?url_ver=Z39.88-2004&rft_id=1957011020&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=SINTESIS+DAN+KARAKTERISASI+NANOPARTIKEL+DARI+PENGGABUNGAN+NANOKITOSAN-PLA+DENGAN+VARIASI+NANOSELULOSA&rft.creator=Aidha+%2C+Natasya+Pramudhita&rft.subject=500+ilmu+pengetahuan+alam+dan+matematika&rft.description=Telah+dilakukan+penelitian+yang+bertujuan+untuk+mensintesis+dan+mengkarakterisasi+dari+penggabungan+nanopartikel+kitosan-PLA+dengan+variasi+nanoselulosa.+Nanopartikel+kitosan-PLA+yang+dimodifikasi+dengan+nanoselulosa+telah+disintesis+melalui+metode+hidrolisis+asam+untuk+nanoselulosa%2C+gelasi+ionik+untuk+nanopartikel+kitosan-PLA%2C+dan+metode+penggabungan+sederhana.+Metode+hidrolisis+asam+dengan+variasi+penambahan+asam+sulfat+(10%2C+20%2C+dan+30+mL%2Fgr)+terhadap+selulosa+menghasilkan+nanoselulosa+dengan+ukuran+partikel+229%2C8+nm%2C+488%2C7+nm%2C+dan+361%2C3+nm.+Karakterisasi+menggunakan+XRD+menunjukkan+bahwa+penambahan+asam+berpengaruh+terhadap+rendemen+dan+karakteristik+nanoselulosa.+Sintesis+nanopartikel+kitosan-PLA+melalui+metode+gelasi+ionik+dengan+penambahan+Na-TPP+menghasilkan+nanopartikel+kitosan-PLA+dengan+ukuran+partikel+sebesar+310%2C7+nm.+Nanopartikel+kitosan-PLA+yang+dihasilkan+kemudian+digabungkan+dengan+nanoselulosa+dengan+variasi+10+mL%2Fgr+dan+dikarakterisasi+menggunakan+FTIR.+Hasil+analisis+FTIR+menunjukkan+adanya+interaksi+antar+gugus+fungsi+dari+nanopartikel+kitosan-PLA+dan+nanoselulosa.+Penelitian+ini+menunjukkan+bahwa+nanopartikel+kitosan-PLA+yang+dimodifikasi+dengan+nanoselulosa+berpotensi+untuk+diterapkan+dalam+bidang+biomedis+dan+farmasi%2C+khususnya+untuk+penghantaran+obat+dan+rekayasa+jaringan.%0D%0A%0D%0AKata+Kunci+%3A+Nanopartikel%2C+Nanoselulosa%2C+Kitosan-PLA%2C+FTIR+dan+PSA%0D%0A%0D%0A%0D%0A%0D%0A%0D%0A%0D%0A%0D%0Aabstract%0D%0A%0D%0AA+study+was+conducted+to+synthesize+and+characterize+the+incorporation+of+chitosan-PLA+nanoparticles+with+variations+of+nanocellulose.+Chitosan-PLA+nanoparticles+modified+with+nanocellulose+have+been+synthesized+through+acid+hydrolysis+method+for+nanocellulose%2C+ionic+gelation+for+chitosan-PLA+nanoparticles%2C+and+simple+incorporation+method.+Acid+hydrolysis+method+with+variation+of+sulfuric+acid+addition+(10%2C+20%2C+and+30+mL%2Fgr)+to+cellulose+produced+nanocellulose+with+particle+size+of+229%2C8+nm%2C+488%2C7+nm%2C+and+361%2C3+nm.+Characterization+using+XRD+showed+that+the+addition+of+acid+affected+the+yield+and+characteristics+of+nanocellulose.+Synthesis+of+chitosan-PLA+nanoparticles+through+ionic+gelation+method+with+the+addition+of+Na-TPP+produced+chitosan-PLA+nanoparticles+with+a+particle+size+of+310%2C7+nm.+The+resulting+chitosan-PLA+nanoparticles+were+then+combined+with+nanocellulose+with+a+variation+of+10+mL%2Fgr+and+characterized+using+FTIR.+The+results+of+FTIR+analysis+showed+the+interaction+between+functional+groups+of+chitosan-PLA+nanoparticles+and+nanocellulose.+This+study+shows+that+chitosan-PLA+nanoparticles+modified+with+nanocellulose+have+the+potential+to+be+applied+in+biomedical+and+pharmaceutical+fields%2C+especially+for+drug+delivery+and+tissue+engineering.%0D%0A%0D%0AKeywords%3A+Nanoparticles%2C+Nanocellulose%2C+Chitosan-PLA%2C+FTIR+and+PSA&rft.publisher=FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM+&rft.date=2025-02-03&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F86543%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F86543%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F86543%2F3%2FSKRIPSI%2520TANPA%2520BAB%2520PEMBAHASAN.pdf&rft.identifier=++Aidha+%2C+Natasya+Pramudhita++(2025)+SINTESIS+DAN+KARAKTERISASI+NANOPARTIKEL+DARI+PENGGABUNGAN+NANOKITOSAN-PLA+DENGAN+VARIASI+NANOSELULOSA.++FAKULTAS+MATEMATIKA+DAN+ILMU+PENGETAHUAN+ALAM+%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F86543%2F