@misc{eprints60908,
           title = {EFEKTIVITAS EKSTRAK KULIT BATANG NANGKA Artocarpus
heterophyllus Lam. TERHADAP PENANGGULANGAN PENYAKIT
MOTILE AEROMONAS SEPTICEMIA PADA IKAN LELE
SANGKURIANG Clarias gariepinus (Burchell, 1822)},
          author = {1714111012 LISA SILVIANA},
         address = {UNIVERSITAS LAMPUNG},
       publisher = {FAKULTAS PERTANIAN},
            year = {2021},
             url = {http://digilib.unila.ac.id/60908/},
        abstract = {Penelitian ini bertujuan untuk mempelajari pengaruh pemberian ekstrak kulit ba-
tang nangka terhadap penanggulangan penyakit MAS (Motile Aeromonas Septice-
mia) pada ikan lele sangkuriang (Clarias gariepinus). Penelitian ini menggunakan

rancangan acak lengkap (RAL) dengan 4 perlakuan dan 3 ulangan, yaitu pemberi-
an pakan tanpa ekstrak bahan atau kontrol dan uji tantang, pemberian 200 mg/kg

pakan ekstrak kulit batang nangka (B), 300 mg/kg pakan (C), 400 mg/kg pakan
(D) dan pemeliharaan selama 14 hari. Hasil kandungan senyawa bioaktif seperti
saponin, tanin, terpenoid dan flavonoid. Uji LD50 dengan kepadatan 108 cfu/ml,
skrining aktivitas antibakteri terbaik dosis 200 mg/l sebesar 7,09 mm, uji MIC dan
MBC didapati tidak adanya pertumbuhan bakteri dan uji toksisitas sebesar 887
mg/l. Total 160 ikan ({$\pm$} 18-23cm) dengan kepadatan 15 ikan/kontainer digunakan

dalam penelitian ini. Pengambilan data dilakukan pada hari ke-0 dan 14 untuk me-
ngamati parameter tingkat kelangsungan hidup, tingkat kelulushidupan, laju per-
tumbuhan spesifik, rasio konversi pakan dan kualitas air. Gejala klinis diamati

setiap hari selama masa pemeliharaan. Data dianalisis dengan Anova pada taraf
kepercayaan 95\% dan dilanjutkan dengan uji Duncan. Hasil menunjukkan bahwa

pemberian ekstrak kulit batang nangka berpengaruh terhadap tingkat kelangsung-
an hidup. Adapun tingkat kelulushidupan, laju pertumbuhan spesifik, rasio kon-
versi pakan tidak berpengaruh nyata terhadap infeksi bakteri. Gejala klinis pada

pemberian perlakuan diperoleh perbaikan luka yang berangsur membaik. Kualitas

air masih dalam kondisi normal selama perlakuan. Hasil penelitian ini menunjuk-
kan bahwa pemberian ekstrak kulit batang nangka dengan dosis 300 mg/kg pakan

merupakan perlakuan terbaik untuk melindungi ikan lele sangkuriang dari penya-
kit bakterial Motile Aeromonas Septicemia.

Kata kunci: Clarias gariepinus, ekstrak kulit batang nangka, Motile Aeromonas
Septicemia, senyawa bioaktif, skrining aktivitas antibakteri.
This study aimed to learn the effect of jackfruit bark extract on the control of
MAS (Motile Aeromonas Septicemia) in sangkuriang catfish (Clarias gariepinus).
This study used a completely randomized design (CRD) with 4 treatments and 3
replications, namely feeding without ingredient extract or control and challenge
test, giving 200 mg/kg jackfruit bark extract feed (B), 300 mg/kg feed (C), 400
mg/kg feed (D) and maintenance for 14 days. The results contained bioactive
compounds such as saponins, tannins, terpenoids and flavonoids. The LD50 tested
with a density of 108

cfu/ml, the best antibacterial activity screening at a dose of
200 mg/l was 7,09 mm, the MIC and MBC tested found no bacterial growth and
the toxicity test was 887 mg/l. A total of 160 fish ({$\pm$} 18-23cm) with a density of
15 fish/container were used in this study. Data were collected on days-0 and 14 to
observe the parameters of survival rate, survival rate, specific growth rate, feed
conversion ratio and water quality. Clinical symptoms were observed every day

during the rearing period. Data were analyzed used Anova at 95\% confidence le-
vel and continued with Duncan's test. The results showed that the administration

of jackfruit bark extract had an effect on the survival rate. As for the survival rate,
specific growth rate, feed conversion ratio had no significant effect on bacterial
infection. Clinical symptoms in the treatment obtained wound repair gradually
improved. The water quality was still in normal condition during the treatment.
The results of this study indicated that the added of jackfruit bark extract at a dose
of 300 mg/kg of feed was the best treatment to protect sangkuriang catfish from
the Motile Aeromonas Septicemia disease.
Keywords: Clarias gariepinus, jackfruit bark extract, Motile Aeromonas
Septicemia, bioactive compounds, antibacterial activity screening}
}