?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=ANALISIS+FAKTOR+RISIKO+TERHADAP+EFEKTIVITAS+PROFILAKSIS%0D%0ASTRESS+ULCER+GOLONGAN+PROTON+PUMP+INHIBITOR+DI+%0D%0AINTENSIVE+CARE+UNIT+(ICU)+RSUD+DR.H+ABDUL+MOELOEK%0D%0APROVINSI+LAMPUNG+&rft.creator=GHINA%2C+NAZHIFAH+AZ+ZAHRA&rft.subject=600+Teknologi+(ilmu+terapan)&rft.subject=602+Aneka+ragam+tentang+teknologi+dan+ilmu+terapan&rft.subject=610+Ilmu+kedokteran%2C+ilmu+pengobatan+dan+ilmu+kesehatan&rft.description=+%0D%0ALatar+Belakang%3A+Risiko+terjadinya+perdarahan+pada+saluran+cerna+dapat+meningkat%0D%0Asaat+pasien+mendapatkan+pelayanan+di+Intensive+Care+Unit+(ICU)%2C+sehingga%0D%0Apenggunaan+agen+profilaksis+stress+ulcer+yang+tepat+dapat+meminimalisir+kejadian%0D%0Aperdarahan+saluran+cerna.+Penelitian+ini+bertujuan+untuk+mengetahui+hubungan%0D%0Aantara+faktor+risiko+terhadap+efektivitas+penggunaan+profilaksis+stress+ulcer%2C%0D%0Agolongan+Proton+Pump+Inhibitor+(PPI)+pada+pasien+ICU+RSUD+DR.H.Abdul%0D%0AMoeloek+Provinsi+Lampung+periode+Januari+%E2%80%93+Maret+2025.%0D%0AMetode+Penelitian%3A+Penelitian+ini+menggunakan+metode+analisis+observasional%0D%0Adengan+pendekatan+cross-sectional.+Subyek+penelitian+adalah+semua+pasien+ICU+di%0D%0ARSUD+Abdul+Moeloek+Provinsi+Lampung+periode+Januari+%E2%80%93+Maret+2025+yang%0D%0Amemenuhi+kriteria+inklusi+dan+eksklusi.+%0D%0AHasil+Penelitian%3A+Subjek+penelitian+ini+berjumlah+70+pasien+dengan+pembagian%0D%0Akelompok+terapi+omeprazol+63+(90%25)+pasien+dan+lansoprazol+7+(10%25)+pasien.%0D%0ATerdapat+3+(4%2C2%25)+pasien++kelompok+omeprazol+yang+memiliki+faktor+risiko+%3E1%0D%0Amengalami+perdarahan+dan+satu+(1%2C4%25)+pasien+yang+tidak+memiliki+faktor+risiko%0D%0Amengalami+perdarahan+saluran+cerna.%0D%0ASimpulan+Penelitian%3A+Hasil+penelitian+menunjukkan+bahwa+tidak+terdapat%0D%0Ahubungan+antara+status+faktor+risiko+(p-value%3D+0%2C262)+terhadap+terjadinya%0D%0Aperdarahan+saluran+cerna+dan+terdapat+pengaruh+jumlah+faktor+risiko+pasien+(pvalue%3D%0D%0A%0D%0A0%2C048)+terhadap+terjadinya+perdarahan+saluran+cerna+pada+pasien+yang%0D%0Amendapatkan+PPI+sebagai+profilaksis+stress+ulcer.%0D%0AKata+Kunci%3A+Profilaksis+Stress+Ulcer%2C+Proton+Pump+Inhibitor%2C+Stress+Ulcer%2C%0D%0APerdarahan+Saluran+Cerna%2C+Intensive+Care+Unit+%0D%0A%0D%0A%0D%0A+%0D%0ABackground%3A+The+risk+of+gastrointestinal+bleeding+can+increase+in+patients%0D%0Areceiving+care+in+the+Intensive+Care+Unit+(ICU)%2C+thus+the+appropriate+use+of+stress%0D%0Aulcer+prophylactic+agents+can+minimize+the+incidence+of+gastrointestinal+bleeding.%0D%0AThis+study+aims+to+determine+the+relationship+between+risk+factors+and+the%0D%0Aeffectiveness+of+stress+ulcer+prophylaxis+using+the+Proton+Pump+Inhibitor+(PPI)+class%0D%0Ain+ICU+patients+at+RSUD+DR.+H.+Abdul+Moeloek%2C+Lampung+Province%2C+during+the%0D%0Aperiod+of+January+%E2%80%93+March+2025.%0D%0AMethods%3A+This+research+employed+an+analytical+observational+method+with+a+crosssectional%0D%0A%0D%0Aapproach.+The+study+subjects+were+all+ICU+patients+at+RSUD+Abdul%0D%0AMoeloek%2C+Lampung+Province%2C+from+January+to+March+2025+who+met+the+inclusion%0D%0Aand+exclusion+criteria.%0D%0AResults%3A+The+study+included+70+patients%2C+with+63+(90%25)+receiving+omeprazole%0D%0Atherapy+and+7+(10%25)+receiving+lansoprazole.+Among+the+omeprazole+group%2C+3%0D%0Apatients+(4.2%25)+with+more+than+one+risk+factor+experienced+gastrointestinal+bleeding%2C%0D%0Aand+1+patient+(1.4%25)+without+risk+factors+also+experienced+gastrointestinal+bleeding.%0D%0AConclusion%3A+The+results+showed+that+there+was+no+significant+relationship+between%0D%0Arisk+factor+status+(p-value%3D+0.262)+and+the+incidence+of+gastrointestinal+bleeding.%0D%0AHowever%2C+there+was+a+significant+influence+of+the+number+of+risk+factors+(p-value%3D%0D%0A0.048)+on+the+incidence+of+gastrointestinal+bleeding+in+patients+receiving+PPI+as%0D%0Astress+ulcer+prophylaxis.%0D%0A%0D%0AKeywords%3A+Stress+Ulcer+Prophylaxis%2C+Proton+Pump+Inhibitor%2C+Stress+Ulcer%2C%0D%0AGastrointestinal+Bleeding%2C+Intensive+Care+Unit+&rft.publisher=FAKULTAS+KEDOKTERAN&rft.date=2025-05-20&rft.type=Skripsi&rft.type=NonPeerReviewed&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F87814%2F1%2FABSTRAK.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F87814%2F2%2FSKRIPSI%2520FULL.pdf&rft.format=text&rft.identifier=http%3A%2F%2Fdigilib.unila.ac.id%2F87814%2F3%2FSKRIPSI%2520FULL%2520TANPA%2520PEMBAHASAN.pdf&rft.identifier=++GHINA%2C+NAZHIFAH+AZ+ZAHRA++(2025)+ANALISIS+FAKTOR+RISIKO+TERHADAP+EFEKTIVITAS+PROFILAKSIS+STRESS+ULCER+GOLONGAN+PROTON+PUMP+INHIBITOR+DI+INTENSIVE+CARE+UNIT+(ICU)+RSUD+DR.H+ABDUL+MOELOEK+PROVINSI+LAMPUNG.++FAKULTAS+KEDOKTERAN%2C+UNIVERSITAS+LAMPUNG.+++++&rft.relation=http%3A%2F%2Fdigilib.unila.ac.id%2F87814%2F