<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <http://digilib.unila.ac.id/id/eprint/83192> .
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<http://digilib.unila.ac.id/id/eprint/83192> <http://purl.org/dc/terms/title> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://purl.org/ontology/bibo/abstract> "Pseudomonas aeruginosa dan Vibrio harveyi merupakan bakteri patogen di akua-\r\nkultur budi daya. Kedua bakteri ini sering mengakibatkan kerugian pada masyara-\r\nkat perikanan. Upaya yang sering dilakukan untuk mengatasinya yaitu dengan\r\n\r\npemberian antibiotik. Penggunaan antibiotik yang berlebihan dapat menimbulkan\r\n\r\nresistensi bakteri terhadap obat-obatan antibiotik komersil dan dapat membahaya-\r\nkan kesehatan manusia. Permasalahan resistensi bakteri mendorong penelitian un-\r\ntuk mencari agen antibakteri yang bersumber dari biota laut. Sargassum sp. memi-\r\nliki senyawa bioaktif yang memiliki berbagai macam pengaruh baik terhadap ke-\r\nsehatan salah satunya sebagai antibakteri. Tujuan penelitian untuk mengetahui\r\n\r\nprofil senyawa bioaktif dalam ekstrak Sargassum sp., dan uji aktivitas antibakteri\r\nterhadap bakteri patogen secara in vitro. Metode analisis profil senyawa bioaktif\r\n\r\nmenggunakan GC-MS dan uji aktivitas antibakteri dengan metode difusi agar. Ha-\r\nsil penelitian didapatkan adanya 33 senyawa bioaktif yang terkandung dalam eks-\r\ntrak Sargassum sp. dan berdasarkan literatur terdapat 14 senyawa yang teridentifi-\r\nkasi sebagai senyawa antibakteri di antaranya tetradecanoid acid; neophytadiene;\r\n\r\nphytol; 1,19 eicosadiene; hexadecanoid acid, metil ester; n-Hexadecanoid acid;\r\n5,8,11,14-eicosatetraenoic acid; arachidonic acid; 9-octadecenoic acid; squalene;\r\noctadecanoid acid; ergosta-5,24(28)-dien-3-ol; stigmasta-5,24(28)-dien-3-ol; dan\r\n\r\n(2R,3R,4aR,5S,8aS)-2-hydroxy-4a, dimethyl-3-(prop-1-en-2-yl) octahydronaph-\r\nthalen-1(2H)-one. Ekstrak Sargassum sp. mampu menghambat pertumbuhan bak-\r\nteri Pseudomonas aeruginosa dan Vibrio harveyi. Zona hambat terbentuk pada se-\r\nmua konsentrasi ekstrak yang diujikan dengan hasil terbesar berada pada konsen-\r\ntrasi 50 ppm yaitu 2,26 mm (Pseudomonas aeruginosa) dan 70 ppm yaitu 3,0 mm\r\n\r\n(Vibrio harveyi).\r\nKata kunci: Sargassum sp., Pseudomonas aeruginosa, Vibrio harveyi, GC-MS\r\n\r\n\r\nPseudomonas aeruginosa and Vibrio harveyi are pathogenic bacteria in aquacul-\r\nture. These two bacteria often cause losses to the fishing community. Efforts are\r\n\r\noften made to overcome them by giving antibiotics. Excessive use of antibiotics\r\ncan lead to bacterial resistance to commercial antibiotic drugs and can endanger\r\nhuman health. The problem of bacterial resistance encourages research to look for\r\n\r\nantibacterial agents sourced from marine biota. Sargassum sp. has bioactive com-\r\npounds that have a variety of good effects on health, one of which is as an anti-\r\nbacterial. The purpose of the study was to determine the profile of bioactive com-\r\npounds in Sargassum sp. extract, and test antibacterial activity against pathogenic\r\n\r\nbacteria in vitro. The method of analyzing the profile of bioactive compounds us-\r\ning GC-MS and antibacterial activity test with agar diffusion method. The results\r\n\r\nshowed that there were 33 bioactive compounds contained in the extract of Sar-\r\ngassum sp. and based on the literature there are 14 compounds identified as anti-\r\nbacterial compounds including tetradecanoid acid; neophytadiene; phytol; 1,19\r\n\r\neicosadiene; hexadecanoid acid, methyl ester; n-Hexadecanoid acid; 5,8,11,14-\r\n\r\neicosatetraenoic acid; arachidonic acid; 9-octadecenoic acid; squalene; octade-\r\ncanoid acid; ergos-ta-5,24(28)-dien-3-ol; stigmasta-5,24(28)-dien-3-ol; and\r\n\r\n(2R,3R,4aR,5S,8aS)-2-hydroxy-4a,dimethyl-3-(prop-1-en-2-yl)octahydronaphtha-\r\nlen-1(2H)-one. Sargassum sp. extract was able to inhibit the growth of Pseudomo-\r\nnas aeruginosa and Vibrio harveyi bacteria. Inhibition zones were formed at all\r\n\r\nconcentrations of the extract tested with the largest results being at a concentration\r\nof 50 ppm, namely 2.26 mm (Pseudomonas aeruginosa) and 70 ppm, namely 3.0\r\nmm (Vibrio harveyi).\r\nKeywords: Sargassum sp., Pseudomonas aeruginosa, Vibrio harveyi, GC-MS"^^<http://www.w3.org/2001/XMLSchema#string> .
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<http://digilib.unila.ac.id/id/document/2311102> <http://eprints.org/relation/ismediumThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2310938> .
<http://digilib.unila.ac.id/id/document/2311102> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/10/medium.jpg> .
<http://digilib.unila.ac.id/id/document/2311102> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/10/medium.jpg> .
<http://digilib.unila.ac.id/83192/10/medium.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "medium.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311103> .
<http://digilib.unila.ac.id/id/document/2311103> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311103> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311103> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310938> .
<http://digilib.unila.ac.id/id/document/2311103> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310938> .
<http://digilib.unila.ac.id/id/document/2311103> <http://eprints.org/relation/issmallThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2310938> .
<http://digilib.unila.ac.id/id/document/2311103> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/11/small.jpg> .
<http://digilib.unila.ac.id/id/document/2311103> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/11/small.jpg> .
<http://digilib.unila.ac.id/83192/11/small.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "small.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311104> .
<http://digilib.unila.ac.id/id/document/2311104> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311104> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311104> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311104> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311104> <http://eprints.org/relation/islightboxThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311104> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/12/lightbox.jpg> .
<http://digilib.unila.ac.id/id/document/2311104> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/12/lightbox.jpg> .
<http://digilib.unila.ac.id/83192/12/lightbox.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "lightbox.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311105> .
<http://digilib.unila.ac.id/id/document/2311105> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311105> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311105> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311105> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311105> <http://eprints.org/relation/ispreviewThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311105> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/13/preview.jpg> .
<http://digilib.unila.ac.id/id/document/2311105> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/13/preview.jpg> .
<http://digilib.unila.ac.id/83192/13/preview.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "preview.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311106> .
<http://digilib.unila.ac.id/id/document/2311106> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311106> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311106> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311106> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311106> <http://eprints.org/relation/ismediumThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311106> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/14/medium.jpg> .
<http://digilib.unila.ac.id/id/document/2311106> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/14/medium.jpg> .
<http://digilib.unila.ac.id/83192/14/medium.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "medium.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311107> .
<http://digilib.unila.ac.id/id/document/2311107> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311107> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311107> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311107> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311107> <http://eprints.org/relation/issmallThumbnailVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311107> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/15/small.jpg> .
<http://digilib.unila.ac.id/id/document/2311107> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/15/small.jpg> .
<http://digilib.unila.ac.id/83192/15/small.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "small.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311108> .
<http://digilib.unila.ac.id/id/document/2311108> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311108> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311108> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310935> .
<http://digilib.unila.ac.id/id/document/2311108> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310935> .
<http://digilib.unila.ac.id/id/document/2311108> <http://eprints.org/relation/isIndexCodesVersionOf> <http://digilib.unila.ac.id/id/document/2310935> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311109> .
<http://digilib.unila.ac.id/id/document/2311109> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311109> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311109> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311109> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311109> <http://eprints.org/relation/isIndexCodesVersionOf> <http://digilib.unila.ac.id/id/document/2310936> .
<http://digilib.unila.ac.id/id/document/2311109> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/17/indexcodes.txt> .
<http://digilib.unila.ac.id/id/document/2311109> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/17/indexcodes.txt> .
<http://digilib.unila.ac.id/83192/17/indexcodes.txt> <http://www.w3.org/2000/01/rdf-schema#label> "indexcodes.txt"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://eprints.org/ontology/hasDocument> <http://digilib.unila.ac.id/id/document/2311110> .
<http://digilib.unila.ac.id/id/document/2311110> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<http://digilib.unila.ac.id/id/document/2311110> <http://www.w3.org/2000/01/rdf-schema#label> "PROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum\r\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI\r\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi\r\n\r\n(JOHNSON & SHUK, 1936) (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/document/2311110> <http://eprints.org/relation/isVersionOf> <http://digilib.unila.ac.id/id/document/2310938> .
<http://digilib.unila.ac.id/id/document/2311110> <http://eprints.org/relation/isVolatileVersionOf> <http://digilib.unila.ac.id/id/document/2310938> .
<http://digilib.unila.ac.id/id/document/2311110> <http://eprints.org/relation/isIndexCodesVersionOf> <http://digilib.unila.ac.id/id/document/2310938> .
<http://digilib.unila.ac.id/id/document/2311110> <http://eprints.org/ontology/hasFile> <http://digilib.unila.ac.id/83192/18/indexcodes.txt> .
<http://digilib.unila.ac.id/id/document/2311110> <http://purl.org/dc/terms/hasPart> <http://digilib.unila.ac.id/83192/18/indexcodes.txt> .
<http://digilib.unila.ac.id/83192/18/indexcodes.txt> <http://www.w3.org/2000/01/rdf-schema#label> "indexcodes.txt"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://digilib.unila.ac.id/id/eprint/83192> <http://www.w3.org/2000/01/rdf-schema#seeAlso> <http://digilib.unila.ac.id/83192/> .
<http://digilib.unila.ac.id/83192/> <http://purl.org/dc/elements/1.1/title> "HTML Summary of #83192 \n\nPROFIL SENYAWA BIOAKTIF EKSTRAK RUMPUT LAUT Sargassum&#13;\nsp. DAN AKTIVITAS ANTIBAKTERI TERHADAP BAKTERI&#13;\nPseudomonas aeruginosa (CARLE GESSARD, 1882) DAN Vibrio harveyi&#13;\n&#13;\n(JOHNSON &amp; SHUK, 1936)\n\n" .
<http://digilib.unila.ac.id/83192/> <http://purl.org/dc/elements/1.1/format> "text/html" .
<http://digilib.unila.ac.id/83192/> <http://xmlns.com/foaf/0.1/primaryTopic> <http://digilib.unila.ac.id/id/eprint/83192> .
<http://digilib.unila.ac.id/id/subject/570> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/02/skos/core#Concept> .
<http://digilib.unila.ac.id/id/subject/570> <http://www.w3.org/2004/02/skos/core#prefLabel> "570 Biologi" .
<http://digilib.unila.ac.id/id/eprint/83192> <http://purl.org/dc/terms/subject> <http://digilib.unila.ac.id/id/subject/570> .
<http://digilib.unila.ac.id/id/subject/580> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/02/skos/core#Concept> .
<http://digilib.unila.ac.id/id/subject/580> <http://www.w3.org/2004/02/skos/core#prefLabel> "580 Tumbuh-tumbuhan, tanaman, botani, flora" .
<http://digilib.unila.ac.id/id/eprint/83192> <http://purl.org/dc/terms/subject> <http://digilib.unila.ac.id/id/subject/580> .
<http://digilib.unila.ac.id/id/subject/600> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/02/skos/core#Concept> .
<http://digilib.unila.ac.id/id/subject/600> <http://www.w3.org/2004/02/skos/core#prefLabel> "600 Teknologi (ilmu terapan)" .
<http://digilib.unila.ac.id/id/eprint/83192> <http://purl.org/dc/terms/subject> <http://digilib.unila.ac.id/id/subject/600> .
<http://digilib.unila.ac.id/id/subject/630> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/02/skos/core#Concept> .
<http://digilib.unila.ac.id/id/subject/630> <http://www.w3.org/2004/02/skos/core#prefLabel> "630 Pertanian dan teknologi yang berkaitan" .
<http://digilib.unila.ac.id/id/eprint/83192> <http://purl.org/dc/terms/subject> <http://digilib.unila.ac.id/id/subject/630> .