?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=ANALISIS+PENGARUH+PEMBERIAN+ASUPAN+PROBIOTIK+(Lactobacillus+casei)+TERHADAP+PERUBAHAN+BERAT+BADAN+PADA+MENCIT+(Mus+musculus)+JANTAN+DENGAN+BERAT+BADAN+BERLEBIH&rft.creator=Radin+Ghefira+Naura%2C+Syarel&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Background%3A+Obesity+is+a+serious+global+health+problem%2C+especially+in+Indonesia.+This+study+explores+the+probiotic+Lactobacillus+casei%2C+which+reduces+body+weight+and+modulates+the+microbiota+in+male+mice%2C+to+provide+a+non-pharmacological+alternative+to+overcome+obesity+in+adolescents.%0D%0AMethod%3A+This+study+is+a+form+of+experimental+research+conducted+on+male+mice+(Mus+musculus)+with+overweight+Swiss+Webster+strain+aged+3-4+months+as+many+as+40.+This+study+was+conducted+in+three+stages%3A+pre-test%2C+while-test%2C+and+post-test+control+design+which+was+carried+out+for+35+days+(7+days+of+acclimatization+and+28+days+of+intervention)+in+8+groups+of+mice+divided+according+to+body+weight+and+type+of+treatment.%0D%0AResults%3A+Based+on+the+statistical+tests+that+have+been+carried+out%2C+One+Way+Annova+obtained+significant+results+with+a+P-value+%3C0.05.+The+Post-Hoc-LSD+test+indicated+a+significant+difference+in+changes+in+body+weight+experienced+by+mice+with+overweight+compared+to+mice+with+normal+body+weight.%0D%0AConclusion%3A+Probiotics+of+the+Lactobacillus+casei+type+can+provide+anti-obesity+effects+by+modulating+the+intestinal+microbiota.%0D%0A%0D%0AKeywords%3A+non-pharmacological+alternatives%2C+microbiota%2C+obesity%2C+probiotics.%0D%0A%0D%0ALatar+Belakang%3A+Obesitas+adalah+masalah+kesehatan+global+yang+serius%2C+terutama+di+Indonesia.+Penelitian+ini+mengeksplorasi+probiotik+Lactobacillus+casei+untuk+menurunkan+berat+badan+dan+memodulasi+mikrobiota+pada+mencit+jantan%2C+dengan+tujuan+memberikan+alternatif+non-farmakologi+untuk+mengatasi+obesitas+pada+remaja.+%0D%0AMetode%3A+Penelitian+ini+adalah+bentuk+dari+penelitian+eksperimental+yang+dilakukan+terhadap+mencit+(Mus+musculus)+jantan+dengan+berat+badan+berlebih+galur+Swiss+Webster+usia+3-4+bulan+sebanyak+40+ekor.+Penelitian+ini+dilakukan+dengan+tiga+tahap%3A+pre-test%2C+while-test%2C+dan+post-test+control+design+yang+dilakukan+selama+35+hari+(7+hari+aklimatisasi+dan+28+hari+intervensi)+pada+8+kelompok+mencit+yang+dibagi+sesuai+berat+badan+dan+jenis+perlakuannya.+%0D%0AHasil%3A+Berdasarkan+hal+uji+statistik+yang+telah+dilakukan%2C+One+Way+Annova+didapatkan+hasil+yang+signifikan+dengan+P+%3C0.05.+Sementara+pada+uji+Post-Hoc-LSD+mengindikasikan+perbedaan+yang+signifikan+terhadap+perubahan+berat+badan+yang+dialami+oleh+mencit+dengan+berat+badan+berlebih+daripada+mencit+dengan+berat+badan+normal.%0D%0ASimpulan%3A+Probiotik+jenis+Lactobacillus+casei+dapat+memberikan+pengaruh+antiobesitas+dengan+modulasi+mikrobiota+usus.%0D%0A%0D%0AKata+Kunci%3A+alternatif+non-farmakologi%2C+mikrobiota%2C+obesitas%2C+probiotik.%0D%0A&rft.publisher=Kedokteran&rft.date=2024-11-20&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81211%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81211%2F2%2FFILE%2520SKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81211%2F3%2FFILE%2520SKRIPSI%2520FULL%2520TANPA%2520PEMBAHASAN.pdf&rft.identifier=++Radin+Ghefira+Naura%2C+Syarel++(2024)+ANALISIS+PENGARUH+PEMBERIAN+ASUPAN+PROBIOTIK+(Lactobacillus+casei)+TERHADAP+PERUBAHAN+BERAT+BADAN+PADA+MENCIT+(Mus+musculus)+JANTAN+DENGAN+BERAT+BADAN+BERLEBIH.++Kedokteran%2C+Universitas+Lampung.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F81211%2F