PERBANDINGAN NILAI MEAN PLATELET VOLUME (MPV) PADA PASIEN STROKE NON HEMORAGIK DAN STROKE HEMORAGIK

Vandy Ikra, 1118011131 (2015) PERBANDINGAN NILAI MEAN PLATELET VOLUME (MPV) PADA PASIEN STROKE NON HEMORAGIK DAN STROKE HEMORAGIK. Fakultas Kedokteran, Universitas Lampung.

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Abstrak (Berisi Bastraknya saja, Judul dan Nama Tidak Boleh di Masukan)

Abstrak Stroke adalah penyakit multifaktoral dengan berbagai penyebab disertai manifestasi mayor, dan penyebab kecacatan dan kematian di negara-negara maju maupun negara berkembang. Di Indonesia diperkirakan 500.000 penduduk terkena serangan stroke dan sekitar 25% orang meninggal dan sisanya mengalami cacat ringan sampai berat. Mean platelet volume (MPV) adalah sebuah indikator dari fungsi platelet atau aktivitasnya. Platelet memainkan peran penting pada patofisiologi stroke non hemoragik tetapi pada patogenesis stroke hemoragik belum begitu dimengerti. Penelitian ini bertujuan untuk mengetahui perbandingan nilai MPV pada pasien stroke non hemoragik dan stroke hemoragik. Penelitian ini merupakan penelitian deskriptif analitik komparatif dengan pendekatan Retrospective yang dilakukan di Bagian Saraf Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Bandar Lampung, dengan cara meninjau kembali rekam medis pesien yang menjalani rawat inap di Ruang Bougenvil pada tahun 2014. Teknik pengambilan sampel yang digunakan adalah teknik purposive sampling. Berdasarkan kriteria inklusi didapatkan 44 pasien yang didiagnosa stroke non hemoragik dan 44 pasien yang didiagnosis stroke hemoragik, Data dianalisis menggunakan uji T independent. Hasil dari penelitian ini didapatkan rerata nilai MPV pada pasien stroke non hemoragik sebesar 9,905 fl dan stroke hemoragik sebesar 9,548 fl. Perbandingan nilai MPV pada pasien stroke non hemoragik dan stroke hemoragik bermakna secara statistik dengan p= 0,000. Dari penelitian ini dapat disimpulkan bahwa terdapat perbedaan nilai MPV pada pasien stroke non hemoragik dan stroke hemoragik. Kata kunci: MPV, stroke non hemoragik, stroke hemoragik Abstract dalam bahasa inggris Stroke are multifactoral disease with various cause, accompanied with major manifestation, and became cause of disablement and death in developed country and also developing country. 500.000 of Indonesian had stroke, and about 25% died, the rest are had mild to severe disablement. Mean platelet volume (MPV) is an indicator of platelet reactivity. Platelets play an important role in the pathophysiology of ischemic stroke but the effect in the pathogenesis of hemorrhagic stroke is poorly understood. The objective is to examine the comparison level of mean platelet volume in non hemorrhagic stroke and hemorrhagic stroke patients. This research is a comparative analytic descriptive research with retrospective approach that been held in Neurologic Department of RSUD H. Abdul Moeloek Bandar Lampung, by looking to patient with hospital treatment’s medical records in Bougenvil room on 2014. Purposive sampling were being used as sampling methods. Based on inclusion criteria, there is 44 patients with non-hemorrhagic stroke, and 44 patients with hemorrhagic stroke. The data been analyze by using T independent test. The result is MPV level in non-hemorrhagic stroke is 9,905fl and in hemorrhagic stroke is 9,548 fl. The comparison MPV level in non-hemorrhagic stroke and hemorrhagic stroke is significant by statistic with p= 0,000. The conclusion are there is a differentiation of MPV level between non-hemorrhagic stroke and hemorrhagic stroke. Keywords: hemorrhagic stroke, MPV, non-hemorrrhagic

Jenis Karya Akhir: Skripsi
Subyek:
Program Studi: Fakultas Kedokteran > Prodi Pendidikan Dokter
Pengguna Deposit: 3951056 .Vandy Ikra
Date Deposited: 28 Jan 2015 04:42
Terakhir diubah: 28 Jan 2015 04:42
URI: http://digilib.unila.ac.id/id/eprint/6513

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