?url_ver=Z39.88-2004&rft_id=2017011067&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=PROFIL+SENYAWA+BIOAKTIF+ANTIBAKTERI+DARI+DAUN+SALAM%0D%0A(Syzygium+polyanthum)+MENGGUNAKAN+METODE+KLT+BIOAUTOGRAFI+DAN+LC-MS%2FMS&rft.creator=Pipit+Dwi+%2C+Haryani+&rft.subject=500+ilmu+pengetahuan+alam+dan+matematika&rft.subject=540+Kimia+dan+ilmu+yang+berhubungan&rft.subject=660+Teknik+kimia&rft.description=Meningkatnya+kasus+infeksi+bakteri+patogen+yang+resisten+terhadap+senyawa+antibiotik+menimbulkan+kebutuhan+mendesak+untuk+mencari+alternatif+senyawa+aktif+baru.+Penelitian+ini+bertujuan+untuk+mengevaluasi+profil+senyawa+bioaktif+dari+ekstrak+daun+salam+(S.+polyanthum)+yang+memiliki+aktivitas+sebagai+antibakteri+terhadap+bakteri+patogen+resisten.+Dalam+penelitian+ini+bakteri+resisten+diperoleh+dari+Dinas+Kesehatan+Bandar+Lampung+dan+sampel+daun+salam+diperoleh+dari+Desa+Candimas+2.+Daun+salam+diekstrak+menggunakan+air+mendidih+sampai+volume+menyusut+60%25.+Komponen+dalam+ekstrak+dianalisis+menggunakan+KLT%2C+dan+bioaktivitas+dianalisis+KLT+bioautografi.+Analisis+selanjutnya+untuk+mengetahui+komponen+aktif+yang+teramati+pada+bioautografi+menggunakan+LC-MS%2FMS.+Hasil+penelitian+diperoleh+ekstrak+daun+salam+fraksi+butanol+a2+memiliki+aktivitas+antibakteri+melalui+metode+KLT+bioautografi+terhadap+bakteri+S.aureus.+Hasil+karakterisasi+dengan+LC-MS%2FMS+diperoleh+profil+senyawa+bioaktif+dari+ekstrak+daun+salam+pada+sampel+a2+yaitu%2C+1-hydroxyanthraquinone%2C+3-+ethylamino-4-nitropyridine%2C1-Hexatriacontanamine%2C+N-Octyl-N-tetradecyl-1-hexadecanamine.%0D%0ABerdasarkan+profil+senyawa+yang+diperoleh+dan+potensi+aktivitas+antibakteri+terhadap+S.aureus+sehinga+dapat+dikaji+lebih+lanjut+sebagai+bahan+pengobatan+alternatif.%0D%0AKata+kunci%3A+senyawa+bioaktif%2C+tanaman+salam%2C+antibakteri.%0D%0A%0D%0AThe+increasing+cases+of+pathogenic+bacterial+infections+that+are+resistant+to+antibiotic+compounds+have+created+an+urgent+need+to+find+alternative+new+active+compounds.+This+study+aims+to+evaluate+the+profile+of+bioactive+compounds+from+bay+leaf+extract+(S.+polyanthum)+which+have+antibacterial+activity+against+resistant+pathogenic+bacteria.+In+this+study%2C+resistant+bacteria+were+obtained+from+the+Bandar+Lampung+Health+Office+and+bay+leaf+samples+were+obtained+from+Candimas+Village+2.+Bay+leaves+were+extracted+using+boiling+water+until+the+volume+shrank+by+60%25.+The+components+in+the+extract+were+analyzed+using+TLC%2C+and+bioactivity+was+analyzed+by+TLC+bioautography.+Further+analysis+to+determine+the+active+components+observed+in+bioautography+using+LC-MS%2FMS.+The+results+of+the+study+showed+that+bay+leaf+extract+with+butanol+a2+fraction+had+antibacterial+activity+through+the+TLC+bioautography+method+against+S.aureus+bacteria.+The+results+of+characterization+with+LC-MS%2FMS+obtained+a+profile+of+bioactive+compounds+from+bay+leaf+extract+in+sample+a2%2C+namely%2C+1-hydroxyanthraquinone%2C+3-ethylamino-4-nitropyridine%2C+1-Hexatriacontanamine%2C+N-Octyl-N-tetradecyl-1-hexadecanamine.+Based+on+the+profile+of+the+compounds+obtained+and+the+potential+antibacterial+activity+against+S.aureus%2C+it+can+be+studied+further+as+an+alternative+medicine.%0D%0AKeywords%3A+bioactive+compounds%2C+bay+leaf%2C+antibacterial.&rft.publisher=FAKULTAS+PERTANIAN&rft.date=2025-01-21&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F83983%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F83983%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F83983%2F3%2FSKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++Pipit+Dwi+%2C+Haryani+++(2025)+PROFIL+SENYAWA+BIOAKTIF+ANTIBAKTERI+DARI+DAUN+SALAM+(Syzygium+polyanthum)+MENGGUNAKAN+METODE+KLT+BIOAUTOGRAFI+DAN+LC-MS%2FMS.++FAKULTAS+PERTANIAN%2C+UNIVERSITAS+LAMPUNG.++++(Submitted)++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F83983%2F