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<http://digilib.unila.ac.id/id/eprint/81405> <http://purl.org/dc/terms/title> "EFEKTIVITAS EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) TERHADAP DAYA HAMBAT PERTUMBUHAN BAKTERI Propionibacterium acnes"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/81405> <http://purl.org/ontology/bibo/abstract> "ntroduction: Propionibacterium acnes is a bacteria that involved in pathogenesis\r\nof Acne vulgaris. An alternative antibiotics from natural sources is needed, one of\r\nwhich is the moringa plant. Moringa leaf extract contains active compounds such\r\nas flavonoids, tannins, alkaloids, saponins, terpenoids, and phenols as antibacterial\r\nagents.\r\nMethods: A laboratory experimental design was used. Moringa leaves were\r\nseparated from the stems and extracted using maceration method with 96% ethanol\r\nand divided into three concentration levels (2.5%, 5%, and 10%).Clindamycin\r\nphosphate 1.2% topical solution used as the positive control. Antibacterial activity\r\nwas tested using disc diffusion method on BAP inoculated with Propionibacterium\r\nacnes.Data were analyzed using non-parametric Kruskal-Wallis test, followed by\r\nPost Hoc LSD analysis to determine which treatment groups showed significant\r\ndifferences after an overall significant difference was found.\r\nResults: Bivariate analysis using Kruskal-Wallis method showed significant\r\ndifferences among all treatment groups. Post Hoc LSD analysis revealed significant\r\ndifferences between the positive control group and the 96% ethanol moringa leaf\r\nextract groups at concentrations of 2.5%, 5%, and 10% in inhibiting the growth\r\nof Propionibacterium acnes, with a p-value of 0.001 (p < 0.05) and an average\r\ninhibition zone of 0.00 mm.\r\nConclusion: There is a significant difference between the positive control group\r\nand the treatment groups with 96% ethanol moringa leaf extract at concentrations\r\nof 2.5%, 5%, and 10% against Propionibacterium acnes.\r\nKeywords: Moringa plant, Propionibacterium acnes\r\n\r\n\r\n\r\nPendahuluan: Propionibacterium acnes adalah bakteri yang berperan dalam\r\npatogenesis Acne vulgaris.Diperlukan alternatif antibiotik dari bahan alam yang\r\nbermanfaat sebagai pengganti antibiotik resisten, salah satunya tanaman\r\nkelor.Ekstrak daun kelor mengandung senyawa aktif yaitu flavonoid, tannin,\r\nalkaloid, sponin, terpenoid dan fenol sebagai antibakteri.\r\nMetode: Desian eksperimental laboratorik.Daun kelor dipisah dari tangkai dan\r\ndiekstraksi dengan metode maserasi etanol 96%, bagi menjadi 3 tingkatan\r\nkonsentrasi (2,5%, 5%, dan 10%), klindamisin fosfat 1,2% Topical Solution sebagai\r\nkontrol positif.Uji aktivitas antibakteri dengan metode disk cakram pada media\r\nBAP yang diinokulasikan bakteri Propionibacterium acnes.Data dianalisis dengan\r\nuji non-parametrik Kruskal-Wallis dilanjut uji Post Hoc LSD untuk melihat\r\nkelompok perlakuan mana yang berbeda setelah ditemukan perbedaan signifikan\r\nsecara keseluruhan.\r\nHasil: Hasil analisis bivariat metode Kruskal-Wallis menunjukkan perbedaan\r\nsignifikan antar setiap kelompok perlakuan.Uji Post Hoc LSD menunjukkan\r\nperbedaan signifikan pada kelompok kontrol positif dengan ekstrak etanol 96%\r\ndaun kelor konsentrasi 2,5%, 5%, dan 10% pada pertumbuhan bakteri\r\nPropionibacterium acnes dengan p-value sebesar 0,001 (p < 0,05) dengan rerata\r\nzona hambat 0,00 mm.\r\nKesimpulan: Terdapat perbedaan signifikan antara kelompok perlakuan kontrol\r\npositif dengan kelompok perlakuan ekstrak etanol 96% daun kelor dengan\r\nkonsentrasi 2,5%, 5%, dan 10% terhadap baketeri Propionibacterium acnes\r\nKata Kunci: Tanaman Kelor, Propionibacterium acnes"^^<http://www.w3.org/2001/XMLSchema#string> .
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<http://digilib.unila.ac.id/id/eprint/81405> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2283507> .
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<http://digilib.unila.ac.id/id/document/2283507> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2283497> .
<http://digilib.unila.ac.id/id/document/2283507> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2283497> .
<http://digilib.unila.ac.id/id/document/2283507> <http://eprints.org/relation/ispreviewThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2283497> .
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<http://digilib.unila.ac.id/id/document/2283508> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2283497> .
<http://digilib.unila.ac.id/id/document/2283508> <http://eprints.org/relation/ismediumThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2283497> .
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<http://digilib.unila.ac.id/id/document/2283509> <http://eprints.org/relation/issmallThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2283497> .
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