?url_ver=Z39.88-2004&rft_id=2158011005&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PENGARUH+PEMBERIAN+EKSTRAK+LADA+HITAM+(Piper+nigrum+L)+%0D%0ATERHADAP+LIBIDO+(PERILAKU+SEKSUAL)+MODEL+TIKUS+PUTIH+%0D%0AJANTAN+(RATTUS+NORVEGICUS)+DIABETES+MELITUS%0D%0A%5BTHE+EFFECT+OF+BLACK+PEPPER+(Piper+nigrum+L)+EXTRACT+ON%0D%0AMALE+WHITE+RAT+(RATTUS+NORVEGICUS)+LIBIDO+(SEXUAL%0D%0ABEHAVIOR)+WITH+DIABETES+MELLITUS%5D&rft.creator=GUSTI+AYU+MADE+PRATHITA%2C+ISVARI&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Latar+Belakang%3A+Diabetes+Melitus+mengakibatkan+komplikasi+berupa+gangguan+%0D%0Alibido+seksual.+Tanaman+herbal+Indonesia+yaitu+lada+hitam+memiliki+kandungan+%0D%0Autama+piperin+yang+berfungsi+meningkatkan+libido+seksual.+Penelitian+ini+%0D%0Abertujuan+untuk+mengetahui+pengaruh+pemberian+ekstrak+lada+hitam+(Piper+%0D%0Anigrum+L.)+pada+libido+(perilaku+seksual)+model+tikus+putih+jantan+(Rattus+%0D%0Anorvegicus)+Diabetes+Melitus.%0D%0AMetode%3A+Penelitian+eksperimental+laboratorium+dengan+desain+pos-+test+only+%0D%0Acontrol+group+design+dengan+sampel+30+tikus+putih+jantan+(Rattus+norvegicus)+%0D%0Aterdiri+atas+5+kelompok.+Masing-masing+terbagi+menjadi+kelompok+kontrol+1+(K1)+%0D%0Atikus+normal%3B+kelompok+kontrol+2+(K2)%2C+tikus+diabetes+yang+diinduksi+aloksan+150+%0D%0Amg%2Fkg%3B+kelompok+perlakuan+1+(P1)%2C+tikus+diabetes+yang+diinduksi+aloksan+150+%0D%0Amg%2Fkg+dan+diberikan+esktrak+lada+hitam+122%2C5+mg%2Fkg%3B+kelompok+perlakuan+2+(P2)%2C%0D%0Atikus+diabetes+yang+diinduksi+aloksan+150mg%2Fkg+dan+diberikan+esktrak+lada+hitam+%0D%0A245+mg%2Fkg%3B+kelompok+perlakuan+3+(P3)%2C+tikus+diabetes+yang+diinduksi+aloksan+%0D%0A150mg%2Fkg+dan+diberikan+sildenafil+1mg%2Fkg.+Penilaian+libido+dilakukan+dengan+%0D%0Apengamatan+latensi+percumbuan+dalam+detik%2C+latensi+penunggangan+dalam+detik%2C+%0D%0Adan+frekuensi+penunggangan+dalam+jumlah.%0D%0AHasil%3A+Data+latensi+percumbuan+dianalisis+dengan+Kruskal-Wallis%2C+sedangkan+data+%0D%0Alatensi+penunggangan+dan+frekuensi+penunggangan+dengan+One+Way+ANOVA.+%0D%0ALatensi+percumbuan+kelompok+P1+dan+P2+berbeda+nyata+dibanding+K2+(p%3D0%2C003%2C+%0D%0Ap%3D0%2C003)%2C+Latensi+penunggangan+kelompok+P1+berbeda+nyata+dibanding+K2+%0D%0A(p%3D0%2C000)+dan+Frekuensi+penunggangan+kelompok+P1+dan+P2+berbeda+nyata+%0D%0Adibanding+K2+(p%3D0%2C000%2Cp%3D0%2C006).%0D%0ASimpulan%3A+Ekstrak+lada+hitam+(Piper+nigrum+L.)+dapat+meningkatkan+libido+tikus+%0D%0Aputih+jantan+(Rattus+norvegicus)+Diabetes+Melitus.%0D%0A%0D%0AKata+Kunci%3A+Diabetes+Melitus%2C+Libido%2C+Lada+Hitam%2C+Piper+nigrum+Linn%2C+Tikus+Putih+Jantan+(Rattus+norvegicus).%0D%0A%0D%0A%0D%0ATHE+EFFECT+OF+BLACK+PEPPER+(Piper+nigrum+L)+EXTRACT+ON%0D%0AMALE+WHITE+RAT+(RATTUS+NORVEGICUS)+LIBIDO+(SEXUAL%0D%0ABEHAVIOR)+WITH+DIABETES+MELLITUS%0D%0A%0D%0ABackground%3A+Diabetes+Mellitus+causes+complications+in+the+form+of+sexual+libido%0D%0Adisorders.+The+Indonesian+herbal+plant%2C+namely+black+pepper%2C+contains+piperine%0D%0Awhich+functions+to+increase+sexual+libido.+This+study+aimed+to+determine+the+effect%0D%0Aof+black+pepper+(piper+nigrum+l)+extract+on+male+white+rat+(Rattus+norvegicus)%0D%0Alibido+(sexual+behavior)+with+diabetes+mellitus.%0D%0AMethods%3A+The+study+was+an+experimental+laboratory+with+a+post-test+only+control%0D%0Agroup+design+using+30+samples+of+male+white+rats+(Rattus+norvegicus)+which%0D%0Adivided+into+5+groups.+Each+divided+into%2C+control+group+1+(K1)+consist+of+normal%0D%0Arats%3B+control+group+2+(K2)%2C+diabetic+rats+induced+by+alloxan+150+mg%2Fkg%3B+treatment%0D%0Agroup+1+(P1)%2C+diabetic+rats+induced+by+alloxan+150+mg%2Fkg+and+given+black+pepper%0D%0Aextract+122.5+mg%2Fkg%3B+treatment+group+2+(P2)%2C+diabetic+rats+induced+by+alloxan+150%0D%0Amg%2Fkg+and+given+black+pepper+extract+245+mg%2Fkg%3B+treatment+group+3+(P3)%2C+diabetic%0D%0Arats+induced+by+alloxan+150mg%2Fkg+and+given+sildenafil+1mg%2Fkg.+Libido%E2%80%99s%0D%0Ameasurement+was+done+by+observing+introducing+latency+in+second%2C+mount+latency%0D%0Ain+second%2C+mount+frequency+by+its+quantity.%0D%0AResult%3A+Introducing+latency+data+was+analyzed+with+Kruskal-Wallis%2C+whereas%0D%0Amounting+latency+and+mounting+frequency+data+was+analyzed+with+One+Way%0D%0AANOVA.+The+results+show+that+introducing+latency+of+group+P1+and+P2+differ%0D%0Asignificantly+compared+to+group+K2+(p%3D0%2C003%2C+p%3D0%2C003)%2C+Mounting+latency+of%0D%0Agroup+P1+differ+significantly+compared+to+group+K2+(p%3D0%2C000)+and+mounting%0D%0Afrequency+of+group+P1+and+P2+differ+significantly+compared+to+group+K2%0D%0A(p%3D0%2C000%2C+p%3D0%2C006).%0D%0AConclusion%3A+Black+pepper+extract+enhances+male+white+rat+(Rattus+norvegicus)%0D%0Alibido+with+diabetes+mellitus.%0D%0AKeywords%3A+Diabetes+Mellitus%2C+Libido%2C+Black+Papper%2C+Piper+nigrum+Linn%2C+male%0D%0Awhite+rat+(Rattus+norvegicus).%0D%0A&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2024-12-04&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2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