title: EFFECTIVINES WHOLE CELL VACCINE Edwardsiella ictaluri (Hawke et al., 1981) WITH DIFFERENT DOSAGES AND METHODS FOR PROTECTING SIAMESE CATFISH Pangasianodon hypophthalmus (Sauvage et al., 1878) AGAINST EDWARDSILIOSIS DISEASE creator: LISTIA, OCTA subject: 630 Pertanian dan teknologi yang berkaitan description: One of major problem of siamese catfish (Pangasianodon hypophthalmus) cul-ture is Edwardsiliosis, the bacterial disease due to Edwardsiella ictaluri infection. Edwardsiliosis bacterial disease causes economic losses because it causes high mortality and reduces the quality of fishery products. Currently, the use of anti-biotics as an effort to control the disease has been prohibited due to the impact of residual hazards, resistance and decreased food safety value. Therefore, there is needed an alternative solution that is effective, efficient and applicable through the vaccines application in fish culture. The aim of this research was to analyze the effectiveness of the whole cell Edwardsiella ictaluri vaccine with different doses and different administration methods to protect siamese catfish (Pangasia-nodon hypophthalmus) from Edwardsiellosis disease. The research was conducted using 3 methods, namely oral vaccine, immersion vaccine, and injection vaccine. Each method consisted of 4 different dose treatments with 3 replications. The results showed that the vaccine application using different methods resulted in different survival rates, relative survival rates, specific growth rates and mean time to death. The oral vaccine method using each different dose resulted in the best survival rate, relative survival percentage, and mean time to death. The immersion vaccine method with a dose of 109 CFU resulted in the highest specific growth rate siamase of catfish. Keywords: Whole cell vaccine, Edwardsiella ictaluri, siamese catfish, Edwardsiliosis disease publisher: FAKULTAS PERTANIAN date: 2022-05-18 type: Skripsi type: NonPeerReviewed format: text identifier: http://digilib.unila.ac.id/64364/1/ABSTRAK%28ABSTRACT%29.pdf format: text identifier: http://digilib.unila.ac.id/64364/2/SKRIPSI%20FULL.pdf format: text identifier: http://digilib.unila.ac.id/64364/3/SKRIPSI%20TANPA%20BAB%20PEMBAHASAN.pdf identifier: LISTIA, OCTA (2022) EFFECTIVINES WHOLE CELL VACCINE Edwardsiella ictaluri (Hawke et al., 1981) WITH DIFFERENT DOSAGES AND METHODS FOR PROTECTING SIAMESE CATFISH Pangasianodon hypophthalmus (Sauvage et al., 1878) AGAINST EDWARDSILIOSIS DISEASE. FAKULTAS PERTANIAN, UNIVERSITAS LAMPUNG. relation: http://digilib.unila.ac.id/64364/