?url_ver=Z39.88-2004&rft_id=1917011002&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=KARAKTERISASI+DAN+UJI+AKTIVITAS+ANTIMIKROBA+KITOSAN+DAN%0D%0AEKSTRAK+SENYAWA+BIOAKTIF+DARI+ISOLAT+FUNGI+ENDOFIT&rft.creator=Wahidatun+%2C+Nur+Khasanah+&rft.subject=000+Ilmu+komputer%2C+informasi+dan+pekerjaan+umum&rft.subject=500+ilmu+pengetahuan+alam+dan+matematika&rft.subject=540+Kimia+dan+ilmu+yang+berhubungan&rft.description=Produksi+kitosan+dari+sumber+fungi+telah+mendapat+perhatian+yang+meningkat+dalam%0D%0Abeberapa+tahun+terakhir.+Pada+penelitian+ini+4+isolat+fungi+dikultivasi+pada+media+Malt%0D%0AExtract+dan+Potato+Dextose+Broth+(PDB)+selama+14+hari+yang+kemudian+diekstraksi%0D%0Adan+discreening.+Berdasaran+hasil+screening%2C+isolat+fungi+19A15-RF+pada+media+PDB%0D%0Adiperoleh+sebagai+isolat+unggul+penghasil+kitosan+dan+ekstrak+senyawa+bioaktif%0D%0Asebagai+agen+antimikroba.+Identifikasi+morfologi+isolat+19A15-RF+diindikasikan%0D%0Asebagai+genus+Aspergillus.+Scale+up+5+L+pada+media+PDB+menghasilkan+total%0D%0Arendemen+kitosan+sebesar+11%2C125%25.+Berdasarkan+hasil+uji+antibakteri+terhadap%0D%0AStaphylococcus+aureus+dan+Pseudomonas+aeruginosa+serta+antifungi+terhadap%0D%0AMalassezia+globosa%2C+kitosan+dan+ekstrak+isolat+19A15-RF+memiliki+potensi+sebagai%0D%0Aagen+antimikroba+pada+dosis+0%2C5+mg%2FmL.+Hasil+ini+menunjukkan+bahwa+fungi+endofit%0D%0Ayang+berasal+dari+organisme+laut+terkait+dengan+strain+19A15-RF%2C+belum+banyak%0D%0Adiketahui+sebagai+sumber+antimikroba.+Informasi+awal+ini+penting%2C+karena+dapat%0D%0Adigunakan+sebagai+dasar+untuk+pengembangan+lebih+lanjut+dalam+pencarian%0D%0Aantimikroba+yang+berasal+dari+fungi+endofit+yang+berasosiasi+dengan+organisme+laut.%0D%0AKata+Kunci+%3A+Fungi%2C+Kitosan%2C+Senyawa+Metabolit%2C+Antimikroba%2C+dan+Karakterisasi.%0D%0A%0D%0AProduction+of+chitosan+from+fungi+sources+has+received+increasing+attention+in+recent%0D%0Ayears.+In+this+study%2C+4+fungi+isolates+were+cultivated+on+Malt+extract+and+Potato%0D%0ADextose+Broth+(PDB)+media+for+14+days%2C+then+extracted+and+screened.+Based+on+the%0D%0Ascreening+results%2C+isolates+of+the+fungi+19A15-RF+on+PDB+media+were+obtained+as%0D%0Asuperior+isolates+producing+chitosan+and+extracts+of+bioactive+compounds+as%0D%0Aantimicrobial+agents.+Morphological+identification+of+isolate+19A15-RF+is+indicated%0D%0Aas+the+genus+Aspergillus.+Scale+up+5+L+on+PDB+media+resulted+in+a+total+yield+of%0D%0Achitosan+of+11.125%25.+Based+on+the+results+of+antibacterial+tests+against%0D%0AStaphylococcus+aureus+and+Pseudomonas+aeruginosa+and+antifungi+against%0D%0AMalassezia+globosa%2C+chitosan+and+isolate+extract+19A15-RF+have+potential+as%0D%0Aantimicrobial+agents+at+doses+of+0.5+mg%2FmL.+These+results+indicate+that+endophytic%0D%0Afungi+derived+from+marine+organisms+related+to+the+19A15-RF+strain+are+not+widely%0D%0Aknown+as+a+source+of+antimicrobials.+This+initial+information+is+important%2C+because+it%0D%0Acan+be+used+as+a+basis+for+further+development+in+the+search+for+antimicrobials+derived%0D%0Afrom+endophytic+fungi+associated+with+marine+organisms.%0D%0AKeywords%3A+Fungi%2C+Chitosan%2C+Metabolite+Compounds%2C+Antimicrobials%2C+and%0D%0ACharacterization.&rft.publisher=FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM&rft.date=2023-07-13&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F75253%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F75253%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F75253%2F3%2FSKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++Wahidatun+%2C+Nur+Khasanah+++(2023)+KARAKTERISASI+DAN+UJI+AKTIVITAS+ANTIMIKROBA+KITOSAN+DAN+EKSTRAK+SENYAWA+BIOAKTIF+DARI+ISOLAT+FUNGI+ENDOFIT.++FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F75253%2F