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<http://digilib.unila.ac.id/id/eprint/81528> <http://purl.org/dc/terms/title> "COMPARISON OF INHIBITORY EFFECTS OF PROBIOTIC\r\nSTREPTOCOCCUS THERMOPHILUS, CLINDAMYCIN, AND\r\nERYTHROMYCIN ON THE GROWTH OF CUTIBACTERIUM ACNES\r\n\r\nBACTERIA: IN VITRO STUDY"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/81528> <http://purl.org/ontology/bibo/abstract> "Background: Acne vulgaris is an inflammatory condition in the skin mostly\r\nfound in adolescents to adults. One factor that causes this condition is the\r\ndisproportion of normal flora in the skin due to colonization by Cutibacterium\r\nacnes. This study aims to evaluate the comparison of in vitro inhibitory effects of\r\nprobiotic Streptococcus thermophilus, clindamycin, and erythromycin on the\r\ngrowth of Cutibacterium acnes.\r\nMethods: This study is a laboratory experimental study to compare the inhibition\r\nzones produced by probiotic Streptococcus thermophilus, clindamycin, and\r\nerythromycin using well diffusion method.\r\nResults: There was a significant difference in the mean diameters of inhibition\r\nzone of probiotic Streptococcus thermophilus, clindamycin, and erythromycin\r\n(p=0). Erythromycin produced the largest inhibition zone against Cutibacterium\r\nacnes with an average diameter of 31,72±2,68 mm. Furthermore, clindamycin\r\nproduced the second largest inhibition zone after erythromycin with an average\r\ndiameter of 30,22±1,90 mm. The smallest inhibition zone was produced by\r\nprobiotic Streptococcus thermophilus with an average diameter of 15.56±0.58 mm.\r\nConclusion: Erythromycin produced the largest inhibition zone against in vitro\r\ngrowth of Cutibacterium acnes compared to the inhibition zones produced by\r\nclindamycin and probiotic Streptococcus thermophilus.\r\nKeywords: Cutibacterium acnes, inhibition zone, probiotic, Streptococcus\r\nthermophilus\r\n\r\nABSTRAK\r\n\r\nPERBANDINGAN DAYA HAMBAT PROBIOTIK STREPTOCOCCUS\r\nTHERMOPHILUS, KLINDAMISIN, DAN ERITROMISIN TERHADAP\r\nPERTUMBUHAN BAKTERI CUTIBACTERIUM ACNES: STUDI IN\r\n\r\nVITRO\r\n\r\nOleh\r\n\r\nFARHRY ALVINI RAHMANIA\r\n\r\nLatar Belakang: Akne vulgaris merupakan suatu kondisi inflamasi pada kulit\r\nyang banyak ditemukan pada remaja hingga dewasa. Salah satu faktor penyebab\r\nterjadinya kondisi ini ialah ketidakseimbangan flora normal pada kulit akibat\r\nkolonisasi oleh Cutibacterium acnes. Penelitian ini bertujuan untuk melihat\r\nperbandingan daya hambat probiotik Streptococcus thermophilus, klindamisin,\r\ndan eritromisin terhadap pertumbuhan Cutibacterium acnes secara in vitro.\r\nMetode: Penelitian ini merupakan penelitian eksperimental laboratorium untuk\r\nmembandingkan zona hambat probiotik Streptococcus thermophilus, klindamisin,\r\ndan eritromisin menggunakan metode difusi sumuran.\r\nHasil: Hasil penelitian ini menunjukkan ada perbedaan pada rerata zona hambat\r\nprobiotik Streptococcus thermophilus, klindamisin, dan eritromisin (p=0).\r\nEritromisin menghasilkan zona hambat terbesar terhadap Cutibacterium acnes\r\ndengan rerata diameter sebesar 31,72±2,68 mm. Selanjutnya, klindamisin\r\nmenghasilkan zona hambat terbesar kedua setelah eritromisin dengan rerata\r\ndiameter sebesar 30,22±1,90 mm. Zona hambat terkecil dihasilkan oleh probiotik\r\nStreptococcus thermophilus dengan rerata diameter sebesar 15,56±0,58 mm.\r\nSimpulan: Eritromisin menghasilkan zona hambat terbesar terhadap pertumbuhan\r\nCutibacterium acnes secara in vitro dibandingkan dengan zona hambat yang\r\ndihasilkan oleh klindamisin dan probiotik Streptococcus thermophilus.\r\nKata kunci: Cutibacterium acnes, probiotik, Streptococcus thermophilus, zona\r\nhambat"^^<http://www.w3.org/2001/XMLSchema#string> .
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