?url_ver=Z39.88-2004&rft_id=1818011010&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Hubungan+Sensitivitas+Antibiotik+terhadap+Luaran+Pasien+Sepsis+di+Ruang+Intensive+Care+Unit+(ICU)+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+Tahun+2018-2021&rft.creator=+Jaya++Firmansyah%2C+1818011010&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Latar+Belakang%3A+Sepsis+merupakan+kondisi+disfungsi+organ+yang+mengancam+nyawa+akibat+disregulasi+respon+host+terhadap+infeksi.+Terapi+antibiotik+menjadi+tata+laksana+utama+yang+diberikan+pada+pasien+sepsis.+Tingginya+angka+resistensi+antibiotik+dimasyarakat+menjadi+permasalahan+serius+dalam+terapi+sepsis+yang+mempengaruhi+luaran+pasien.+Tujuan+penelitian+ini+untuk+mengetahui+hubungan+sensitivitas+antibiotik+terhadap+luaran+pasien+sepsis+di+ruang+intensive+care+unit++(ICU)++RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+tahun+2018-2021.%0D%0AMetode%3A+Desain+penelitian+ini+adalah+analitik+observasional+dengan+pendekatan+cross+sectional.+Teknik+pengambilan+sampel+menggunakan+teknik+total+sampling.+Analisis+data+yang+digunakan+adalah+uji+chi+square.%0D%0AHasil%3A+Karakteristik+pasien+didapatkan+hasil+pasien+laki-laki+(51%2C1%25)%2C+kelompok+usia+lansia+(43%2C2%25)%2C+sumber+infeksi+sistem+pernafasan+(28%2C4%25)%2C+pasien+dengan+komorbid+(51%2C1%25)%2C+dan+pasien+sembuh+(51%2C1%25).+Profil+antibiotik+didapatkan+hasil+antibiotik+yang+paling+banyak+digunakan+seftriakson+(36%2C4%25)%2C+frekuensi+pemberian+%E2%89%A42+kali+(65%2C9%25)%2C+lama+pemberian+%E2%89%A47+hari+(76%2C1%25)%2C+dan+antibiotik+yang+sensitif+(59%2C1%25).+Analisis+bivariat+didapatkan+hasil+terdapat+hubungan+bermakna+antara+sensitivitas+antibiotik+terhadap+luaran+pasien+sepsis+di+ruang+intensive+care+unit++(ICU)++RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+tahun+2018-2021+dengan+nilai+p%3D0%2C01.%0D%0AKesimpulan%3A+Terdapat+hubungan+sensitivitas+antibiotik+terhadap+luaran+pasien+sepsis+di+ruang+intensive+care+unit++(ICU)+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+tahun+2018-2021.%0D%0A%0D%0ABackground%3A+Sepsis+is+a+life-threatening+condition+of+organ+dysfunction+due+to+dysregulation+of+the+host+response+to+infection.+Antibiotic+therapy+is+the+main+treatment+for+sepsis+patients.+The+high+rate+of+antibiotic+resistance+in+the+community+is+a+serious+problem+in+sepsis+therapy+that+affects+patient+outcomes.+The+purpose+of+this+study+was%0D%0Ato+determine+the+correalation+between+antibiotic+sensitivity+and+the+outcome+of+sepsis+patients+in+intensive+care+unit++(ICU)+RSUD+Dr.+H.+Abdul+Moeloek+Lampung+Province+2018-2021.%0D%0AMethod%3A+The+design+of+this+research+was+observational+analytic+with+cross+sectional+approach.+Total+sampling+technique+was+used.+Analysis+of+the+data+used+is+chi+square+test.%0D%0AResults%3A+The+characteristics+of+sepsis+patients+were+male+(51.1%25)%2C+elderly+age+group+(43.2%25)%2C+respiratory+tract+infection+(28.4%25)%2C+patients+with+comorbidities+(51.1%25)%2C+and%0D%0Athe+patient+recovered+(51.1%25).+The+antibiotic+profile+showed+that+the+most+widely+used+antibiotic+was+ceftriaxone+(36.4%25)%2C+frequency+of+administration+2+times+(65.9%25)%2C+duration+of+administration+%E2%89%A47+days+(76.1%25)%2C+and+sensitive+antibiotics+(59.1%25).+Bivariate+analysis+showed+that+there+was+a+significant+correlation+between+antibiotic+sensitivity+and+outcome+of+sepsis+patients+in+the+intensive+care+unit++(ICU)+RSUD+Dr.+H.+Abdul+Moeloek+Lampung+Province+in+2018-2021+with+a+p+value+of+0.01+(%3C0.05).%0D%0AConclusion%3A+There+was+a+significant+correlation+between+antibiotic+sensitivity+and+the+outcome+of+sepsis+patients+in+intensive+care+unit++(ICU)+RSUD+Dr.+H.+Abdul+Moeloek+Lampung+Province+2018-2021.%0D%0A%0D%0A&rft.publisher=Fakultas+Kedokteran&rft.date=2022-06-16&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F63408%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F63408%2F2%2FFILE%2520SKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F63408%2F3%2FFILE%2520SKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=+++Jaya+Firmansyah%2C+1818011010++(2022)+Hubungan+Sensitivitas+Antibiotik+terhadap+Luaran+Pasien+Sepsis+di+Ruang+Intensive+Care+Unit+(ICU)+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+Tahun+2018-2021.++Fakultas+Kedokteran%2C+Universitas+Lampung.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F63408%2F