?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=HUBUNGAN+KELAHIRAN+PREMATUR+DENGAN+KEJADIAN+SEPSIS+NEONATORUM+TERHADAP+RESISTENSI+ANTIBIOTIK+DI+NICU+RSUD+DR.+H.+ABDUL+MOELOEK+PROVINSI+LAMPUNG+PERIODE+JANUARI-+DESEMBER+2023&rft.creator=Putu%2C+Karis+Ayu+Kirana&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Latar+Belakang%3A+Bayi+lahir+prematur+adalah+salah+satu+faktor+risiko+terjadinya+sepsis+neonatorum+yang+merupakan+keadaan+darurat+karena+keterlambatan+dalam+pengobatannya+dapat+menyebabkan+kematian%2C+sedangkan+sulit+untuk+menegakkan+diagnosis+karena+gambaran+klinisnya+tidak+spesifik+dibandingkan+sepsis+pada+orang+dewasa.+Pemberian+antibiotik+empirik+yang+memadai+dan+diberikan+segera+setelah+didiagnosis%2C+sangat+penting+dalam+penatalaksanaan+namun+penggunaan+antibiotik+pada+neonatus+yang+berlebihan+dapat+memberikan+dampak+buruk+salah+satunya+menimbulkan+resistensi+terhadap+obat.+Penelitian+ini+bertujuan+untuk+mengetahui+hubungan+kelahiran+prematur+dengan+kejadian+sepsis+neonatorum+terhadap+resistensi+antibiotik+di+NICU+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+periode+Januari-Desember+2023.+Metode%3A+Penelitian+ini+merupakan+penelitian+kuantitatif+observasional+analitik+dengan+pendekatan+cross+sectional.+Data+diambil+dengan+teknik+total+sampling.+Data+yang+digunakan+adalah+data+sekunder+sejumlah+298+rekam+medis+yang+memenuhi+kriteria+inklusi+dan+eklusi.+Penelitian+ini+menggunakan+uji+analisis+Chisquare.%0D%0A%0D%0AData+rekam+medis+diambil+di+instalasi+rekam+medis+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+sepanjang+tahun+2023.+Hasil%3A+Hasil+statistik+penelitian+ini+didapatkan+hubungan+signifikan+antara+kelahiran+prematur+yang+disertai+sepsis+neonatorum+terhadap+10+antibiotik+paling+resisten+(p%3C0%2C05)%2C+dimana+bayi+lahir+prematur+dengan+sepsis+neonatorum+memiliki+risiko+lebih+tinggi+untuk+mengalami+resistensi+antibiotik.+Simpulan%3A+Terdapat+hubungan+yang+signifkan+antara+kelahiran+prematur+dengan+kejadian+sepsis+neonatorum+terhadap+resistensi+antibiotik+di+NICU+RSUD+Dr.+H.+Abdul+Moeloek+Provinsi+Lampung+periode+Januari-Desember+2023.++%0D%0AKata+kunci%3A+Sepsis+neonatorum%2C+resistensi+antibiotik%2C+kelahiran+prematur%2C+cross+sectional+study+%0D%0A%0D%0A+%0D%0ABackground%3A+Preterm+born+babies+are+one+of+the+risk+factors+for+neonatal+sepsis+which+is+an+emergency+because+delay+in+treatment+can+cause+death%2C+while+it+is+difficult+to+make+a+diagnosis+because+the+clinical+picture+is+not+specific+compared+to+sepsis+in+adults.+The+provision+of+adequate+empirical+antibiotics+and+given+immediately+after+diagnosis%2C+is+very+important+in+management+but+excessive+use+of+antibiotics+in+neonates+can+have+a+negative+impact%2C+one+of+which+causes+resistance+to+drugs.+This+study+aims+to+determine+the+relationship+between+premature+birth+and+the+incidence+of+neonatal+sepsis+and+antibiotic+resistance+in+the+NICU+of+Dr.+H.+Abdul+Moeloek+Hospital%2C+Lampung+Province%2C+from+January+to+December+2023.+%0D%0AMethods%3A+This+study+is+an+analytic+observational+quantitative+study+with+a+cross+sectional+approach.+Data+were+taken+with+total+sampling+technique.+The+data+used+was+secondary+data+of+298+medical+records+that+met+the+inclusion+and+exclusion+criteria.+This+study+used+the+Chi-square+analysis+test.+Medical+record+data+was+taken+at+the+medical+record+installation+of+Dr.+H.+Abdul+Moeloek+Hospital%2C+Lampung+Province+throughout+2023.+Results%3A+The+statistical+results+of+this+study+showed+a+significant+relationship+between+preterm+birth+accompanied+by+neonatal+sepsis+and+the+10+most+resistant+antibiotics+(p%3C0.05)%2C+where+babies+born+prematurely+with+neonatal+sepsis+have+a+higher+risk+of+developing+antibiotic+resistance.+Conclusion%3A+There+is+a+significant+relationship+between+preterm+birth+and+the+incidence+of+neonatal+sepsis+against+antibiotic+resistance+in+the+NICU+of+RSUD+Dr.+H.+Abdul+Moeloek+Lampung+Province+for+the+period+January-December+2023.++%0D%0AKeywords%3A+Neonatal+sepsis%2C+antibiotic+resistance%2C+preterm+birth%2C+cross+sectional+study+%0D%0A+&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2024-12-23&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81292%2F1%2F1.%2520ABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81292%2F2%2F2.%2520SKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81292%2F3%2F3.%2520SKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++Putu%2C+Karis+Ayu+Kirana++(2024)+HUBUNGAN+KELAHIRAN+PREMATUR+DENGAN+KEJADIAN+SEPSIS+NEONATORUM+TERHADAP+RESISTENSI+ANTIBIOTIK+DI+NICU+RSUD+DR.+H.+ABDUL+MOELOEK+PROVINSI+LAMPUNG+PERIODE+JANUARI-+DESEMBER+2023.++FAKULTAS+KEDOKTERAN%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F81292%2F