?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=UJI+BIOAKTIVITAS+EKSTRAK+ETANOL+Gracilaria+sp.+SEBAGAI+REPELAN+NYAMUK+Aedes+aegypti+DALAM+SEDIAAN+SPRAY++&rft.creator=WANA+%2C+PUSPITA+&rft.subject=500+ilmu+pengetahuan+alam+dan+matematika&rft.subject=570+Biologi&rft.description=Demam+Berdarah+Dengue+mengalami+peningkatan+total+kasus+dan+angka+kematian+setiap++tahunnya.++Pencegahan++yang++umumnya++dilakukan++adalah++menggunakan+repelan+dengan+kandungan+DEET+(N%2CN-dietil-meta-toluamid)+yang+bersifat+korosif.+Diketahui++Gracilaria++sp.++mengandung++alkaloid%2C++flavonoid%2C++saponin%2C++triterpenoid%2C+steroid++dan++tanin++yang++bersifat++racun++bagi++nyamuk.++Tujuan++penelitian++ini++untuk+mengetahui++efektivitas++ekstrak++etanol++Gracilaria++sp.++sebagai++repelan++terhadap+nyamuk+Ae.+aegypti+dalam+sediaan+spray%2C+Effective+Concentration+50%25+(EC50)%2C+efek+iritasi%2C++dan++sifat++fisik++sediaan++spray++ekstrak++etanol++Gracilaria++sp..++Penelitian++ini+menggunakan+Rancangan+Acak+Lengkap+(RAL)+yang+terdiri+dari+5+konsentrasi+dan+5+kali+pengulangan.+Daya+proteksi+dianalisis+menggunakan+One+Way+ANOVA+dan+dilanjutkan+dengan+uji+Least+Significant+Difference+(LSD).+Efektivitas+konsentrasi+ekstrak++etanol++Gracilaria++sp.++sebagai++repelan++dianalisis++dengan++probit.++Hasil+penelitian++menunjukkan++spray++konsentrasi++5%25%2C++10%25%2C++15%25%2C++dan++20%25++memiliki+persentase++daya++proteksi++berturut++%E2%80%93++turut++sebesar++14%2C40%25%2C++31%2C81%25%2C++47%2C76%25%2C++dan+61%2C17%25.+Hasil+One+W+a+y+ANOVA+menunjukkan+nilai+p-value+%3D+0%2C00+dan+dilanjutkan+dengan++uji++LSD++yang++menunjukkan++adanya++perbedaan++daya++proteksi++siginifikan+antar+perlakuan%2C+yaitu+semakin+tinggi+konsentrasi+ekstrak+yang+diberikan%2C+semakin+sedikit+nyamuk+yang+hinggap+pada+lengan.+Hasil+analisis+probit+diperoleh+nilai+EC50+pada+konsentrasi+18%2C86%25.+Spray+konsentrasi+0%25+berwarna+putih++bening+dan+tidak+beraroma%2C++spray++konsentrasi++5%25%2C++10%25%2C++15%25%2C++dan++20%25++berwarna++cokelat++muda+hingga+cokelat+kehitaman+serta+aroma+amis+yang+khas+dari+rumput+laut+Gracilaria+sp..++Spray++bersifat++homogen++dan++tidak++memberikan++efek++iritasi++pada++kulit.+Kesimpulan%2C++spray++ekstrak++etanol++Gracilaria++sp.++menunjukkan++aktivitas++sebagai+repelan+nyamuk+Ae.+aegypti+terbaik+pada+konsentrasi+20%25.++%0D%0AKata+Kunci%3A+Ae.+aegypti%2C+Demam+Berdarah+Dengue%2C+Repelan%2C+Gracilaria+sp.%0D%0A%0D%0A%0D%0ADengue++fever++has++increased++in++total++cases++and++mortality++every++year.++Prevention++is+generally+done+by+using+repellant+with+DEET+(N%2CN-diethyl-meta-toluamide)+which+is+corrosive.+It+is+known+that+Gracilaria+sp.+contains+alkaloids%2C+flavonoids%2C+saponins%2C+triterpenoids%2C+steroids+and+tannins+that+are+toxic+to+mosquitoes.+The+purpose+of+this+study++was++to++determine++the++effectiveness++of++Gracilaria++sp.++ethanol++extract++as++a+repellent++against++Ae.++aegypti++mosquitoes++in++spray++preparations%2C++Effective+Concentration+50%25+(EC50)%2C+irritating+effects%2C+and+physical+properties+of+Gracilaria+sp.++ethanol++extract++spray++preparations.++This++study++used++a++completely++randomized+design++(CRD)++consisting++of++5++concentrations++and++5++repetitions.++The++protection+power++was++analyzed++using++One++Way++ANOVA++and++continued++with++the++Least+Significant++Difference++(LSD)++test.++The++effectiveness++of++Gracilaria++sp.++ethanol+extract+concentration+as+repellant+was+analyzed+by+probit.+The+results+showed+that+spray++concentrations++of++5%25%2C++10%25%2C++15%25%2C++and++20%25++had++a++percentage++of++protection+power+of+14.40%25%2C+31.81%25%2C+47.76%25%2C+and+61.17%25%2C+respectively.+The+results+of+One+Way+ANOVA++showed++a++p-value++%3D++0.00++and++continued++with++the++LSD++test++which+showed+a+significant+difference+in+protection+power+between+treatments%2C+namely+the+higher+the+concentration+of+extract+given%2C+the+fewer+mosquitoes+that+landed+on+the+arm.++The++results++of++probit++analysis++obtained++an++EC50++value++at++a++concentration++of+18%2C86%25.+Spray+concentration+0%25+is+clear+white+and+unscented%2C+spray+concentration+5%25%2C+10%25%2C+15%25%2C+and+20%25+is++light+brown+to+blackish+brown+and+has+a+fishy+aroma+typical+of+Gracilaria+sp.+seaweed.+The+spray+was+homogeneous+and+had+no+irritating+effect++on++the++skin.++In++conclusion%2C++Gracilaria++sp.++ethanol++extract++spray++showed+activity+as+the+best+repellent+for+Ae.+aegypti+mosquitoes+at+20%25+concentration.%0D%0AKeywords%3A+Ae.+aegypti%2C+Dengue+Hemorrhagic+Fever%2C+Repllent%2C+Gracilaria+sp.++&rft.publisher=FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM+&rft.date=2025-02-11&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F84365%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F84365%2F3%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F84365%2F2%2FSKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++WANA+%2C+PUSPITA+++(2025)+UJI+BIOAKTIVITAS+EKSTRAK+ETANOL+Gracilaria+sp.+SEBAGAI+REPELAN+NYAMUK+Aedes+aegypti+DALAM+SEDIAAN+SPRAY.++FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM+%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F84365%2F