?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PENGARUH+PEMBERIAN+EKSTRAK+BAWANG+PUTIH+(ALLIUM+%0D%0ASATIVUM)+TERHADAP+PENURUNAN+KADAR+TRIGLISERIDA+PADA+%0D%0ATIKUS+PUTIH+JANTAN+(RATTUS+NOVERGICUS)+GALUR+SPRAGUE+%0D%0ADAWLEY+YANG+DIBERIKAN+DIET+TINGGI+LEMAK&rft.creator=Tryvanie+Rakhmadianysah%2C+1118011136&rft.subject=+&rft.description=PENGARUH+PEMBERIAN+EKSTRAK+BAWANG+PUTIH+(ALLIUM+%0D%0ASATIVUM)+TERHADAP+PENURUNAN+KADAR+TRIGLISERIDA+PADA+%0D%0ATIKUS+PUTIH+JANTAN+(RATTUS+NOVERGICUS)+GALUR+SPRAGUE+%0D%0ADAWLEYYANG+DIBERIKAN+DIET+TINGGI+LEMAK%0D%0AOleh%0D%0ATryvanie+R+Putra%0D%0AABSTRAK%0D%0ALatar+belakang%3A+Dislipidemia+merupakan+faktor+resiko+terjadinya+aterosklerosis.+%0D%0ABawang+putih+memiliki+efek+menguntungkan+pada+faktor+resiko+kardiovaskular+%0D%0Aseperti+dislipidemia%2C+hipertensi%2C+dan+hiperglikemia.+Penelitian+ini+bertujuan+untuk+%0D%0Amengetahui+fungsi+pemberian+ekstrak+bawang+putih+dalam+menurunkan+kadar+%0D%0Akolesterol+trigliserida+pada+tikus+yang+diberikan+pakan+tinggi+lemak%0D%0AMetode%3A+Penelitian+ini+dilakukan+selama+28+hari+menggunakan+25+tikus+putih+(Rattus+%0D%0Anovergicus)+jantan+galur+Sprague+Dawley+yang+dibagi+menjadi+5+kelompok+dengan+5+%0D%0Aekor+tikus+tiap+kelompok.+Kelompok+kontrol+negatif+(N)+diberikan+pakan+standar.+%0D%0AKelompok+kontrol+positif+(KT)+diberikan+diet+tinggi+lemak+intermitten.+Kelompok+P1%2C+%0D%0AP2+dan+P3+diberikan+diet+tinggi+lemak+intermitten+ditambah+ekstrak+bawang+putih+0.5+%0D%0Aml%2C+0.025+ml%2C+dan+0.1+ml.%0D%0AHasil%3A+Uji+Kruskal-Wallis+menunjukkan+p%3E0%2C05+(p%3D0%2C075)+menunjukan+hasil+yang+%0D%0Atidak+bermakna.%0D%0AKesimpulan%3A+Pemberian+ekstrak+bawang+putih+secara+statistik+tidak+menunjukkan+%0D%0Ahasil+yang+signifikan+terhadap+penurunan+kadar+trigliserida.%0D%0AKata+Kunci%3A+Dislipidemia%2C+bawang+putih%2C+trigliserida%0D%0A%0D%0A%0D%0ATHE+EFFECTS+OF+GARLIC+EXTRACT+(ALLIUM+SATIVUM)+IN+%0D%0ADECREASING+TRIGLYCERIDE+RATE+IN+MALE+WHITE+MICE+(RATTUS+%0D%0ANORVEGICUS)+OF+THE+SPRAGUE+DAWLEYSTRAIN+ON+HIGH+FAT+DIET%0D%0ABy+%0D%0ATryvanie+R+Putra%0D%0AAbstract%0D%0ABackground+%3A+Dyslipidemia+is+one+of+the+risk+factors+of+atherosclerosis+incidence.+In+%0D%0Aseveral+studies%2C+garlic+shows+many+positive+effects+on+the+risk+factors+of+%0D%0Acardiovascular+disease+such+as+dyslipidemia%2C+hypertension%2C+and+hyperglycemia.+This+%0D%0Aresearch+is+meant+to+discover+the+effects+of+garlic+extract+in+decreasing+the+triglyceride+%0D%0Arate+on+white+mice+that+is+given+high+fat+diet+for+a+certain+amount+of+time.+%0D%0AMethods+%3A+This+is+research+was+conducted+for+28+days+using+25+male+white+mice+%0D%0A(Rattus+norvegicus)+of+the+Sprague+Dawley+strain+that+was+divided+onto+5+different+%0D%0Agroups%2C+with+equally+5+mice+in+each+group.+The+negative+control+(N)+group+was+given+%0D%0Astandard+diet.+While+the+positive+control+(KT)+was+given+high+fat+diet+intermittently.+%0D%0AAs+for+the+rest+of+the+groups%2C+which+are+P1%2C+P2%2C+and+P3%2C+are+given+high+fat+diet+also+%0D%0Aintermittently%2C+and+also+exposed+to+garlic+extract+in+the+concentration+of+0.5+ml%2C+0.025+%0D%0Aml%2C+and+0.1+ml.%0D%0AResult+%3A+Kruskal-Wallis+test+showed+the+result+as+p%3E0.05+(p%3D0.075)+means+that+the+%0D%0Aresult+of+the+conducted+research+as+of+above+was+insignificant.%0D%0AConclusion+%3A+The+exposure+of+garlic+extract+was+statistically+measured+and+proven+to+%0D%0Abe+insignificant+towards+the+decreasing+of+triglyceride+rate.%0D%0AKeywords+%3A+Dyslipidemia%2C+garlic%2C+triglyceride&rft.publisher=Fakultas+Kedokteran&rft.date=2015-01-22&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F2%2FABSTRACT.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F3%2FCOVER%2520DALAM.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F11%2FHALAMAN%2520PENGESAHAN.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F12%2FHALAMAN%2520PERSETUJUAN.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F10%2FPERNYATAAN.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F5%2FDAFTAR%2520ISI.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F4%2FDAFTAR%2520GAMBAR.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F6%2FDAFTAR%2520TABEL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F7%2FDAFTAR%2520LAMPIRAN.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F8%2FRIWAYAT%2520HIDUP.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F9%2FSANWACANA.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F13%2FBAB%25201.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F6607%2F14%2FBAB%2520II.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.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