TY  - GEN
CY  - Universitas Lampung
ID  - eprints67109
UR  - http://digilib.unila.ac.id/67109/
A1  - RR Astri Nur Azizah Utama, 1918011030
Y1  - 2022/11/23/
N2  - ABSTRACT

THE EFFECT OF GIVING METHANOL EXTRACT OF LAMPUNG 
KEPOK BANANA PEEL (Musa acuminata balbisiana colla) ON 
TOTAL CHOLESTEROL OF MALE WHITE RATS
(Rattus norvegicus) Sparague Dawley
INDUCED BY HIGH DIET FAT

By
Rr Astri Nur Azizah Utama

Background: Dyslipidemia is a lipid metabolism disorder which is a high risk 
factor for coronary heart disease. Musa acuminata balbisiana colla contains 
secondary metabolites which are thought to prevention on increasing in cholesterol.

Methods: This research is an experimental study with a post-test only control group 
design carried out for 30 days using 20 experimental animals, Rattus norvegicus 
Sparague dawley. There were 4 treatment groups, they are KN was only given 
standard feed, K+ was given quail egg yolk induction, K- was given quail egg yolk 
induction and simvastatin 10 mg/day, KP was given quail egg yolk induction, 
respectively, and peel extract of Musa paradisiaca L. Then the rats were terminated 
using ketamine-xylazine and blood drawn through the heart to be checked for 
cholesterol. 

Results: The results of the normality test of saphiro-wilk and levene homogeneity 
obtained p>0.05. In the one-way anova test, cholesterol levels was 0.007 (p<0.05), 
which indicated that there were significant differences between groups. The results 
of the post hoc LSD test on K+ cholesterol were significantly different from KP 
(p<0.05).

Conclusion: The administration of Musa acuminata balbisiana colla peel extract 
had an effect on preventing the increase in cholesterol levels in rats fed a high-fat 
diet.

Keywords: Dyslipidemia, Musa acuminata balbisiana colla, Saba Bananan
Cholesterol.

PB  - Fakultas Kedokteran
TI  - PENGARUH PEMBERIAN EKSTRAK METANOL KULIT PISANG KEPOK LAMPUNG (Musa acuminata balbisiana colla)TERHADAP KADAR KOLESTEROL TOTAL PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR Sprague dawley YANG DIINDUKSI DIET TINGGI LEMAK
AV  - restricted
ER  -