?url_ver=Z39.88-2004&rft_id=2118011062&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Hubungan+Kadar+Ureum+dan+Kreatinin+Darah+serta+GFR+dengan+Temuan+Ultrasonografi+pada+Pasien+Chronic+Kidney+Disease+di+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung&rft.creator=Fransiska%2C+Adisti&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Latar+Belakang%3A+Chronic+kidney+disease+termasuk+salah+satu+masalah+kesehatan+dunia+yang+melibatkan+sekitar+10%25+dari+populasi+dunia+sebagai+penderita.+Kerusakan+ginjal+pada+CKD+bersifat+progresif+dan+irreversible+yang+umumnya+akan+berakhir+pada+kondisi+gagal+ginjal.+Penilaian+pada+kadar+ureum+dan+kreatinin+serum+merupakan+salah+satu+cara+untuk+mendiagnosis+CKD.+Kerusakan+ginjal+terutama+pada+tahap+filtrasi+glomerulus+dapat+diketahui+dengan+pengukuran+Glomerular+Filtration+Rate+(GFR).+Salah+satu+teknik+pencitraan+yang+dapat+dilakukan+adalah+ultrasonografi+(USG).Tujuan+dari+penelitian+ini+adalah+untuk+mengetahui+hubungan+kadar+ureum+dan+kreatinin+darah+serta+GFR+dengan+temuan+ultrasonografi+pada+pasien+CKD+di+RSUD+Dr.+H.+Abdul+Moeloek.%0D%0AMetode%3A+Desain+penelitian+yang+digunakan+adalah+cross+sectional.+Data+yang+digunakan+pada+penelitian+ini+adalah+data+sekunder+berupa+data+rekam+medis+pasien+CKD+di+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung.+Hipotesis+diuji+dengan+menggunakan+analisis+korelasi+Spearman.%0D%0AHasil%3A+Hasil+penelitian+menunjukkan+bahwa+terdapat+hubungan+antara+GFR+dengan+ukuran+dan+ekogenisitas+ginjal+(p+value+0%2C000+dan+0%2C007)+dengan+kekuatan+hubungan+cukup+dan+lemah+(r%3D0%2C330%3B+r%3D0%2C227).+Serta+terdapat+hubungan+antara+kadar+kreatinin+dengan+ukuran+dan+ekogenisitas+ginjal+(p+value+0%2C000+dan+0%2C032)+dengan+kekuatan+hubungan+cukup+dan+lemah+(r%3D0%2C334%3B+r%3D0%2C181)+Analisis+ROC+menyatakan+cut+off+value+kreatinin+berada+pada+nilai+5%2C03+dan+4%2C91+sehingga+dapat+mempengaruhi+ukuran+dan+ekogenisitas+ginjal.+Tidak+terdapat+hubungan+antara+kadar+ureum+darah+dengan+ukuran+dan+ekogenisitas+ginjal.%0D%0AKesimpulan%3A+Terdapat+hubungan+antara+kadar+kreatinin+dan+GFR+dengan+ukuran+dan+ekogenisitas+ginjal+pada+pasien+CKD.%0D%0A%0D%0ABackground%3A+Chronic+kidney+disease+(CKD)+affects+approximately+10%25+of+the+global+population+and+is+characterized+by+progressive%2C+irreversible+kidney+damage+that+often+leads+to+kidney+failure.+Serum+urea+and+creatinine+levels+along+with+the+Glomerular+Filtration+Rate+(GFR)+are+key+diagnostic+markers.+Ultrasonography+(USG)+is+a+non-invasive+imaging+modality+used+to+assess+structural+kidney+changes+in+CKD.+This+study+aims+to+evaluate+the+correlation+between+serum+urea%2C+creatinine+levels%2C+GFR%2C+and+USG+findings+in+CKD+patients+at+Dr.+H.+Abdul+Moeloek+General+Hospital.%0D%0AMethod%3A+A+cross-sectional+study+was+conducted+using+secondary+data+from+the+medical+records+of+CKD+patients+at+Dr.+H.+Abdul+Moeloek+General+Hospital%2C+Lampung+Province.+Spearman+correlation+analysis+was+used+to+assess+the+correlation.%0D%0AResults%3A+The+study+findings+demonstrate+a+significant+correlation+between+GFR+and+kidney+size+as+well+as+echogenicity%2C+with+p-values+of+0.000+and+0.007%2C+respectively%2C+indicating+moderate+(r%3D0.330)+and+weak+(r%3D0.227)+correlation+strengths.+Similarly%2C+a+significant+correlation+was+observed+between+creatinine+levels+and+kidney+size+and+echogenicity%2C+with+p-values+of+0.000+and+0.032%2C+and+correlation+strengths+categorized+as+moderate+(r%3D0.334)+and+weak+(r%3D0.181).+ROC+analysis+identified+creatinine+cutoff+values+of+5.03+and+4.91%2C+which+appear+to+influence+kidney+size+and+echogenicity.+In+contrast%2C+no+significant+correlation+was+found+between+blood+urea+levels+and+kidney+size+or+echogenicity.%0D%0AConclusion%3A+Serum+creatinine+and+GFR+are+correlated+with+size+and+echogenicity+of+kidney+USG.+Blood+urea+levels+are+not+significantly+correlated+with+kidney+size+and+echogenicity+in+USG.&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2025-01-07&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81231%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81231%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81231%2F3%2FSKRIPSI%2520FULL%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++Fransiska%2C+Adisti++(2025)+Hubungan+Kadar+Ureum+dan+Kreatinin+Darah+serta+GFR+dengan+Temuan+Ultrasonografi+pada+Pasien+Chronic+Kidney+Disease+di+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung.++FAKULTAS+KEDOKTERAN%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F81231%2F