?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=ANALISIS+KORELASI+KADAR+HEMOGLOBIN+A2+DENGAN+INDEKS%0D%0AERITROSIT+PADA+PASIEN+BETA-THALASSEMIA+DI+RSUD+DR.+H.%0D%0AABDUL+MOELOEK+PROVINSI+LAMPUNG+TAHUN+2023%0D%0A&rft.creator=FATHAN+%2C++QORIBA+&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=Introduction%3A+Thalassemia+is+a+genetic+disorder+that+disrupts+hemoglobin%0D%0Aproduction.+Hemoglobin+undergoes+destruction+due+to+abnormalities+in+the%0D%0Asynthesis+of+hemoglobin+or+globin+chains.+This+study+aims+to+explore+the%0D%0Acorrelation+between+hemoglobin+A2+(HbA2)+levels+and+erythrocyte+indices+in%0D%0Athalassemia+patients+at+Dr.+H.+Abdul+Moeloek+Regional+General+Hospital%2C%0D%0ALampung+Province%2C+in+2023.%0D%0AMethods%3A+This+research+employed+an+analytical+observational+study+with+a+crosssectional%0D%0Aapproach%0D%0Ausing%0D%0Aa%0D%0Atotal%0D%0Asampling%0D%0Atechnique.%0D%0AThe%0D%0Asample%0D%0Aconsisted%0D%0Aof%0D%0A39%0D%0A%0D%0Abeta-thalassemia%0D%0Apatients%0D%0Awho%0D%0Amet%0D%0Athe%0D%0Ainclusion%0D%0Aand%0D%0Aexclusion%0D%0Acriteria.%0D%0AThe%0D%0Astudy%0D%0A%0D%0Awas%0D%0A%0D%0Aconducted+from+September+to+November+2024+in+the+Medical+Records%0D%0ADepartment+of+Dr.+H.+Abdul+Moeloek+Regional+General+Hospital%2C+Lampung%0D%0AProvince.+Data+were+analyzed+using+univariate+and+bivariate+methods%2C+with%0D%0ASpearman's+correlation+test+used+to+determine+the+relationship+between+HbA2%0D%0Alevels+and+each+erythrocyte+index.%0D%0AResults%3A++The+majority+of+subjects+showed+elevated+HbA2+levels+(66.7%25)+and%0D%0Adecreased+MCV+(97.4%25)+and+MCH+(92.3%25)+levels.+A+significant+correlation+was%0D%0Afound+between+HbA2+levels+and+MCV+(p+%3D+0.001%3B+r+%3D+-0.525)+as+well+as+between%0D%0AHbA2+levels+and+MCH+(p+%3D+0.001%3B+r+%3D+-0.508).%0D%0AConclusion%3A+This+study+demonstrates+that+elevated+HbA2+levels+correlate+with%0D%0Adecreased+MCV+and+MCH+values+in+beta-thalassemia+patients%2C+while+no%0D%0Asignificant+correlation+was+observed+with+MCHC.%0D%0A%0D%0AKeywords%3A+Erythrocyte+index%2C+HbA%2C+thalassemia.%0D%0A&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2024-12-09&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81327%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81327%2F2%2FSKRIPSI%2520FULL%2520TANPA%2520LAMPIRAN.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F81327%2F3%2FSKRIPSI%2520FULL%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++FATHAN+%2C+QORIBA+++(2024)+ANALISIS+KORELASI+KADAR+HEMOGLOBIN+A2+DENGAN+INDEKS+ERITROSIT+PADA+PASIEN+BETA-THALASSEMIA+DI+RSUD+DR.+H.+ABDUL+MOELOEK+PROVINSI+LAMPUNG+TAHUN+2023.++FAKULTAS+KEDOKTERAN%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F81327%2F