap P2 (p=0.000).
Kesimpulan: Terdapat perbedaan kadar malondialdehid plasma tikus putih yang
terpapar obat nyamuk bakar dengan obat nyamuk spray
Kata kunci: malondialdehid, obat nyamuk bakar, obat nyamuk spray
date: 2021
date_type: published
publisher: FAKULTAS KEDOKTERAN
place_of_pub: UNIVERSITAS LAMPUNG
citation:   Humairoh Abdul Kadir Zubaidi, 1718011096  (2021) PERBEDAAN KADAR MALONDIALDEHID (MDA) PLASMA TIKUS PUTIH (Rattus norvegicus) GALUR Sprague dawley YANG TERPAPAR OBAT NYAMUK BAKAR DENGAN OBAT NYAMUK SPRAY.  FAKULTAS KEDOKTERAN, UNIVERSITAS LAMPUNG.     
document_url: http://digilib.unila.ac.id/60417/1/ABSTRACT%20-%20Humairoh%20Zubaidi.pdf
document_url: http://digilib.unila.ac.id/60417/2/REVISI%20LENGKAP%20-%20Humairoh%20Zubaidi.pdf
document_url: http://digilib.unila.ac.id/60417/3/sskripsi%20tanpa%20pembahasan%20fixx%20-%20Humairoh%20Zubaidi.pdf