PENGARUH PERBEDAAN DURASI PAPARAN ASAP PEMBAKARAN BAHAN ORGANIK TERHADAP GAMBARAN HISTOPATOLOGI PARENKIM PARU TIKUS PUTIH (Rattus novergicus) JANTAN GALUR Sprague dawley

Tiara Anggraini, 1118011134 (2014) PENGARUH PERBEDAAN DURASI PAPARAN ASAP PEMBAKARAN BAHAN ORGANIK TERHADAP GAMBARAN HISTOPATOLOGI PARENKIM PARU TIKUS PUTIH (Rattus novergicus) JANTAN GALUR Sprague dawley. Fakultas Kedokteran, Universitas Lampung.

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2.ABSTRACT.pdf

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3.ABSTRAK.pdf

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4. COVER DALAM.pdf

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5.PERSETUJUAN.pdf

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6.MENGESAHKAN.pdf

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7.PERNYATAAN.pdf

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8.RIWAYAT HIDUP.pdf

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9.HALAMAN PERSEMBAHAN.pdf

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10.SANWACANA.pdf

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11.DAFTAR ISI.pdf

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12.DAFTAR TABEL.pdf

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13.DAFTAR GAMBAR.pdf

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14.DAFTAR LAMPIRAN.pdf

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15.BAB I.pdf

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BAB II.pdf

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17.BAB III.pdf

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18.BAB IV.pdf
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19.BAB V.pdf

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20. DAFTAR PUSTAKA.pdf

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Abstrak (Berisi Bastraknya saja, Judul dan Nama Tidak Boleh di Masukan)

abstrak bahasa indonesia : Bahan organik terdapat banyak di alam khususnya hutan. Kebakaran hutan di Indonesia bukan suatu fenomena baru karena frekuensi dan prevalensi terjadinya semakin meningkat setiap tahun. Asap yang dihasilkan dari kebakaran hutan mengandung beberapa zat yang bersifat radikal bebas seperti karbon monoksida, materi partikulat, nitrogen dioksida, sulfur dioksida dan volatile organic compounds yang apabila terpapar dapat berpengaruh pada beberapa organ tubuh seperti jantung, darah, saraf, mata dan paru. Pada organ paru dapat menyebabkan kerusakan pada parenkim paru. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh perbedaan durasi paparan asap pembakaran bahan organik terhadap gambaran hisopatologi parenkim paru tikus putih (Rattus novergicus) jantan galur Sprague dawley. Pada penelitian ini, 25 ekor tikus putih berumur 8–10 minggu dibagi menjadi 5 kelompok secara acak dan diberi perlakuan selama 7 hari. K(–) tidak diberi paparan, P1 dipapar asap selama 1 jam/hari, P2 diapapar asap selama 2 jam/hari, P3 dipapar asap selama 3 jam/hari dan P4 dipapar asap selama 4 jam/hari. Hasil penelitian menunjukkan bahwa rerata skoring kerusakan parenkim paru pada K(–): 0, P1: 2,6, P2: 4,6, P3: 6,6 dan P4: 8,0. Data yang diperoleh diuji dengan Uji Kruskal Wallis didapatkan perbedaan bermakna dengan nilai p=0,000 (p<0,05). Terdapat pengaruh perbedaan durasi paparan asap pembakaran bahan organik terhadap gambaran histopatologi parenkim paru tikus putih (Rattus novergicus) jantan galur Sprague dawley. abstrak bahasa inggris : There are much organic material in the nature especially in the forest. In Indonesia, forest fire is not a new phenomenon because the frequency and prevalency are increasing every year. Smoke of the forest fires contain some of the free radical substances such as carbon monoxide, particulate matter, nitrogen dioxide, sulfur dioxide and volatile organic compounds that influence to many organs such as heart, blood, nerve, eyes and lung. In lung, it damages lung parenchym. The purpose of this study is to determine effect of different duration from organic material by smoke exposure duration to lung parenchymal histopathology in male rats Sprague dawley strain. In this study, 25 male rats about 8–10 weeks are divided randomly into 5 groups and treated for 7 days. K(–) is not given any exposure, P1, P2, P3 and P4 are exposure by smoke in 1 hour/day, 2 hours/day, 3 hours/day, 4 hours/day. The result showed that the average score of parenchymal lung damage are K(–): 0, P1: 2.6, P2: 4.6, P3: 6.6, P4: 8.0. With Kruskal Wallis test, there is a significant difference with p=0.00 (p<0.05). There is an effect of different duration from organic material by smoke burning exposure to lung parenchymal histopathology in male rats Sprague dawley strain.

Jenis Karya Akhir: Skripsi
Subyek:
> Karya Karya Umum = 000
Program Studi: Fakultas Kedokteran > Prodi Pendidikan Dokter
Pengguna Deposit: 8529803 . Digilib
Date Deposited: 27 Jan 2015 03:23
Terakhir diubah: 27 Jan 2015 03:23
URI: http://digilib.unila.ac.id/id/eprint/6482

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