Digital Library: No conditions. Results ordered -Date Deposited. 2024-03-29T06:13:03ZEPrintshttp://digilib.unila.ac.id/images/sitelogo.pnghttp://digilib.unila.ac.id/2016-08-08T03:25:36Z2016-08-08T03:25:36Zhttp://digilib.unila.ac.id/id/eprint/23337This item is in the repository with the URL: http://digilib.unila.ac.id/id/eprint/233372016-08-08T03:25:36ZKAJIAN AKTIVITAS ANTIBAKTERI SENYAWA TRIFENILTIMAH(IV)
4-HIDROKSIBENZOAT DAN TRIFENILTIMAH(IV) 4-
KLOROBENZOAT TEHADAP BAKTERI GRAM POSITIF Bacillus sp.Dalam penelitian ini telah dilakukan sintesis senyawa trifeniltimah(IV) 4-
hidroksibenzoat dan trifeniltimah(IV) 4-klorobenzat dari senyawa
trifeniltimah(IV) hidroksida dengan ligan asam 4-hidroksibenzoat dan asam 4-
klorobenzoat, kemudian didapatkan serbuk putih dengan berat masing-masing
1,3105 gram (89,57%) dan 1,333 gram (87,90%). Hasil karakterisasi dengan
spektrofotometer IR tedapat serapan C=O dari kedua senyawa hasil sintesis pada
daerah 1617,18 cm-1 dan daerah 1640,11 cm-1 yang menunjukkan telah
terbentuknya senyawa hasil sintesis. Hasil karakterisasi dengan spektrofotometer
UV-Vis didapatkan transisi elektron π→π* dan n→π* berturut-turut yaitu pada
λmaks 232,00 nm dan 305,00 nm, serta 237,00 nm dan 282,00 nm. Karakterisasi
dengan mikroelemental analyzer menunjukkan bahwa senyawa hasil telah murni.
Pengujian aktivitas antibakteri pada metode difusi didapatkan senyawa
trifeniltimah(IV) 4-klorobenzoat memiliki aktivitas antibakteri terbaik dengan
konsentrasi 300 ppm dan pada uji dilusi menunjukkan senyawa trifeniltimah(IV)
4-klorobenzoat memiliki aktivitas antibakteri terbaik dengan kadar 0,75 mg dalam
15 mL media agar.
Kata kunci : antibakteri, Bacillus sp., trifeniltimah(IV) 4-hidroksibenzoat,
trifeniltimah(IV) 4-klorobenzoat.
ABSTRACT
In this research the syntheses of triphenyltin(IV) 4-hydroxybenzoate and
triphenyltin(IV) 4-chlorobenzoate compounds have been conducted by reacting
triphenyltin(IV) hydroxide with ligands of 4-hydroxybenzoic acid and 4-
chlorobenzoic acid, the products obtaineds were white powder with the weight of
1.3105 gram (89.57%) and 1.333 gram (87.90%), respectively. The
characterization with IR spectrometry showed functional group of C=O of the
synthesized compounds in the area of 1617.18 cm-1 and 1640.11 cm-1 showing the
formation of compounds synthesized. The characterization with UV-Vis
spectrometry showed electron transition of π→π* and n→π* with λmax 232.00 nm
and 305.00 nm for triphenyltin(IV) 4-hydroxybenzoate, and 237.00 nm and
282.00 nm for triphenyltin(IV) 4-chlorobenzoate. The results of microelemental
analyzer showed that the compounds synthesized have high purity with the
difference with the theory was less than 2%. The result of antibacterial activity
test with diffusion method for triphenyltin(IV) 4-chlorobenzoic have the best
antibacterial activity at concentration of 300 ppm, while the dilution test showed
that the triphenyltin(IV) 4-chlorobenzoic have the best of antibacterial activity at
0.75 mg in 15 mL media.
Keywords: antibacterial, Bacillus sp., triphenyltin(IV) 4-hydroxybenzoate, and
triphenyltin(IV) 4-chlorobenzoate. 1217011001 ADI SETIAWANadi70598@gmail.com