TY  - GEN
CY  - UNIVERSITAS LAMPUNG
ID  - eprints68999
UR  - http://digilib.unila.ac.id/68999/
A1  - Erlita , Kusuma Wardani
Y1  - 2023/01/27/
N2  - 
 
ABSTRACT


 
ANTIBACTERIAL EFFECTIVENESS TEST OF TURMERIC RHIZOME
EXTRACT Curcuma domestica AGAINST Escherichia coli and  
Shigella dysenteriae 
 


By

 
ERLITA KUSUMA WARDANI



 
Background: Turmeric is one of the plants that is becoming a concern, especially
in tropical areas such as in Indonesia. Turmeric have many known functions, in the
health sector, turmeric also have properties in overcoming diarrhea or have an
antibacterial effect against bacteria that cause diarrhea. Turmeric rhizome
(Curcuma domestica) have antibacterial compounds, namely terpenoids, saponins,
and tannins. This study was conducted to examine the antibacterial effect of
Turmeric rhizome extract (Curcuma domestica) against Escherichia coli and
Shigella dysenteriae bacteria.
Methods: This research was conducted November 2022 at the Laboratory of
Microbiology and Parasitology, Faculty of Medicine, University of Lampung.
Turmeric rhizome extract was obtained from the Laboratory of Organic Chemistry,
University of Lampung with Maceration extraction technique. The antibacterial
activity of turmeric rhizome extract was carried out in vitro using the disc  diffusion
method on Mueller-Hinton Agar media.
Results. The results of this study showed that there was antibacterial activity of
Curcuma domestica turmeric rhizome extract against Escherichia coli and Shigella
dysenteriae bacteria with strong inhibition at concentrations of 50% and 100%, but
the antibacterial effect did not exceed the positive control.
Conclusion. There is antibacterial effectiveness of Curcuma domestica turmeric
rhizome extract against the growth inhibition of Escherichia coli and Shigella
dysenteriae. 

Keywords: Escherichia coli, turmeric rhizome, Shigella dysenteriae. 

 
ABSTRAK

 
UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK RIMPANG KUNYIT
Curcuma domestica TERHADAP BAKTERI Escherichia coli 
DAN Shigella dysenteriae

 
Oleh
 
 
ERLITA KUSUMA WARDANI



 
Latar Belakang: Kunyit merupakan salah satu tanaman obat keluarga atau TOGA
yang sedang menjadi perhatian banyak kalangan terutama di wilayah tropis seperti
di negara Indonesia. Kunyit juga telah banyak diketahui fungsinya, di bidang
kesehatan kunyit juga memiliki khasiat dalam mengatasi diare atau memiliki efek
antibakteri terhadap bakteri-bakteri yang dapat menyebabkan diare. Rimpang
kunyit (Curcuma domestica) memiliki senyawa antibakteri yaitu terpenoid,
saponin, dan tanin. Penelitian ini dilakukan untuk menguji efek antibakteri ekstrak
rimpang kunyit (Curcuma domestica) terhadap bakteri Escherichia  coli dan
Shigella dysenteriae.
Metode: Penelitian ini dilakukan pada bulan November 2022 di Laboratorium
Mikrobiologi dan Parasitologi Fakultas Kedokteran Universitas Lampung. Ekstrak
rimpang kunyit Curcuma domestica  didapatkan dari Laboratorium Kimia Organik
Universitas Lampung dengan teknik ekstraksi yaitu maserasi. Aktivitas antibakteri
ekstrak rimpang kunyit (Curcuma domestica) dilakukan secara in vitro
menggunakan metode disc diffusion pada media Mueller-Hinton Agar.
Hasil: Hasil penelitian ini menunjukan adanya aktivitas antibakteri ekstrak rimpang
kunyit Curcuma domestica terhadap bakteri Escherichia coli dan Shigella
dysenteriae dengan daya hambat kuat yaitu pada konsentrasi 50% dan 100%,
namun efek antibakteri ini tidak melebihi kontrol positif.
Simpulan : Terdapat efektivitas antibakteri ekstrak rimpang kunyit Curcuma
domestica terhadap daya hambat pertumbuhan Escherichia coli dan Shigella
dysenteriae.

Kata kunci: Rimpang kunyit, Escherichia coli, Shigella dysenteriae. 
PB  - FAKULTAS KEDOKTERAN
TI  - UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK RIMPANG KUNYITCurcuma domestica TERHADAP BAKTERI Escherichia coli 
DAN Shigella dysenteriae 
AV  - restricted
ER  -