?url_ver=Z39.88-2004&rft_id=1918011079&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=EFEK+PEMBERIAN+EKSTRAK+DAUN+BAKAU+(Rhizophora+apiculata)+TERHADAP+PENYEMBUHAN+LUKA+BAKAR+TIKUS+PUTIH+JANTAN+(Rattus+novergicus)+GALUR+SPRAGUE+DAWLEY&rft.creator=INNA%2C+KURNIAJI&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Pendahuluan%3A+Luka+bakar+adalah+rusak+atau+hilangnya+jaringan+yang+disebabkan+oleh+sumber+panas+dan+dapat+dibagi+menjadi+tiga+derajat+yakni+derajat+I%2CIIA%2CIIB%2Cdan+III.+Untuk+membantu+proses+penyembuhan+luka+bakar+dapat+diberikan+agen+antiinflamasi%2C+antioksidan%2C+salah+satunya+adalah+penggunaan+daun+bakau.+Salah+satu+cara+alternatif+yang+dilakukan+dengan+membuatnya+menjadi+ekstrak+etanol+daun+bakau.+Studi+ini+bertujuan+untuk+melihat+percepatan+penyembuhan+luka+bakar+dengan+pemberian+ekstrak+daun+bakau+(Rhizopora+apiculata)%0D%0AMetode%3A+Penelitian+ini+merupakan+penelitian+true+experimental+dengan+post-test+only+control+group+design+yang+terbagi+atas+5+kelompok+%3A+K+normal+%3Atanpa+perlakuan%2C+K%2B%3Abioplacenton%2C+P1%3Aekstrak+20%25%2C+P2%3Aekstrak+30%25%2C+P3%3Aekstrak+40%25.+Luka+bakar+diamati+selama+21+hari%2C+dinilai+dengan+melihat+rata-rata+penyusutan+luka%2C+lama+penyembuhan+luka%2C+dan+skor+instrumen+Bates-Jensen.%0D%0AHasil%3A+Berdasarkan+hasil+uji+statistik+didapatkan+adanya+efek+pemberian+ekstrak+daun+bakau+(Rhizopora+apiculata)+terhadap+penyembuhan+luka+bakar+pada+tikus+putih+berupa+penyusutan+luas+luka+bakar+(P+Value%3A+0.001).+Terdapat+efek+pemberian+ekstrak+daun+bakau+(Rhizopora+apiculata)+terhadap+lama+penyembuhan+luka+bakar+pada+tikus+putih+(P+Value%3A+0.001).+Terdapat+dosis+yang+efektif+pada+ekstrak+daun+bakau+(Rhizopora+apiculata)+dengan+konsentrasi+40%25+dan+memiliki+tingkat+efektivitas+yang+lebih+baik+dalam+penyembuhan+luka+bakar+dibandingkan+dengan+obat+standar+bioplacenton.%0D%0AKesimpulan%3A+Terdapat+efek+yang+baik+pada+pemberian+ekstrak+daun+bakau+(Rhizophora+apiculata)+terhadap+penyembuhan+luka+bakar+tikus+putih+jantan+(Rattus+novergicus)+galur+Sprague+dawley+terutama+dengan+konsentrasi+eksrak+40%25%0D%0AKata+Kunci%3A+Luka+bakar%3B+ekstrak+Rhizophora+apiculata%0D%0A%0D%0ABackground%3A+Burn+wound+is+a+damage+or+loss+of+tissues+caused+by+contant+with+heat+source+and+can+be+classified+into+three+degree+there+are+I%2C+IIA%2C+IIB%2C+and+III+degree.+To+help+the+healing+process+of+burns%2C+anti-inflamatory%2C+antioxidant+agents+can+be+given%2C+such+as+the+application+of+mangroves+leaves.+One+of+the+alternative+ways+is+make+mangrove+leaf+extract.+This+study+is+aimed+to+know+the+accelerated+healing+of+burns+by+apply+mangrove+leaf+extract+(Rhizopora+apiculata)%0D%0AMethods%3A+This+study+was+a+true+experimental+study+with+post-test+only+control+group+design+that+grouped+into+five%3A+K+normal%3Awithout+treatment%2C+K%2B%3Abioplacenton%2C+P1%3A+extract+20%25%2C+P2%3A+extract+30%25%2C+P3%3A+extract+40%25.+Burn+wounds+were+observed+for+21+days%2C+assessed+with+average+wound+shortening%2C+wound+healing+time%2C+and+Bates-Jensen+wound+assament+tool.%0D%0AResult%3A+Based+on+the+results+of+statistical+tests%2C+it+was+found+that+there+was+an+effect+of+giving+mangrove+leaf+extract+(Rhizopora+apiculata)+on+the+healing+of+burns+in+white+rats+in+the+form+of+a+reduction+in+the+area+of+the+burn+(P+Value%3A+0.001).+There+is+an+effect+of+giving+mangrove+leaf+extract+(Rhizopora+apiculata)+on+the+healing+time+of+burns+in+white+rats+(P+Value%3A+0.001).+There+is+an+effective+dose+of+mangrove+leaf+extract+(Rhizopora+apiculata)+with+a+concentration+of+40%25+for+healing+burns%2C+and+has+a+better+level+of+effectiveness+in+healing+burns+compared+to+the+standard+drug+bioplacenton.%0D%0AConclusion%3A+There+is+a+good+effect+on+the+administration+of+mangrove+leaf+extract+(Rhizophora+apiculata)+on+the+healing+of+burns+of+male+white+rats+(Rattus+novergicus)+Sprague+Dawley+strain%2C+especially+with+extract+concentration+of+40%25.%0D%0AKeywords%3A+Burn+wound%2C+Rhizophora+apiculata+extract.%0D%0A%0D%0A&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2023-01-19&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F68663%2F1%2F1.%2520ABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F68663%2F2%2F2.%2520SKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F68663%2F3%2F3.%2520SKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++INNA%2C+KURNIAJI++(2023)+EFEK+PEMBERIAN+EKSTRAK+DAUN+BAKAU+(Rhizophora+apiculata)+TERHADAP+PENYEMBUHAN+LUKA+BAKAR+TIKUS+PUTIH+JANTAN+(Rattus+novergicus)+GALUR+SPRAGUE+DAWLEY.++FAKULTAS+KEDOKTERAN%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F68663%2F