creators_name: Siti Nur, Hasanah creators_id: 1918031026 type: other datestamp: 2023-06-07 08:35:27 lastmod: 2023-06-07 08:35:27 metadata_visibility: show title: UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN BELIMBING MANIS (Averrhoa carambola L) MENGGUNAKAN METODE ULTRASONIC ASSISTED EXTRACTION TERHADAP BAKTERI Streptococcus pyogenes SECARA IN VITRO ispublished: pub subjects: 610 full_text_status: restricted abstract: Latar Belakang : Streptococcus pyogenes menyebabkan penyakit infeksi kulit yang bersifat inasif maupun non-invasif. Tanaman belimbing manis (Averrhoa carambola L) dapat digunakan sebagai alternatif untuk mengurangi tingginya kejadian resistensi akibat antibiotik. Metode ekstraksi modern Ultrasonic Assisted Extraction memiliki banyak kelebihan dibandingkan dengan metode ekstraksi konvensional terutama dalam menghambat aktivitas pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak metanol daun belimbing manis (Averrhoa carambola L) terhadap pertumbuhan bakteri Streptococcus pyogenes. Metode : Penelitian ini adalah penelitian eksperimental untuk mengetahui efek antibakteri dari ekstrak metanol daun belimbing manis dengan metode ekstraksi sonikasi pada konsentrasi 6,25%, 12,5%, 25%, 50%, 100% (Averrhoa carambola L) terhadap bakteri Streptococcus pyogenes. Hasil : Hasil penelitian menunjukkan adanya aktivitas antibakteri ekstrak metanol daun belimbing manis (Averrhoa carambola L) dengan rerata diameter zona hambat yang didapatkan sebesar 11.48 mm, 13.00 mm, 14.66 mm and 16.10 mm yang termasuk kedalam kategori kuat. Kesimpulan : Terdapat aktivitas antibakteri pada ekstrak metanol daun belimbing (Averrhoa carambola L) terhadap pertumbuhan Streptococcus pyogenes. Kata Kunci : Antibakteri, Averrhoa carambola L, Ultrasonic Assisted Extraction, Streptococcus pyogenes Background : Streptococcus pyogenes causes skin infections that are both invasive and non-invasive. Starfruit (Averrhoa carambola L) can be used as an alternative to reduce the high incidence of antibiotic resistance. Modern Ultrasonic Assisted Extraction methods have many advantages compared to conventional extraction methods, especially in inhibiting bacterial growth activity. This study aims to determine the antibacterial activity of methanol extract of starfruit leaf (Averrhoa carambola L) on the growth of Streptococcus pyogenes. Methods : This research is an experimental study to determine the antibacterial effect of methanol extract of starfruit leaf by Ultrasonic Assisted Extraction method at concentrations of 6,25%, 12,5%, 25%, 50%, 100% (Averrhoa carambola L) against Streptococcus pyogenes. Results : The results showed that there was antibacterial activity of the methanol extract of starfruit leaves (Averrhoa carambola L) with the average diameter of the inhibition zones obtained being 11.48 mm, 13.00 mm, 14.66 mm and 16.10 mm which were included in the strong category. Conclusion : There is antibacterial activity in the methanol extract of starfruit leaf (Averrhoa carambola L) against the growth of Streptococcus pyogenes. Keyword : Antibacterial, Averrhoa carambola L, Ultrasonic Assisted Extraction, Streptococcus pyogenes date: 2023-05-26 date_type: published publisher: Kedokteran place_of_pub: Universitas Lampung id_number: 1918031026 citation: Siti Nur, Hasanah (2023) UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN BELIMBING MANIS (Averrhoa carambola L) MENGGUNAKAN METODE ULTRASONIC ASSISTED EXTRACTION TERHADAP BAKTERI Streptococcus pyogenes SECARA IN VITRO. Kedokteran, Universitas Lampung. document_url: http://digilib.unila.ac.id/71738/1/ABSTRAK.pdf document_url: http://digilib.unila.ac.id/71738/2/SKRIPSI%20FULL%20SITI%20NUR%20HASANAH.pdf document_url: http://digilib.unila.ac.id/71738/3/SKRIPSI%20TANPA%20PEMBAHASAN%20SITI%20NUR%20HASANAH.pdf