%A 1717021015 Kristin Natalia Br Surbakti
%T PERKEMBANGAN FETUS MENCIT (Mus musculus L) PADA MASA
ORGANOGENESIS TERHADAP LAMANYA PAPARAN ASAP ROKOK
%X Rokok merupakan salah satu faktor lingkungan yang dapat menyebabkan cacat
lahir. Kebiasaan merokok pada wanita hamil dapat menyebabkan abortus spontan
dan kematian janin prenatal, bahkan dapat menyebabkan meromelia. Nikotin pada
rokok menimbulkan kontraksi pada pembuluh darah, akibatnya aliran darah ke
janin melalui tali pusat janin akan berkurang, sehingga mengurangi kemampuan
distribusi zat makanan yang diperlukan oleh janin. Selain itu akibat karbon
monoksida yang terkandung dalam asap rokok akan mengurangi kerja
haemoglobin yang mestinya mengikat oksigen untuk disalurkan ke seluruh tubuh,
sehingga rokok akan mengganggu distribusi zat makanan serta oksigen ke janin,
meningkatkan resiko kelahiran bayi dengan berat badan kurang dari 2500 gram.
Radikal bebas akan merusak tiga komponen molekul utama dari sel tubuh yaitu
lipid, protein dan DNA.
Smoking is one of the environmental factors that could be caused disability born.
Smoking habits in pregnant women could be caused spontaneous abortion and
prenatal fetal death, may even lead to meromelia. Influence Cigarette smoking
was a direct result of the nicotine contained in it. This nicotine causes contraction
of blood vessels, resulting in blood flow to the fetus through the fetal umbilical
cord could be decreased, thereby reducing the ability distribution of nutrients
needed by the fetus. In addition, due to carbon monoxide contained in cigarette
smoke would be reduced work hemoglobin which should bind oxygen to be
distributed throughout the body, so that smoking will interfere with the
distribution of nutrients and oxygen to the fetus, increases the risk of having a
baby weighing less than 2500 grams. Free radicals would be damaged the three
main molecular components of body cells, namely: lipids, proteins and DNA.
Damage to lipids in each oxidation and in the basic process of cellular DNA
oxidation would be disrupted the integrity of the cell, so that it wolud becaused
cell death
%C UNIVERSITAS LAMPUNG
%D 2021
%I FAKULTAS MATEMATIKA DAN ILMU PENGETAHUAN ALAM
%L eprints62402